Shared more. Cited more. Safe forever.
    • advanced search
    • submit works
    • about
    • help
    • contact us
    • login
    View Item 
    •   MOspace Home
    • University of Missouri-Columbia
    • Office of Undergraduate Research (MU)
    • Undergraduate Research and Creative Achievements Forum (MU)
    • 2005 Summer Undergraduate Research and Creative Achievements Forum (MU)
    • View Item
    •   MOspace Home
    • University of Missouri-Columbia
    • Office of Undergraduate Research (MU)
    • Undergraduate Research and Creative Achievements Forum (MU)
    • 2005 Summer Undergraduate Research and Creative Achievements Forum (MU)
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.
    advanced searchsubmit worksabouthelpcontact us

    Browse

    All of MOspaceCommunities & CollectionsDate IssuedAuthor/ContributorTitleIdentifierThesis DepartmentThesis AdvisorThesis SemesterThis CollectionDate IssuedAuthor/ContributorTitleIdentifierThesis DepartmentThesis AdvisorThesis Semester

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular AuthorsStatistics by Referrer

    Development of a portable source for production of Re-188

    Rahing, Valerie
    Ketring, Alan R.
    Ehrhardt, Gary
    View/Open
    [PDF] DevelopmentPortableSourceProduction.pdf (14.25Kb)
    Date
    2005
    Contributor
    University of Missouri--Columbia. Office of Undergraduate Research
    Format
    Presentation
    Metadata
    [+] Show full item record
    Abstract
    Rhenium 188 is a radioisotope that is potentially useful for treatment of certain types of cancer including bone cancer and circulating tumors. Its short half-life of 16.7h however makes it an awkward choice for clinical use as much of the product will decay during shipping. This project focuses on the development of a portable source of producing high specific activity Rhenium188 from a longer lived (t1/2 = 69.4d), low specific activity source; Tungsten 188. Tungsten 188 is obtained by double neutron capture from Na2186WO4. Peroxide complexes of the Sodium Tungstate (Na2186WO4) and Zirconyl Nitrate (ZrO(NO3)2) are formed and then mixed with heating to yield a ZrO186WO4•XH2O gel precipitate. This is loaded into a column and washed with saline. As the W-188 decays to Re-188, high specific activity Sodium Perrehnate (Na188ReO4) will be eluted from the column. This can then be reduced to form the final drug on location. Future studies may include a similar method of production for a Mo-99/Tc-99m generator, another drug commonly used for imaging. The final poster will also discuss crystalline content of the ZrO186WO4•XH2O gel, which must be minimized to maximize the yield of Re-188.
    URI
    http://hdl.handle.net/10355/2179
    Part of
    2005 Summer Undergraduate Research and Creative Achievements Forum (MU)
    Collections
    • 2005 Summer Undergraduate Research and Creative Achievements Forum (MU)

    Send Feedback
    hosted by University of Missouri Library Systems
     

     


    Send Feedback
    hosted by University of Missouri Library Systems