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Now showing items 21-40 of 6928
What is the best way to manage GERD symptoms in the elderly?
(Family Physicians Inquiries Network, 2006)
No evidence supports one method over another in managing uncomplicated gastroesophageal reflux disease (GERD) for patients aged >65 years. For those with endoscopically documented esophagitis, proton pump inhibitors (PPIs) relieve symptoms faster...
Which drugs are best when aggressive Alzheimer's patients need medication?
(Family Physicians Inquiries Network, 2010)
controlled trials [RCTs]). However, evidence of drug-related deaths in patients taking these drugs mandates weighing the benefits against the risks. SSRIs may be a safer, effective alternative (SOR: B, limited studies). Evidence for the efficacy...
Management of ADHD in preschool-aged children
(Family Physicians Inquiries Network, 2013)
RCTs.) Alternative therapies, such as elimination diets, have limited evidence of success and should generally be avoided or used in conjunction with standard therapies. (SOR: B, based on a systematic review of a small number of heterogeneous RCTs.)...
Is there benefit to adding ezetimibe to a statin for the secondary prevention of CVD?
(Family Physicians Inquiries Network, 2023-06)
Q: Is there benefit to adding ezetimibe to a statin for the secondary prevention of CVD? Evidence-based answer: YES. In patients with known cardiovascular disease (CVD), ezetimibe with a statin decreases major adverse cardiovascular events (MACE...
How do hyaluronic acid and corticosteroid injections compare for knee OA relief?
(Family Physicians Inquiries Network, 2017)
for symptomatic knee osteoarthritis (OA), but that insufficient evidence exists to recommend HA injections (SOR: B, evidence-based guidelines)....
Pharmacologic therapy for eustachian tube dysfunction
(Family Physicians Inquiries Network, 2013)
There are no medications that improve patient-oriented outcomes in children or adults with eustachian tube dysfunction. (Strength of Recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs].) Oral corticosteroids...
What's the best test for underlying osteomyelitis in patients with diabetic foot ulcers?
(Family Physicians Inquiries Network, 2015)
, evidence-based guidelines)....
Longitudinal, naturalistic study of training and support for implementation of evidence-based youth mental health practices among community providers
(University of Missouri--Columbia, 2021)
support in evidence-based practices (EBPs). To address this need, the current study describes the reach and impact of a county-wide youth MH initiative aimed at increasing youths' and families' access to effective youth MH services by providing free EBP...
Does birth weight predict childhood obesity?
(Family Physicians Inquiries Network, 2008)
A birth weight greater than 4,000 g is associated with an increased risk of obesity in both childhood and adolescence (strength of recommendation [SOR]: B, systematic review and multiple cohort studies).
How effectively do ACE inhibitors and ARBs prevent migraines?
(Family Physicians Inquiries Network, 2018)
Q: How effectively do ACE inhibitors and ARBs prevent migraines? Evidence-based answer: The angiotensin-converting enzyme (ACE) inhibitor lisinopril reduces the number of migraines by about 1.5 per month in patients experiencing 2 to 6 migraines...
What is the prognosis of postherpetic neuralgia?
(Family Physicians Inquiries Network, 2003)
, based on a well-done prospective cohort study)....
Prescribe an SGLT2 inhibitor for heart failure in the absence of diabetes?
(Family Physicians Inquiries Network, 2021)
Prescribe an SGLT2 inhibitor for heart failure in the absence of diabetes? An RCT demonstrates that dapagliflozin produces better cardiovascular outcomes than placebo for heart failure patients with and without diabetes. PRACTICE CHANGER: Prescribe...
Is intra-articular platelet-rich plasma injection an effective treatment for knee OA?
(Family Physicians Inquiries Network, 2019)
Q: Is intra-articular platelet-rich plasma injection an effective treatment for knee OA? EVIDENCE-BASED ANSWER: PROBABLY NOT, based on the balance of evidence. While low-quality evidence may suggest potential benefit, the balance of evidence...
What is the long-term educational outlook for youngsters with ADHD?
(Family Physicians Inquiries Network, 2011)
tend to underperform in both educational and occupational settings (strength of recommendation: A, 2 prospective cohort studies and a case control study). These findings are based solely on patients with ADHD who were referred to psychiatric clinics...
Q: Is event-driven PrEP dosing for HIV as effective as daily dosing?
(Family Physicians Inquiries Network, 2021-06)
Evidence based answer: PROBABLY, although there are no head-to-head trials comparing the 2 dosing regimens. Event-driven pre-exposure prophylaxis (PrEP) dosing reduces HIV conversion by 86% compared to placebo (strength of recommendation [SOR]: B...
How should we use the coronary artery calcium score to predict cardiovascular risk?
(Family Physicians Inquiries Network, 2011)
The coronary artery calcium (CAC) score--an independent predictor of cardiovascular events (strength of recommendation [SOR]: C, systematic review of disease-oriented outcomes)--can be used, in addition to traditional risk ...
Statin Therapy in Patients with Type 2 Diabetes
(Family Physicians Inquiries Network, 2005)
Based on current evidence, statin therapy should be offered to all patients with type 2 diabetes who are known to have coronary artery disease. [Strength of recommendation: A] For patients older than 40 years with type 2 diabetes who are not known...
What is appropriate fetal surveillance for women with diet-controlled gestational diabetes?
(Family Physicians Inquiries Network, 2006)
No evidence clearly supports the practice of increased fetal surveillance in the pregnancies of women with well-controlled (ie, fasting blood sugar <105 mg/dL) class A1 gestational diabetes (strength of recommendation [SOR]: B, consistent...
Screening for hepatocellular carcinoma in patients with hepatitis C virus infection
(Family Physicians Inquiries Network, 2013)
There is no evidence that it is beneficial to screen for hepatocellular carcinoma in symptomatic patients with HCV. (Strength of Recommendation [SOR]: C, based on a systematic review and case series studies.) Neither serum AFP measurement nor...
Treatment-Resistant Depression Diagnosis in the Outpatient Behavioral Health Setting
(University of Missouri -- Kansas City, 2023)
Treatment-resistant depression can be challenging to identify in the outpatient behavioral health setting due to a lack of clear diagnostic guidelines. The evidence-based quality improvement project examined current practices in diagnosing treatment...