Browsing School of Medicine (MU) by Thesis Advisor "Cook, James L."
Now showing items 1-6 of 6
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Biological responses of ligament and tendon graft-derived fibroblasts to clinical levels of cyclic strain
(University of Missouri--Columbia, 2020)Anterior Cruciate Ligament (ACL) is one of the major ligaments in the knee. ACL injury is the partial or complete tear of the ACL usually as a consequence of a traumatic sports related injury. ACL injury commonly affects ... -
Biomechanical and immunological contributions to osteochondral allograft transplantation outcomes
(University of Missouri--Columbia, 2023)Osteochondral allograft (OCA) transplantation offers a reliable option for treating complex articular injuries in multiple joints, but treatment failure rates remain a concern. Lack of functional integration of OCAs is a ... -
Development of translational models for intervertebral disc degeneration using a comparative approach for canine and human patients
(University of Missouri--Columbia, 2020)Intervertebral discs (IVDs) are unique musculoskeletal tissues within functional spinal unit organs comprising the spinal column that distribute loads and allow complex movements for vertebrates. IVD degeneration has been ... -
Pass the salt : elucidating the chondroprotective properties of hyperosmolar saline irrigation solutions
(University of Missouri--Columbia, 2023)[EMBARGOED UNTIL 12/1/2024] Arthroscopy is the most commonly performed orthopaedic surgery procedure. During arthroscopic surgery, a continuous flow of irrigation solution is necessary to distend the joint, remove debris, ... -
Pathobiological analysis of developmental dysplasia of the hip and its progression to osteoarthritis
(University of Missouri--Columbia, 2022)Developmental dysplasia of the hip (DDH) is recognized as one of the leading causes of early-onset hip osteoarthritis and a primary reason for undergoing total hip arthroplasty prior to 50 years of age. Even with an increase ... -
Patient adherence to orthopaedic treatment plans : toward patient-centered definitions, measurement, and management
(University of Missouri--Columbia, 2023)[EMBARGOED UNTIL 5/1/2024] Patient adherence to prescribed management protocols is associated with improved function, higher patient satisfaction, and lower complication rates following orthopaedic treatments. While adherence ...