• Deletion of IP₃ receptor2 in astrocytes enhances the hippocampal neurogenesis in adult mice 

    Chang, Wenting (Biological engineer) (University of Missouri--Columbia, 2014)
    [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Neurogenesis (birth of neurons) is a process by which neurons are generated from neural progenitor cells. It mainly occurs in two regions of brain, one ...
  • The impact of neuronal Nampt on motor function of mice 

    Zhang, Qiao (University of Missouri--Columbia, 2016)
    [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Nicotinamide phosphoribosyltransferase (Nampt), also named visfatin and pre-B cell colony-enhancing factor (PBEF), is the rate-limiting enzyme converting ...
  • Regulation of calcium signaling by p130PH in astrocytes 

    Cui, Wenju, 1984- (University of Missouri--Columbia, 2009)
    Ca2+ signaling is a characteristic form of astrocyte excitability, but its role in ischemia is not clearly understood. Our previous study (Ding et al., 2009) demonstrated that astrocytes exhibit enhanced Ca2+ signaling ...
  • The role of astrocytic calcium signaling in brain damage after photothrombosis 

    Xie, Yicheng (University of Missouri--Columbia, 2011)
    [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Ischemic stroke is the third leading cause of death in industrialized countries. Our previous study found elevated [Ca[superscript 2+]]i signals in ...
  • The role of metabotropic glutamate receptor 5 in cerebral ischemia 

    Lin, Hsin-Yun (University of Missouri--Columbia, 2014)
    [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Group I metabotropic glutamate receptor 5 (mGluR5), belongs to G-protein coupled receptors family and plays important roles in CNS disorders including ...