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Sympathetic control of the collateral circulation : effects of time post-occlusion and exercise training
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] These studies evaluated the role of alpha-adrenergic receptors ([alpha]AR) and NPYergic receptors in the collateral circulation following acute and ...
Post-angioplasty restenosis : the effects of exercise training
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Percutaneous transluminal coronary angioplasty (PTCA) stimulates vascular cell proliferation and migration resulting in restenosis of the revascularized ...
Inhibition of progestin-induced VEGF in mammary cancer by curcumin and 2-methoxy estradiol and their potential role as anti-angiogenic & chemopreventive compounds
(University of Missouri--Columbia, 2009)
Estrogen/Progestin combined hormone replacement therapy (HRT) is commonly prescribed to alleviate the symptoms of menopause in women. Combination HRT however is associated with an increased risk of breast cancer, an effect ...
Comprehensive characterization of canine meniscal pathology
(University of Missouri--Columbia, 2010)
Meniscal injury is one of the most common causes of pain and dysfunction in the human knee and canine stifle joint. In the canine patient, meniscal injury is usually secondary to cranial cruciate ligament rupture, and the ...
Comparative imaging of canine shoulder osteochondrosis lesions
(University of Missouri--Columbia, 2010)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Over the last several years, papers have been published describing imaging techniques for the canine shoulder joint using both ultrasound and magnetic ...
Immunomodulatory effects of opioids
(University of Missouri--Columbia, 2010)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Opioids have been shown to modulate the immune system in animal models by affecting both the acquired and innate arms of the immune system. Many of ...
Modulation of the ACTH response to stress by IL-6, nitric oxide, diet and exercise
(University of Missouri--Columbia, 2006)
The release of ACTH from the anterior pituitary is one step in the activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is activated in response to stress and the secretion of ACTH is under the control ...
The cystic fibrosis transmembrane conductance regulator and acid-base transporters of the murine duodenum
(University of Missouri--Columbia, 2006)
The alkaline mucus barrier of the duodenum plays an important role in protecting the epithelium from acidic chyme entering from the stomach. Active HCO₃⁻ secretion involves the apical membrane activities of the cystic ...
Sensory integration during blood loss in conscious rabbits
(University of Missouri--Columbia, 2006)
Central nervous system integration of sensory inputs is critical for orchestrating physiological responses to stress. The focus of my doctoral research was investigating the physiological consequences of sensory stimulation ...
The effect of free fatty acids on endothelial cells
(University of Missouri--Columbia, 2005)
The purpose of this thesis was to determine if specific components of oxidized low density lipoprotein (OxLDL) molecules e.g. oxidized polyunsaturated fatty acids (PUFAs), or saturated free fatty acids (FFA) are alone ...
Examination of nucleus accumbens mechanisms underlying the motivation for physical activity
(University of Missouri--Columbia, 2017)
Physical inactivity, a primary contributor to numerous diseases including obesity, type 2 diabetes, depression, and dementia, has reached pandemic levels worldwide. Alarmingly, the percentage of individuals engaging in ...
Cardiorespiratory fitness through the early lifecourse and attempts to modulate its initial decline
(University of Missouri--Columbia, 2015)
There has never been an outcome measure for human health more important than VO2peak, yet we know nothing about the molecular triggers for its decline with aging. Peak aerobic capacity (VO2peak) is a strong predictor of ...
Hyperglycemia and type 2 diabetes : impact on neural cardiovascular control
(University of Missouri--Columbia, 2015)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Type 2 diabetes (T2D) is often characterized by chronic hypertension and exaggerated increases in arterial blood pressure (BP) during exercise. However, ...
Prevalence of Staphylococcus aureus and MRSA carriage in three populations
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] A higher prevalence of methicillin-resistant Staphylococcus aureus (MRSA) colonization has been reported in healthcare workers than in non-healthcare ...
Estrogen receptor [alpha] and [beta] knock-out effects on skeletal muscle in mature female and male mice, and aromatase knock-out effects on skeletal muscle in mature male mice
(University of Missouri--Columbia, 2007)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Estrogen regulates skeletal muscle mass and function in female. Estrogen may influence skeletal muscle mass and function during development in males ...
Clinical and treatment perspectives for heart failure with preserved ejection fraction /
(University of Missouri--Columbia, 2016)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Heart failure with preserved ejection fraction (HFpEF) currently represents half of the ~6 million heart failure patients in the United States, and is ...
Hyperproliferation and altered Wnt signaling in the cystic fibrosis mouse intestine /
(University of Missouri--Columbia, 2016)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis membrane conductance regulator (CFTR), a Cl- and HCO3 - channel expressed in several ...
The use of magnetic resonance imaging and proton spectroscopy to identify critical tissues in dogs with Duchenne Muscular Dystrophy for future assessment of therapeutic intervention : a pilot study
(University of Missouri--Columbia, 2018)
Duchenne's Muscular Dystrophy is a debilitating disease that affects skeletal and cardiac muscle of 1 in 5000 male births. In the last thirty years, the gene responsible for the encoding of Dystrophin has been identified, ...
A novel approach to the clinical diagnosis and treatment of canine histiocytic sarcoma
(University of Missouri--Columbia, 2017)
This work provides a review of canine histiocytic sarcoma (HS) including background immunology, diagnosis, treatment, and prognosis. Given the poor prognosis of HS compared to other soft tissue sarcomas in dogs, the research ...
Essays in corporate finance /
(University of Missouri--Columbia, 2016)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] [1] NEW CLASSIFICATIONS FOR CHAIRMEN OF THE BOARD -- I DID IT MY WAY. In this paper I determine whether a new classification of chairmen (former CEOs) ...