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Amyloid- [beta] peptide induces temporal membrane biphasic changes in astrocytes through cytosolic phospholipase A₂
(University of Missouri--Columbia, 2010)
Oligomeric amyloid-[beta] peptide (A[beta]) is known to induce cytotoxic effects and damage cell functions in Alzheimer's disease. However, mechanisms underlying the effects of A[beta] on cell membranes have yet to be fully ...
Functional study of Kcv potassium channel through manipultion [sic] of individual subunits
(University of Missouri--Columbia, 2010)
Potassium channels make up a ubiquitous, physiologically essential class of integral membrane proteins. Many K+ channels contain four identical symmetrically associated subunits. To explore the role of an individual subunit ...
Development of a fluorescence-based protease biosensor using nanoscale platforms
(University of Missouri--Columbia, 2010)
The development of a protease biosensor utilizing nanomaterials is presented in this dissertation. Peptide substrates and nanomaterial platforms were investigated to increase the sensitivity and response time for the ...
Development of an online planning tool for designing terrace layouts
(University of Missouri--Columbia, 2010)
A web-based conservation planning tool for terrace layouts was created by modifying a terrace location program (TERLOC), developed originally by Sudduth and Gregory (1982) and revised by Ghidey et al. (1992). Development ...
Development of land-use map for Salt River basin using satellite imagery
(University of Missouri--Columbia, 2010)
The Salt River Basin in northeastern Missouri is the major water supply source for people in the region. There is a need to build a long term simulation and to validate the long term trend of pollutant concentrations in ...
Development of a biosensor for the detection of Helicobacter hepaticus utilizing multi-functioning immobilization platforms
(University of Missouri--Columbia, 2010)
Optical biosensor development is a process involving the careful selection of the material for the immobilization platform, design of the detection mechanism and integration with optical and electronic equipment. The ability ...
Applications of the opto-fluidic ring resonator for DNA methylation analysis and microfluidic laser development
(University of Missouri--Columbia, 2010)
For several decades, optical ring resonators have played an important role in the field of telecommunications. Within only the past decade however, ring resonators have been applied for the purposes of biological and ...
Molecularly imprinted polymer labeled with quantum dots for detection of nitroaromatic explosives
(University of Missouri--Columbia, 2010)
A sensing device for explosive compounds is a fundamental step towards the capability to detect the presence of landmines, improvised explosive devices (IEDs), and other unexploded ordinance. To detect high explosive ...
Regional heterogeneity of adventitial elastin in the arteriolar wall reflects differences in the mechanical environment
(University of Missouri--Columbia, 2011)
Adventitial elastin provides structural and mechanical support for arterioles. While elastin quantities are known in arterioles, the structure of elastin fibers and distribution of elastin throughout the vessel was unknown. ...
Photoacoustic detection and spectral analysis of hemozoin in human leukocytes as an early indicator of malaria infection
(University of Missouri--Columbia, 2011)
Malaria is a blood borne infection affecting hundreds of millions of people worldwide. Usually, malaria is diagnosed only after a patient presents symptoms, including high fever, nausea, and, in advanced cases, coma and ...
Time delay compensation in finite-order models of acoustic wave propagation in homogenous media
(University of Missouri--Columbia, 2011)
Finite-order models do not completely account for the delay in acoustic wave propagation and thus require an additional phase correction, besides parameter adjustments to fit experimental measurements. As a consequence, ...
Exploration of supercritical water gasification of biomass using batch reactor
(University of Missouri--Columbia, 2011)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The focus of this study is on gasification of a biomass in supercritical water. Vapor mass yield in a batch reactor after 20 minutes in a 700[degrees]C ...
Manure management using precision agriculture
(University of Missouri--Columbia, 2010)
The overall purpose of this project was to develop and implement a manure application record system that was solely based on Global Positioning Systems (GPS). This system will have the ability to provide steering and ...
Geographic information systems used for precision agriculture : knowledge and use by agriculture students at the University of Missouri (MU)
(University of Missouri--Columbia, 2010)
The use of GIS in PA technology helps manage the information intensive environment in production agriculture by intertwining site-specific (within field) management with computer software modeling for analyses and ...
Switchgrass production in the central claypan region of Missouri
(University of Missouri--Columbia, 2010)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Severe soil erosion across the Central Claypan Region of Missouri has been correlated with low productivity as the depth to the claypan horizon ...
Microfluidic capture of rare cells via non-cylindrical microposts in an array
(University of Missouri--Columbia, 2014)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] In recent decades, microsystems for the capture of rare cells have become exceedingly popular and important in the study of cellular mechanisms. These ...
Soil property estimation using visible and near-infrared reflectance
(University of Missouri--Columbia, 2012)
Site-specific management of crop production systems holds promise for maintaining high yields while preserving soil quality. This management requires detailed spatial data on soil physical and chemical characteristics but ...
Characterizing optical properties in fibrous tissues
(University of Missouri--Columbia, 2011)
Optical methods are promising for non-invasive tissue characterization. Biological tissues can be classified into isotropic tissues and anisotropic tissues. The optical properties of isotropic tissues such as adipose tissue ...
Porous silicates for applications in smart water treatment systems and antimicrobial biomedical coatings
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Porous silicates, particularly ordered ones, may find novel and wide-ranging applications in the bioengineering arena in the near future. For instance, ...
A continuous-wave-based acoustic method to measure viscoelastic properties of materials
(University of Missouri--Columbia, 2017)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Typical viscoelastic materials do not have a flat frequency response to mechanical vibrations. Viscoelastic property evaluations with a multi-frequency ...