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Promotion of functional heterotrimeric type I collagen via transfection in osteogenesis imperfecta fibroblasts
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Osteogenesis imperfecta (OI) is a heritable disorder due to mutations in type I collagen. Normal type I collagen forms a heterotrimeric protein comprised of two pro1(I) chains and one pro2(I) chain [1(I)22(I)]. The ...
The role of Periostin in regulating the biomechanical properties of cushion tissue
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
During embryonic heart development the atrio-ventricular (AV) cushions swell and fuse to form the valves and septa of the adult heart. Initially, the cushions appear as swellings on the interior wall of the AV canal and ...
Molecular free volume and viscosity changes in non-Newtonian fluids probed with molecular rotors
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
An empirical relationship between molecular free volume and viscosity has been established (Doolittle AK, J Appl. Phys. 1952; 23: 236-9). Non-Newtonian fluids hold much importance to scientific study because of their ...
Detection of Sad genes in various species of Neurospora
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Neurospora crassa is a haploid fungus that reproduces asexually during vegetative growth. However, in a nitrogen deficient environment, the two mating-type cells, A and a, can fuse together and enter the sexual cycle. ...
Reduction of rhenium (V) oxo Schiff Base Complexes with triphenyl phosphine ligands
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
One approach to the treatment of cancer is to direct beta-emitting radionuclide to the cancer site where the radiation destroys the cancer cells. This can be achieved by coordinating the radioisotope in a very stable ...
"Either he was too weak, or the world was too strong" : motifs of male wounds and healing in African American literature
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
African American men throughout history have tried to establish and define their identities, collectively and individually, beyond those formed, forced, and fashioned by western civilization. Consequently, they have inflicted ...
Issues with scale using very high resolution digital aerial photographs
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
This study involves the use of remote sensing equipment to observe plant communities. A remote sensor is any instrument that gathers information about an object or area from a distance. Advanced cameras, the most common ...
Effects of forest management practices on treefrog oviposition site choice
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Globally, amphibian populations are declining faster than those of birds or mammals. Habitat destruction is considered the primary cause of these declines; however, what remains partly unexplored is the idea that some ...
Synthesis and binding studies of novel sigma receptor ligands
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Sigma receptors are binding sites that are found in the brain, in the endocrine and immune systems, and also in the lungs, kidneys, intestines, muscles and especially the liver. They are classified into two subtypes, sigma1 ...
Stroke risk factors and awareness study
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Cerebrovascular Accidents, also known as strokes, are the third leading cause of death in the United States. It is estimated that more than 275,000 people die from strokes every year (American Heart Association 2003). In ...
How the revolutionary thought of two West Indian intellectuals predicts and explains post-independence African problems
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Though most of Africa gained independence from European colonial rule by 1960, today the continent is still plagued by poverty, ignorance, corruption, internal conflict, and external control. These results are now clear ...
The synthesis of peptide-PNA conjugates
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
In two long term studies of non-Hodgkin's Lymphoma (NHL), the only clinical feature associated with a high relapse rate and treatment resistance is the presence of the B-cell lymphoma/leukemia-2(bcl-2) proto-oncogene in ...
Identifying Lepidopteran resistance within hcf mutants
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Southwestern corn borer (SWCB) and fall armyworm (FAW) feeding on maize causes extensive crop damage in the United States. Previous proteomic analysis comparing resistant and susceptible lines of maize indicates genes found ...
Quantitative trait loci for seminal root angle and number in the maize IBM population
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
In maize, seminal roots develop and the primary root system deteriorates as the plant matures. The seminal roots comprise the majority of the root system of the adult plant and give the plant stability against lodging. ...
Characterization of N gene homologs in Nicotiana species
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
We have developed a new variety of Nicotiana, N. edwardsonii var. Columbia, that can be used as a bridge plant to move virus resistance genes from N. glutinosa to N. clevelandii, and have made crosses between N. edwardsonii. ...
Mean value formulas for differential operators
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
The main goal of our research is to discuss Mean Value Formulas for solutions of partial differential equations of a certain form (see 1 below) where A is a symmetric, positive definite, real-valued matrix. Such equations ...
Retension of knobs in chromosome tips in maize
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Knobs are deeply staining chromosomal sites on maize chromosomes. Molecularly, they are composed of a 180 base pair repeat. Their positions on the chromosomes are variable but usually internal in maize. In relatives, the ...
The effects of even-aged cutting on density and pairing success of Worm-eating Warblers
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
It is important for researchers to be aware of how timber management practices affect songbird populations. Certain forest management techniques can cause declines in breeding habitat of Neotropical migrant songbirds that ...
Point mutation of an RGD sequence in the human P2Y2 receptor to a QGD sequence conserves Go-mediated signal transduction
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
The P2Y2 nucleotide receptor is a Go/q coupled receptor that is activated equipotently by extracellular nucleotides such as ATP or UTP and is upregulated in a variety of tissues in response to injury or stress. The biological ...
Synthesis and characterization of amorphous astrominerals
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Asymptotic Giant Branch (AGB) stars are the main contributors of solid material (dust) to the interstellar medium. The dust forms as gas escaping from the star cools and condenses to form a circumstellar dust shell. Around ...