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Investigation of 89 candidate gene variants for effects on all-cause mortality following acute coronary syndrome
(2008-07-12)
Abstract
Background
Many candidate genes have been reported to be risk factors for acute coronary syndrome (ACS), but their impact on clinical prognosis following ACS is unknown.
...
Implementing an innovative consent form: the PREDICT experience
(2008-12-31)
Abstract
Background
In the setting of coronary angiography, generic consent forms permit highly variable communication between ...
Electronic health records in outpatient clinics: perspectives of third-year medical students
(2008-03-31)
Abstract
Background
United States academic medical centers are increasingly incorporating electronic health records (EHR) into ...
HAPSIMU: a genetic simulation platform for population-based association studies
(2008-08-05)
Abstract
Background
Population structure is an important cause leading to inconsistent results in population-based association ...
Motivational Interviewing for encouraging quit attempts among unmotivated smokers: Study protocol of a randomized, controlled, efficacy trial.
(2012-06-19)
Abstract
Background
Although the current Clinical Practice Guideline recommend Motivational Interviewing for use with smokers not ready to quit, the strength of evidence for its use is rated ...
delta-Tocotrienol and quercetin reduce serum levels of nitric oxide and lipid parameters in female chickens
(2011-02-28)
Abstract
Background
Chronic, low-grade inflammation provides a link between normal ageing and the pathogenesis of age-related diseases. A series of in vitro tests confirmed the strong anti-inflammatory activities ...
Tocotrienols inhibit lipopolysaccharide-induced pro-inflammatory cytokines in macrophages of female mice.
(2010-12-16)
Abstract
Background
Inflammation has been implicated in cardiovascular disease, and the important role of proteasomes in the development of inflammation and other macrophage functions has been demonstrated. ...
Autonomous growth potential of leukemia blast cells is associated with poor prognosis in human acute leukemias
(2009-12-29)
Abstract
We have described a severe combined immunodeficiency (SCID) mouse model that permits the subcutaneous growth of primary human acute leukemia blast cells into a measurable subcutaneous nodule which may be followed ...
Tocotrienols-induced inhibition of platelet thrombus formation and platelet aggregation in stenosed canine coronary arteries.
(2011-04-14)
Abstract
Background
Dietary supplementation with tocotrienols has been shown to decrease the risk of coronary artery disease. Tocotrienols are plant-derived forms of vitamin E, which have potent anti-inflammatory, ...
Serum proteomic profiling and haptoglobin polymorphisms in patients with GVHD after allogeneic hematopoietic cell transplantation
(2009-04-20)
Abstract
We studied serum proteomic profiling in patients with graft versus host disease (GVHD) after allogeneic hematopoietic cell transplantation (allo-HCT) by two-dimensional gel electrophoresis ...
One-year health status outcomes of unstable angina versus myocardial infarction: a prospective, observational cohort study of ACS survivors
(2007-09-12)
Abstract
Background
Unstable angina (UA) patients have lower mortality and reinfarction risks than ST-elevation (STEMI) or non-ST elevation myocardial infarction (NSTEMI) patients ...
Gene selection for classification of microarray data based on the Bayes error
(2007-10-03)
Abstract
Background
With DNA microarray data, selecting a compact subset of discriminative genes from thousands of genes is a ...
FEPI-MB: identifying SNPs-disease association using a Markov Blanket-based approach
(2011-11-24)
Abstract
Background
The interactions among genetic factors related to diseases are called epistasis. With the availability of ...
Investigation of 95 variants identified in a genome-wide study for association with mortality after acute coronary syndrome
(2011-09-29)
Abstract
Background
Genome-wide association studies (GWAS) have identified new candidate genes for the occurrence of acute coronary syndrome (ACS), but possible effects of such genes on survival following ACS ...
Testing the performance of the ENRICHD Social Support Instrument in cardiac patients
(2004-05-13)
Abstract
Background
Previous investigations suggest an important role of social support in the outcomes of patients treated ...
Neoadjuvant treatment of Dermatofibrosarcoma Protuberans of pancreas with Imatinib: case report and systematic review of literature
(2014-08-06)
Abstract
Dermatofibrosarcoma Protuberans (DFSP) is a rare skin tumor, characterized by frequent local recurrence but is seldom metastatic. It is histologically characterized by storiform arrangement of spindle ...
Recurrent acute pancreatitis and massive hemorrhagic ascites secondary to a duodenal duplication in a child: a case report
(2013-03-14)
Abstract
Introduction
Duodenal duplication is a rare congenital malformation and has been reported as a rare cause of recurrent acute pancreatitis. Hemorrhagic ascites has been reported in only ...
Regional pulse wave velocities and their cardiovascular risk factors among healthy middle-aged men: a cross-sectional population-based study
(2014-01-13)
Abstract
Background
Both carotid-femoral (cf) pulse wave velocity (PWV) and brachial-ankle (ba) PWV employ arterial sites that are not consistent with the path of blood flow. Few previous ...
Suppression of nitric oxide induction and pro-inflammatory cytokines by novel proteasome inhibitors in various experimental models
(2011-10-12)
Abstract
Background
Inflammation has been implicated in a variety of diseases associated with ageing, including cancer, cardiovascular, and neurologic diseases. We have recently established that the proteasome ...
Inhibition of nitric oxide in LPS-stimulated macrophages of young and senescent mice by delta-tocotrienol and quercetin.
(2011-12-20)
Abstract
Background
Changes in immune function believed to contribute to a variety of age-related diseases have been associated with increased production of nitric oxide (NO). We have recently reported that ...