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Now showing items 61-80 of 7401
Does concurrent use of clopidogrel and PPIs increase CV risk in patients with ACS?
(Family Physicians Inquiries Network, 2020)
Q: Does concurrent use of clopidogrel and PPIs increase CV risk in patients with ACS? Evidence-based answer: No. Adding a proton pump inhibitor (PPI) in patients taking antiplatelet medications such as clopidogrel for acute coronary syndrome (ACS...
Do patients at high risk of Alzheimer's disease benefit from early treatment?
(Family Physicians Inquiries Network, 2009)
Treating patients with early-stage Alzheimer's disease yields statistically significant, though perhaps not clinically significant, improvement in cognition and global function (strength of recommendation [SOR]: A, consistent evidence from multiple...
Do complementary agents lower HbA1c when used with standard type 2 diabetes therapy?
(Family Physicians Inquiries Network, 2014)
Q. Do complementary agents lower HbA1c when used with standard type 2 diabetes therapy? A. No, there is no high-quality evidence that supports using complementary or alternative agents to lower hemoglobin A1c (HbA1c) in patients with noninsulin...
Nitroprusside cost reduction
(University of Missouri--Columbia., 2016)
"To decrease the cost of dispensed nitroprusside from MUHC inpatient pharmacy by at least 25 percent by 4/4/2016."--Aim statement.
Should a nylon brush be used for Pap smears from pregnant women?
(Family Physicians Inquiries Network, 2005)
most likely to be cost-effective. However, current evidence does not support any superiority of the nylon brush with spatula for any patient-oriented outcomes (eg, fewer procedures, less cancer, etc) during or after pregnancy (strength of recommendation...
Whom should you test for secondary causes of hypertension?
(Family Physicians Inquiries Network, 2014)
Evidence-based answer: It's recommended that all children and adolescents with a new diagnosis of hypertension undergo renal ultrasound and laboratory evaluation for renal pathology (strength of recommendation [SOR]: C, consensus-based guidelines...
Can CBT effectively treat adult insomnia disorder?
(Family Physicians Inquiries Network, 2018)
Q: Can CBT effectively treat adult insomnia disorder? Evidence-based answer: Yes. Cognitive behavioral therapy (CBT) administered individually, in a group setting, or on the internet is effective for treating insomnia in adults compared with control...
What treatments work best for constipation in children?
(Family Physicians Inquiries Network, 2009)
limited evidence supports this approach (strength of recommendation [SOR]: B for fiber, 1 randomized controlled trial [RCT]; C for behavior modification, 1 small trial). For pharmacologic management, the best evidence supports osmotic laxatives (SOR: A, 6...
Do A-fib patients continue to benefit from vitamin K antagonists with advancing age?
(Family Physicians Inquiries Network, 2019)
Q Do A-fib patients continue to benefit from vitamin K antagonists with advancing age? Evidence-based answer: yes, patients with atrial fibrillation who are between the ages of 50 and 90 years continue to benefit from vitamin K antagonist therapy...
What medical therapies work for gastroparesis?
(Family Physicians Inquiries Network, 2018)
Q: What medical therapies work for gastroparesis? Evidence-based answer: It's unclear if there are any highly effective medications for gastroparesis (TABLE1-10). Metoclopramide improves the sense of fullness by about 40% for as long as 3 weeks, may...
What are the benefits/risks of giving betamethasone to women at risk of late preterm labor?
(Family Physicians Inquiries Network, 2018)
Q: What are the benefits/risks of giving betamethasone to women at risk of late preterm labor? Evidence-based answer: Giving betamethasone to women at risk for delivery between 34 weeks 0 days and 36 weeks 6 days can lower by almost 40...
What is the best strategy for monitoring the lipid-lowering effects of medical therapy used for the primary prevention of coronary artery disease (CAD)?
(Family Physicians Inquiries Network, 2001)
There is good evidence that treatment for primary prevention of CAD decreases risk of major first coronary events and cardiovascular mortality, though all-cause mortality has not been shown to be reduced. There is no evidence identifying the best...
How effective is gastric bypass for weight loss?
(Family Physicians Inquiries Network, 2004)
Gastric bypass results in weight loss of approximately 33% at 2 years and 25% at 8 years (strength of recommendation [SOR]: B, based on a cohort study). Gastric bypass is one type of bariatric surgery, which also includes gastroplasty and gastric...
Is this pregnancy viable?
(Family Physicians Inquiries Network, 2013)
of recommendation: A: Based on a systematic review and meta-analysis of 26 diagnostic accuracy studies....
Does caffeine intake during pregnancy affect birth weight?
(Family Physicians Inquiries Network, 2016)
Q: Does caffeine intake during pregnancy affect birth weight? Evidence-based answer: No. Reducing caffeinated coffee consumption by 180 mg of caffeine (the equivalent of 2 cups) per day after 16 weeks-gestation doesn't affect birth weight. Consuming...
Does office spirometry improve quit rates in smokers?
(Family Physicians Inquiries Network, 2010)
Simply performing spirometry and offering cessation advice doesn't improve quit rates in patients who smoke (strength of recommendation [SOR]: A, systematic review of randomized controlled trials [RCTs]). However, when the ...
Prescribing an antibiotic? Pair it with probiotics
(Family Physicians Inquiries Network, 2013)
Recommend that patients taking antibiotics also take probiotics, which have been found to be effective both for the prevention and treatment of antibiotic-associated diarrhea (AAD). Stength of recommendation: A: Based on a systematic review and meta...
Prescribe an SGLT2 inhibitor for heart failure in the absence of diabetes?
(Family Physicians Inquiries Network, 2021)
Prescribe an SGLT2 inhibitor for heart failure in the absence of diabetes? An RCT demonstrates that dapagliflozin produces better cardiovascular outcomes than placebo for heart failure patients with and without diabetes. PRACTICE CHANGER: Prescribe...
Be my best foley friend!
(University of Missouri--Columbia., 2018)
"Our aim is to reduce catheter-associated urinary tract infections (CAUTI) that occur within 3-5 days post insertion by 10 percent by training select nurses in evidence based urinary catheter insertion techniques to be a Best Foley Friend (BFF...
What nonhormonal therapies are effective for postmenopausal vasomotor symptoms?
(Family Physicians Inquiries Network, 2003)
, and phenobarbital), methyldopa, evening primrose oil, maiquan, flaxseed, ginseng, and topical wild yam extract--have not been effective. Black cohosh may be effective, but the evidence for this is of poor quality (SOR: C)....