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The effect of caloric restriction on the mitotic rates of mice
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Caloric restriction has been shown to cause a number of biological changes in animals including the retardation of the aging process. Calorically- restricted animals show an average increase in life span of 30 - 50 %. In ...
A search for regulators of a yeast synaptojanin
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
The yeast S. cerevisiae expresses three synaptojanins: Inp51p, Inp52p, and Inp53p. These enzymes are characterized by two specific characteristics. They contain an inositol 5'-phosphatase and a polyphosphoinositide ...
The evolving technology of bio-printing
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Bio-printing is a novel method of tissue engineering that uses living cell spheroids as the 'bio-ink' and biocompatible gels as the 'bio-paper' with a three dimensional printer that deposits these aggregates into the gel ...
Point mutation of an RGD sequence in the human P2Y2 receptor to a QGD sequence conserves Go-mediated signal transduction
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
The P2Y2 nucleotide receptor is a Go/q coupled receptor that is activated equipotently by extracellular nucleotides such as ATP or UTP and is upregulated in a variety of tissues in response to injury or stress. The biological ...
Detection of Sad genes in various species of Neurospora
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Neurospora crassa is a haploid fungus that reproduces asexually during vegetative growth. However, in a nitrogen deficient environment, the two mating-type cells, A and a, can fuse together and enter the sexual cycle. ...
The effects of even-aged cutting on density and pairing success of Worm-eating Warblers
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
It is important for researchers to be aware of how timber management practices affect songbird populations. Certain forest management techniques can cause declines in breeding habitat of Neotropical migrant songbirds that ...
Localized adherence of Haemophilus influenzae to human lung cells in tissue culture
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
The gram-negative coccobacillus H. influenzae is part of the respiratory mucosal flora of most healthy humans. Before the era of Hib vaccination, encapsulated H. influenzae of serotype b were the leading cause of childhood ...
Expression, purification and initial characterization of Halobacterium proline dehydrogenase
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Nature recycles proline by converting it to glutamate. This 4-electron oxidation process is catalyzed by two catabolic enzymes, proline dehydrogenase (PRODH) and Δ1-pyrroline-5-carboxylate dehydrogenase (P5CDH). Inborn ...
Anti-galectin-3 peptides increase apoptosis in galectin-3 expressing human breast cancer cells
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
A critical factor in the proliferation and the metastatic nature of carcinoma cells appears to be their resistance to natural programmed cell death (apoptosis). However, the molecular mechanisms that enable carcinoma cells ...
Reduction of rheniumV oxo Schiff base complexes with triethylphosphine
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Pioneering techniques for therapeutic treatment of cancers involve targeting cancer sites with strong beta-emitting radionuclides, thereby destroying the cancer cells. This is achieved by coordinating the radioisotope to ...
Promotion of functional heterotrimeric type I collagen via transfection in osteogenesis imperfecta fibroblasts
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Osteogenesis imperfecta (OI) is a heritable disorder due to mutations in type I collagen. Normal type I collagen forms a heterotrimeric protein comprised of two pro1(I) chains and one pro2(I) chain [1(I)22(I)]. The ...
Molecular free volume and viscosity changes in non-Newtonian fluids probed with molecular rotors
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
An empirical relationship between molecular free volume and viscosity has been established (Doolittle AK, J Appl. Phys. 1952; 23: 236-9). Non-Newtonian fluids hold much importance to scientific study because of their ...
Reduction of rhenium (V) oxo Schiff Base Complexes with triphenyl phosphine ligands
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
One approach to the treatment of cancer is to direct beta-emitting radionuclide to the cancer site where the radiation destroys the cancer cells. This can be achieved by coordinating the radioisotope in a very stable ...
"Either he was too weak, or the world was too strong" : motifs of male wounds and healing in African American literature
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
African American men throughout history have tried to establish and define their identities, collectively and individually, beyond those formed, forced, and fashioned by western civilization. Consequently, they have inflicted ...
The role of Periostin in regulating the biomechanical properties of cushion tissue
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
During embryonic heart development the atrio-ventricular (AV) cushions swell and fuse to form the valves and septa of the adult heart. Initially, the cushions appear as swellings on the interior wall of the AV canal and ...
Issues with scale using very high resolution digital aerial photographs
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
This study involves the use of remote sensing equipment to observe plant communities. A remote sensor is any instrument that gathers information about an object or area from a distance. Advanced cameras, the most common ...
Identification of chloroplast DNA insertions in nuclear chromosomes of maize B73 line using the FISH procedure
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
It is known that chloroplast DNA can incorporate itself into the nuclear genome of plants. However, the sites of chloroplast (ct) DNA integration into chromosomes of maize have not yet been analyzed. This project is the ...
The psychosocial response to lymphedema
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Lymphedema, a life-altering disease, affects many breast cancer survivors throughout the world. Manifested as either an acute or chronic illness, lymphedema can occur at any time during and following post-breast cancer ...
Making the Cvt pathway/autophagy in vitro
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Autophagy, Greek for “self eating”, occurs in all eukaryotic cells to remove damaged or unwanted organelles or to provide a source of nutrients during starvation. In autophagy, a double membrane surrounds a cluster of ...
Modeling the flow of digesta through the ruminant reticulorumen
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
Ruminants possess a specialized gastrointestinal (GI) tract that enables them to efficiently digest fibrous feeds. The first stomach compartment of the ruminant GI tract, the reticulorumen (RR), is the site of most fiber ...