School of Medicine (MU)
The University of Missouri School of Medicine has improved health, education and research in Missouri for more than 160 years. MU physicians treat patients from every county in the state, and MU is a primary provider of training for all physicians in Missouri. The School of Medicine's more than 650 faculty physicians and scientists educate approximately 1,000 medical students, residents, fellows and other students seeking advanced degrees. Their research is focused on potentially lifesaving discoveries that address the most prevalent health problems.
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The relationship between off-site inpatient gastroenterology consultations and timeliness of care delivery
(University of Missouri, Department of Medicine, Division of Hospital Medicine, 2023-06)Introduction: Gastroenterologists are increasingly responsible for providing inpatient care at multiple facilities. Here, we hypothesized that a single gastroenterology team covering two facilities impacts care delivery ... -
Shared decision making : a win-win situation for both patients and physicians
(University of Missouri, Department of Medicine, Division of Hospital Medicine, 2023-04)"Shared decision making (SDM) is a bidirectional, interactive approach that provides a structured pathway for physicians to collaborate with patients to arrive at healthcare decisions based on their goals, preferences, and ... -
Patient with persistent left superior vena cava presenting as acutely decompensating cardiac arrhythmia
(University of Missouri, Department of Medicine, Division of Hospital Medicine, 2023-04)A 75-year-old female presented to an outlying emergency room with dizziness, nausea and vomiting. She was noted to be in complete heart block and rapidly deteriorated clinically with pulseless ventricular tachycardia needing ... -
Social media : an opportunity for fidelity in extension of the traditional physician-patient relationship
(University of Missouri, Department of Medicine, Division of Hospital Medicine, 2023-01)Social media (SM) sites are a critical component of our modern society, increasingly present not only in our personal lives, but also in professional spheres.1 Within the medical profession, particularly during the ongoing ... -
Microbiological and electrophoretic studies of the binding of antibiotics by milk and milk components
(University of Missouri--Columbia, 1970)"The most common form of mastitis is associated with the growth and multiplication of bacteria in the milk secreting tissues of the udder. The infected gland reacts to microbial invasion and the host defense mechanism may ... -
Evolution, transmission, and clinical impacts of SARS-CoV-2 and influenza viruses
(University of Missouri--Columbia, 2023)[EMBARGOED UNTIL 12/1/2024] Influenza and coronaviruses are leading causes of human respiratory diseases, causing substantial global impact. The ongoing evolution of SARS-CoV-2 and influenza viruses continues to trigger ... -
Pass the salt : elucidating the chondroprotective properties of hyperosmolar saline irrigation solutions
(University of Missouri--Columbia, 2023)[EMBARGOED UNTIL 12/1/2024] Arthroscopy is the most commonly performed orthopaedic surgery procedure. During arthroscopic surgery, a continuous flow of irrigation solution is necessary to distend the joint, remove debris, ... -
Chronic vagotomy induces nTS glial activation, reduced glutamatergic signaling, and blunted cardiorespiratory responses
(University of Missouri--Columbia, 2023)The brainstem nucleus tractus solitarii (nTS) is the first site of integration of viscerosensory information provided by afferents of the vagus nerves. The nTS critically contributes to cardiorespiratory function and ... -
A role played by sex in innate immune memory and disease severity
(University of Missouri--Columbia, 2023)While immunological memory has traditionally been understood to be solely within the purview of adaptive immunity, recent evidence has shown that a type of "memory" exists in innate immune cells, as a prior insult can lead ... -
Interplay of Bacillus anthracis spore proteins in the assembly process of the exosporium
(University of Missouri--Columbia, 2023)Spores are the infectious form of the zoonotic pathogen, Bacillus anthracis. The outermost layer of these spores is the exosporium. It consists of a basal layer (major structural proteins are ExsY, CotY, BxpB, and ExsFB) ... -
Yeast mutants containing elevated methionine
(University of Missouri--Columbia, 1983)Yeasts are deficient in methionine which restricts the nutritive value of the protein. The objective of this research was to produce a methionine-rich mutant. Mutants of Candida tropical is ATCC 1369, Candida tropica!is ... -
Synergistic inactivation of Escherichia coli and phage T7 by near-ultraviolet radiation and hydrogen peroxide
(University of Missouri--Columbia, 1979)A non-1ethal concentration of H2O2 enhances NUV inactivation of Escherichia coli and its phages. Three distinct types of synergistic interaction were identified. Conditions were established which allowed the specific ... -
L-tryptophan photoproduct : effect on DNA replication and DNA repair in Escherichia coli
(University of Missouri--Columbia, 1974)"This study was stimulated by two important discoveries. The first of these came to a focus when it was observed that recombinationless (rec) mutants of bacteria were readily killed by near-UV irradiation. Recognition of ... -
The role of serum-glucocorticoid-regulated kinase (SGK1) in arterial reactivity
(University of Missouri--Columbia, 2023)[EMBARGOED UNTIL 8/1/2024] Objective: In the vascular system, aldosterone exerts several actions via genomic and non-genomic pathways through MR receptor-dependent/independent mechanisms. Aldosterone exerts its effect by ... -
Effects of hip joint orientation and skeletal torsion on human locomotor biomechanics and evolution
(University of Missouri--Columbia, 2023)[EMBARGOED UNTIL 8/1/2024] Bipedal locomotion is a defining feature of the human lineage. However, the form of bipedality in different hominin taxa and the timing of emergence of a human-like striding bipedal gait have ... -
Intervertebral disc degeneration : symptomatic and asymptomatic distinguishers
(University of Missouri--Columbia, 2023)Introduction: It is currently not possible to distinguish symptomatic (S) from asymptomatic (A) intervertebral disc degeneration (IVDD) based on patient factors or the degree of degeneration. Additionally, it is not known ... -
Should RAAS blockade therapy be continued in patients with advanced renal disease?
(Family Physicians Inquiries Network, 2023-04)Q: Should RAAS blockade therapy be continued in patients with advanced renal disease? Evidence-based answer: PROBABLY. Renin-angiotensinaldosterone system (RAAS) blockade therapy should be continued in most patients with ... -
Is there benefit to adding ezetimibe to a statin for the secondary prevention of CVD?
(Family Physicians Inquiries Network, 2023-06)Q: Is there benefit to adding ezetimibe to a statin for the secondary prevention of CVD? Evidence-based answer: YES. In patients with known cardiovascular disease (CVD), ezetimibe with a statin decreases major adverse ... -
Should antenatal testing be performed in patients with a pre-pregnancy BMI ≥ 35?
(Family Physicians Inquiries Network, 2023-03)Q: Should antenatal testing be performed in patients with a pre-pregnancy BMI ≥ 35? Evidence-based answer:Possibly. Elevated BMI is associated with an increased risk for stillbirth (strength of recommendation [SOR], B; ... -
Is low-dose naltrexone effective in chronic pain management?
(Family Physicians Inquiries Network, 2023-09)Q: Is low-dose naltrexone effective in chronic pain management? Evidence-based answer: YES. Low-dose naltrexone is as effective as amitriptyline in the treatment of painful diabetic neuropathy and has a superior safety ...