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Now showing items 61-80 of 107
Phosphinimines as potential technetium environmental sensors
(University of Missouri--Columbia, 2007)
-napthyl)Ph₂P=NSiMe₃ include possible reporter groups and (p-COOMe)C₆H₄Ph₂P=NSiMe₃ contains a linking moiety for incorporating reporter groups or attaching the phosphinimine to a polymer support. The use of internal and external reporter groups to generate...
Spectroscopic studies of transmembrane helical peptides and LC-MS/MS method development and validation for PFAS quantitation
(University of Missouri--Columbia, 2022)
Water hydrogen bonding (H-bonding) to [alpha]-helical transmembrane (TM) peptides is fundamental to understanding the behavior and function of [alpha]-helical peptides, disease pathways, and the development of new drugs. ...
Reactivity of lesions derived from abasic (AP) sites in DNA
(University of Missouri--Columbia, 2021)
damage and are present in steady state levels of 10,000 Ap sites per cell per day. These lesions have been studied in the past, but there is still much to know about these noxious, electrophilic lesions. This thesis attempts to use the tools of organic...
Ammonia elimination from protonated nucleobases
(University of Missouri--Columbia, 2007)
The dediazoniations of the diazonium ion 1 of 4-aminopyrimidine and of the tautomeric cytosinediazonium ions 2 and 3 are facile and result in the formations of cations 4, 5, and 6. The pyrimidine ring-opening of 4, 5 and ...
Computational studies of three chemical systems
(University of Missouri--Columbia, 2011)
on both the singlet and triplet PES. MP2 optimizations were used to identify minima and transition states. A series of CCSD(T) single-point calculations were used to extrapolate to the complete basis set limit....
The investigation of the self-assemblies of pyrogallol [4] arenes with large metal ions
(University of Missouri--Columbia, 2022)
on the interactions of pyrogallol[4]arene ligands with large metal ions. Interaction of C-ethylpyrogallol[4]arene with calcium ions led to the formation of two unprecedented dodecameric nanocapsules in the solid state with a large internal volume. Interaction of C...
Probing synthesis of L-ascorbic acid in Arabidopsis thaliana genotypes
(University of Missouri--Columbia, 2021)
L-Ascorbic acid (L-AsA), also known as vitamin C, is a crucial vitamin for both plants and animals due to its antioxidant properties and abilities to scavenge harmful reactive oxygen species (ROS). However, some animals ...
Rhenium complexes with O, N, S ligands
(University of Missouri--Columbia, 2006)
The main focus of this thesis is the synthesis and characterization of nonradioactive rhenium complexes containing O, N, S ligands. Chapter 2 describes the rhenium labeling of four somatostatin analogues. Confirmation for ...
Radioactive Au for potential radiotherapeutic application
(University of Missouri--Columbia, 2010)
Radioactive gold-198/199 can be used in therapeutic radiopharmaceutical agents to combat cancer. In this thesis, two projects involving the development of radioactive gold-198/199 are described. The first project discusses ...
Anisotropic organic materials : ferroelectric crystals and spin-polarized radicals
(University of Missouri--Columbia, 2007)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Anisotropic organic materials are attracting increasing interesting for their highly electro-optic characteristics. We are especially interested in ...
Determination of total selenium and seleno-amino acids in yeast and aquatic organisms by liquid chromatography and inductively coupled plasma mass spectrometry
(University of Missouri--Columbia, 2007)
The primary goal of this dissertation research was to develop methods for routine speciation analysis of selenium in tissues. A method for total selenium using on-line stable isotope dilution analysis with conventional ...
Systematic evaluation of the effects of ammonium-based deep eutectic solvent chemistry on the performance of dye-sensitized photovoltaic solar cells
(University of Missouri--Columbia, 2023)
The enthusiasm for renewable energy technologies is growing exponentially, with researchers from various fields actively engaged in the development of more sustainable and environmentally friendly solutions. Deep eutectic ...
Anion and solvent influences on the self-assembly of copper(I) coordination solids
(University of Missouri--Columbia, 2005)
The investigation of solvent and anion influences on the self-assembly of copper(I) coordination solids are presented. As these extended solids vary in structural design as reactions conditions are varied, both those ...
Investigation of the replacement of cysteine residues in DOTA-(Tyr³)-octreotate: synthesis, characterization and evaluation of biological activities
(University of Missouri--Columbia, 2006)
-DOTA-Tyr³-octreotate. IC₅₀ values of two peptides, nat[superscript]In-DOTA-̕ [DCys², Tyr³, DCys⁷]-octreotate and natIn-DOTA-̕[Pen², Tyr³, Pen⁷]-octreotate were in the range of 10-⁶-10-⁵ M range....
Radiotracers for examining biological functions of plants and microbes
(University of Missouri--Columbia, 2021)
Tracers are used for qualitative and quantitative investigation of a system. Radiotracers have a radionuclide to observe chemical or biological processes by detection of the radionuclide's decay energy. They are non-disruptive ...
Trithiol ligand development for radioarsenic and radioantimony toward potential theranostic radiopharmaceutical agents
(University of Missouri--Columbia, 2022)
Radiopharmaceuticals deliver radioactive drugs to specific target sites for imaging or therapy purposes, depending on the decay characteristics of the radionuclides. Potential radiopharmaceuticals are commonly designed via ...
Evaluating the suitability of the human toenail as a biomonitor for manganese status: the one source cohort
(University of Missouri--Columbia, 2007)
Numerous studies have demonstrated that the human toenail is a reliable biomonitor for the intake of Se and other elements. The objective of this study was to evaluate the hypothesis that Mn intake is reflected in toenail ...
Radionuclide production and separation techniques for radiopharmaceutical development and nuclear waste processing
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] With increasing cancer incident rates and advancements in nuclear medicine, the demand for optimizing pathways to produce radionuclides or investigating ...
Studies of the chemistry of Tröger's base, cyclopentadienones, and 2,1-benzothiazines
(University of Missouri--Columbia, 2006)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The sequential alkylation of Tröger's base was developed for the synthesis of symmetric dialkylation analogs. The products from this reaction were ...
High valent uranium dioxo and imido complexes : synthesis and structure
(University of Missouri--Columbia, 2008)
Early actinide elements have attracted considerable attention in recent years due to the need for rigorous advancements in spent nuclear fuel recycling and remediation technologies, and for their emerging versatility in ...