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Tnf[alpha] alters occludin and endothelial cell barrier function : role of p38MAPK
(University of Missouri--Columbia, 2016)
Occludin is one of the key tight junction (TJ) proteins in endothelial cells and it plays an important role in modulating blood brain barrier (BBB) function. This protein (65kDa) has been shown to engage in many signaling ...
Fabrication and characterization of a plasmonic grating platform for enhanced fluorescence biosensor applications
(University of Missouri--Columbia, 2016)
Surface plasmon resonance (SPR) research has grown substantially over the past several years and led to many substantial discoveries in nanotechnology. SPR is a phenomenon where light can be coupled to the interface between ...
Automatic four-limb IMU gait analysis in the canine DMD model
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Gait analysis is valuable for studying neuromuscular and skeletal diseases. Wearable motion sensors or inertial measurement units (IMUs) possess ...
Investigation of supercritical water processing of biomass : study of high pressure separation
(University of Missouri--Columbia, 2016)
Global warming is caused by greenhouse gases such as CO2, CH4, NOx, and SOx. CO2 makes up about 80% (by mass) of greenhouse gas emitted by human activities. Therefore, CO2 emission plays a significant role in global warming. ...
Rapid detection and characterization of mycobacteria using microchannel electrical impedance spectroscopy
(University of Missouri--Columbia, 2017)
The presence of virulent, pathogenic bacteria in our body, food, water and other consumables is harmful and causes enormous economic and personal losses. Here we will be looking at developing a platform technology that can ...
Paraxial application of auxiliary devices with waveguide mediated laser irradiation for applications in medical biophotonics
(University of Missouri--Columbia, 2017)
Laser-based medical applications offer minimally-invasive alternatives to traditional procedures; however, the simplistic method of open-air laser transmission poses ocular hazards and negative side effects, along with a ...
Studying pupillary light reflex in young children with autism spectrum disorders
(University of Missouri--Columbia, 2016)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Pupillary light reflex (PLR) is a phenomenon wherein the pupil size changes according to retina illumination. PLR of adults and children has been ...
Climate change impacts on hydrologic components and occurrence of drought in an agricultural watershed
(University of Missouri--Columbia, 2018)
The study on potential acceleration of future hydrologic cycle due to change in precipitation and increase in temperature are essential for managing natural resources and setting policy. The impact of future climate change ...
Evaluation of a solid-liquid manure separation operation
(University of Missouri--Columbia, 2018)
Field monitoring and laboratory tests were conducted to evaluate the efficacy and practicality of a solid-liquid separation barn for finishing pigs. The solid-liquid separation system included a mechanical scraper and ...
Imaging fiber orientation in articular cartilage using optical polarization tractography
(University of Missouri--Columbia, 2016)
Articular cartilage plays a vital role in providing a low-friction surface between the bones of joints. This mechanical function is highly related to the special collagen organization in cartilage, especially in the ...
Evaluating removal of nutrients, volatile organic compounds, and nicotine by bioretention soil mixtures with biochar amendment
(University of Missouri--Columbia, 2016)
Urbanization results in reduced infiltration contributing to potential urban flooding and stormwater contaminants. Urban stormwater pollutants, including total suspended solids (TSS), nutrients, heavy metals, oil and grease ...
Design and characterization of a hand-held, waveguide-mediated, optoacoustic imaging probe for analyzing burn wounds
(University of Missouri--Columbia, 2018)
Clinicians correctly diagnose only [about]66% of burn wounds, which may be in part due to the qualitative methods commonly employed for burn assessment. This often results in over diagnoses, which may lead to unnecessary ...
Single nucleotide polymorphism (SNP) discriminations by nanopore sensing
(University of Missouri--Columbia, 2018)
Single Nucleotide Polymorphisms (SNPs) are a common type of nucleotide alterations across the genome. A rapid but accurate detection of individual or SNP panels can lead to the right and in-time treatments which possibly ...
In situ polymerizing collagen for the development of 3D printed tissue engineering scaffolds
(University of Missouri--Columbia, 2018)
Natural materials have been processed and utilized as scaffold materials in the field of tissue engineering for many years. One natural material often utilized is collagen since it is the main structural protein in mammalian ...
Between-row mower design for weed control in organically grown no-till soybeans
(University of Missouri--Columbia, 2018)
Weeds are a major challenge in organic no-till soybean production. They impair crop growth and result in yield loss. Innovative weed control methods need to be developed and experimented with in organic no-till agriculture ...
Development of a multispectral sensor for crop canopy temperature measurement
(University of Missouri--Columbia, 2017)
The Multispectral System for Imaging of a Crop Canopy (MSICC) that combines a miniature long wavelength infrared (LWIR) camera with a visible camera was developed to capture a field of view and derive a plant specific ...
Modeling and optimization of the Mannheimia haemolytica vaccine production process
(University of Missouri--Columbia, 2017)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Leukotoxin (Lkt) from Mannheimia haemolytica has been discovered as the primary pathogenic factor for bovine respiratory disease (BRD), causing huge ...
Electrospinning lecithin-polycaprolactone scaffolds with gold nanoparticles for osteoarthritis prevention
(University of Missouri--Columbia, 2018)
The human body has articular cartilage covering the ends of the bones to act as a shock absorber and aid in movement. In a disease state, this articular cartilage breaks down causing pain, swelling, and stiffness. With ...
Clinical translation of nanomaterials for early detection of genetic abnormalities in fetus and retinopathy in neonates and adults
(University of Missouri--Columbia, 2017)
Nuclear medicine covers a wide variety of radionuclides to meet demands of disease. In the current study, first we have looked at the application of mono-amine mono-amide ligands for Re(V), 99mTc(V), and 186Re(V) with ...
Knee contact force prediction during a step-up task using a subject specific musculoskeletal model with anatomical knee
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Better understanding of knee mechanics can aid in injury prevention and rehabilitation. Multi-body computational models can be used to better understand ...