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Now showing items 21-40 of 1758
What are the indications for treatment with angiotensin-converting enzyme (ACE) inhibitors in patients with diabetes?
(Family Physicians Inquiries Network, 2001)
of recommendation: A, based on randomized controlled trials.)...
Should the varicella vaccine be given to all children to prevent chickenpox?
(Family Physicians Inquiries Network, 2004)
Healthy, unimmunized children who have not had varicella infection should be vaccinated (strength of recommendation: A, based on randomized controlled trials). Use of the vaccine in immunocompromised children is still being studied and has not been...
Is the ThinPrep better than conventional Pap smear at detecting cervical cancer?
(Family Physicians Inquiries Network, 2004)
the conventional Papanicolaou (Pap) smear at detecting cervical cancer (strength of recommendation [SOR]: A-, based on 1 large validating cohort study with a good reference standard and 1 systematic review). There is insufficient evidence to recommend 1 preparation...
Does ambulatory blood pressure monitoring aid in the management of patients with hypertension?
(Family Physicians Inquiries Network, 2002)
Twenty-four hour ambulatory blood pressure monitoring (ABPM) has a higher correlation with target end-organ damage than standard office measurements and is superior for risk stratification. Because it is more complicated to implement than office-based...
How should a DEXA scan be used to evaluate bisphosphonate therapy for osteoporosis?
(Family Physicians Inquiries Network, 2005)
If bone density is evaluated after initiating bisphosphonate drug therapy, it should be tested no earlier than 2 years (strength of recommendation [SOR]: B, based on case series of dual energy x-ray absorptiometry [DEXA] scanning precision...
Which detoxification regimens are effective for alcohol withdrawal syndrome?
(Family Physicians Inquiries Network, 2021)
Q: Which detoxification regimens are effective for alcohol withdrawal syndrom? Evidence based answer: Benzodiazepines remain the first-line regimen for alcohol withdrawal syndrome (AWS) and are the only class more effective than placebo for reducing...
Do oral contraceptives carry a significant risk of stroke for women with migranes?
(Family Physicians Inquiries Network, 2013)
Evidence-based answer: Estrogen-containing oral contraceptives may raise the risk of ischemic stroke in women with migraine, particularly migraine with aura (strength of recommendation [SOR]: C, small case-control studies with methodological flaws...
Does turmeric relieve inflammatory conditions?
(Family Physicians Inquiries Network, 2011)
Limited evidence suggests that turmeric and its active compound, curcumin, are effective for rheumatoid arthritis and other inflammatory conditions (strength of recommendation [SOR]: C, primarily low-quality cohort studies with small patient numbers...
How useful is high-sensitivity CRP as a risk factor for coronary artery disease?
(Family Physicians Inquiries Network, 2005)
risk for cardiovascular disease, with some evidence suggesting its use if the results of the test will alter treatment recommendations (strength of recommendation [SOR]: C, based on extrapolation of consistent level 2 studies). Research to date...
What medication best prevents migraine in children?
(Family Physicians Inquiries Network, 2003)
controlled trial, prospective or retrospective cohort studies, or trials with conflicting evidence). Flunarizine and nimodipine have the best evidence of benefit in children; however, availability, cost, and side effects limit their usefulness (SOR: B, based...
Antibiotic Prophylaxis to Prevent Recurrent UTI in Children
(Family Physicians Inquiries Network, 2011)
Antibiotic prophylaxis to prevent recurrent UTI may be considered in infants and children with or without vesicoureteral reflux (VUR) after a first UTI. (Strength of Recommendation [SOR]: B, based on inconsistent evidence from systematic reviews...
Best Alternatives to Statins for Treating Hyperlipidemia
(Family Physicians Inquiries Network, 2007)
but not total mortality. (SOR: A, based on review of RCTs). The effects of ezetimibe (Zetia) on cardiovascular outcomes and mortality are unknown. (SOR: C, based on a single RCT with disease-oriented evidence). Omega-3 fatty acid supplementation does not clearly...
What's the best secondary treatment for patients who fail initial triple therapy for H pylori?
(Family Physicians Inquiries Network, 2018)
Q: What's the best secondary treatment for patients who fail initial triple therapy for H pylori? Evidence-based answer: treating patients with Helicobacter pylori infection who have failed clarithromycin-based triple therapy with either...
Does moderate exercise prevent MI for patients with coronary heart disease?
(Family Physicians Inquiries Network, 2004)
Moderate exercise reduces mortality for patients with known coronary heart disease but does not significantly decrease the risk of recurrent nonfatal myocardial infarction (MI) (strength of recommendation [SOR]: A, based on systematic review...
What predicts a successful smoking cessation attempt?
(Family Physicians Inquiries Network, 2006)
Quit date abstinence (strength of recommendation [SOR]: B, based on low-quality randomized controlled trial [RCT] of healthy subjects) and refraining from tobacco products within the first 2 weeks after an attempt (SOR: A, based on 2 RCTs) predict...
What is the best therapy for constipation in infants?
(Family Physicians Inquiries Network, 2002)
The best treatment for minor, self-limited constipation (infant dyschezia) may be observation and parental education about its benign nature. (Grade of recommendation: D, expert opinion.) For cases requiring treatment, limited evidence suggests...
Is there a role for theophylline in treating patients with asthma?
(Family Physicians Inquiries Network, 2002)
asthma attacks. Side effects and toxicity limit use of these medications in most settings. (Grade of recommendation: A, based on systematic reviews and randomized control trials [RCTs])....
Q Is exercise therapy effective treatment for low back pain?
(Family Physicians Inquiries Network, 2021-11)
Evidence-based answer: Yes, it is somewhat effective. Exercise therapy—including general exercise, yoga, Pilates, and motor control exercise—has been shown to modestly decrease pain in chronic low back pain (LBP); levels of benefit in short...
Does screening by primary care providers effectively detect melanoma and other skin cancers?
(Family Physicians Inquiries Network, 2020)
Q: Does screening by primary care providers effectively detect melanoma and other skin cancers? Evidence-based answer: possibly. No trials have directly assessed detection of melanoma and other skin cancers by primary care providers. Training a...
Does breastfeeding protect against viral GI infections in children <2 years old?
(Family Physicians Inquiries Network, 2003)
While breastfeeding protects against all-cause diarrhea in infants (strength of recommendation [SOR]: B, based on cohort studies and 1 randomized controlled trial), no evidence shows that breastfeeding confers specific protection against viral...