Browsing Theses (MU) by Thesis Advisor "Stoker, Aaron M."
Now showing items 1-6 of 6
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Assessment of biomarker production by osteoarthritic osteochondral tissues and correlation to the biomechanical, biochemical, and histological properties
(University of Missouri--Columbia, 2016)Osteoarthritis (OA) is the most prevalent form of arthritis and is a significant cause of pain and disability worldwide. Treatment options available are only capable of controlling symptoms until progression to end-stage ... -
Characterization of the relationship between radiographic grading and biomarkers in patients with knee osteoarthritis
(University of Missouri--Columbia, 2020)"Osteoarthritis (OA) is a whole-joint degenerative disease, affecting more than 25% of the adult population. Currently, OA is most commonly diagnosed based on radiographic documentation. However, radiographic grading is ... -
Development of the human ex vivo split tissue osteoarthritis model
(University of Missouri--Columbia, 2017)Osteoarthritis (OA) is a disease characterized by loss of functional articular cartilage with associated whole-joint pathology and resultant pain and disability, which is projected to affect 59.4 million Americans by 2020. ... -
Intervertebral discs : metabolic responses to load, injury, and pro-inflammatory stimulation
(University of Missouri--Columbia, 2020)Introduction: Intervertebral disc (IVD) degeneration is a significant cause of back pain and disability. Factors such as trauma and magnitude and frequency of loading are associated with IVD degeneration. However, the ... -
Metabolic responses of meniscal tissue to collagenase stimulation
(University of Missouri--Columbia, 2019)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Meniscal degeneration as a result of injury or aging is a common contributing factor in the development of knee OA. Meniscal degeneration develops and ... -
Regional mapping of the osteoarthritic joint
(University of Missouri--Columbia, 2019)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Osteoarthritis (OA) progresses from a focal lesion of articular cartilage to whole-joint inflammation and degradation. The "focal spread" progresses ...