Sound duration selectivity in bat midbrain inferior colliculus

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Sound duration selectivity in bat midbrain inferior colliculus

Please use this identifier to cite or link to this item: http://hdl.handle.net/10355/4369

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dc.contributor.advisor Jen, Philip H.-S. en
dc.contributor.author Wu, Chung-Hsin, 1965- en_US
dc.date.accessioned 2010-01-12T17:05:54Z
dc.date.available 2010-01-12T17:05:54Z
dc.date.issued 2006 en_US
dc.date.submitted 2006 Fall en
dc.identifier.other WuC-121306-D6162 en_US
dc.identifier.uri http://hdl.handle.net/10355/4369
dc.description The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. en_US
dc.description Title from title screen of research.pdf file (viewed on August 9, 2007) en_US
dc.description Vita. en_US
dc.description Includes bibliographical references. en_US
dc.description Thesis (Ph. D.) University of Missouri-Columbia 2006. en_US
dc.description Dissertations, Academic -- University of Missouri--Columbia -- Neuroscience. en_US
dc.description.abstract Sound duration is an important acoustic parameter that contributes to the distinct spectral and temporal attributes of individual biological sounds and is therefore important for sound recognition in human speech, animal communication and bat echolocation. The main objective of this thesis is to examine the duration selectivity of neurons in the central nucleus of the midbrain inferior colliculus (IC) using bats as the mammalian model system under stimulation conditions of single pulses, temporally patterned pulse trains and pulse-echo (P-E) pairs. This thesis also studies the role of GABAergic inhibition in shaping the duration selectivity of IC neurons using iontophoretic application of GABA or bicuculline, which is an antagonist for GABAA receptors. The data obtained from these studies show the following. (1) Neurons at upper IC have sharper duration selectivity than neurons in the deeper IC. (2) GABAergic inhibition contributes to sharpening of duration selectivity of IC neurons to sound pulses in rapid sequences, pulse repetition rate (PRR) of pulse trains, and shortening of pulse duration and P-E gap. (3) The effect of bicuculline application on duration selectivity is more pronounced at high than at low PRR while the opposite is true during GABA application. en_US
dc.language.iso en_US en_US
dc.publisher University of Missouri--Columbia en_US
dc.relation.ispartof 2006 Freely available dissertations (MU) en_US
dc.subject.lcsh Mesencephalon en_US
dc.subject.lcsh Inferior colliculus en_US
dc.subject.lcsh Sound production by animals en_US
dc.subject.lcsh Bat sounds en_US
dc.subject.lcsh GABA -- Antagonists en_US
dc.title Sound duration selectivity in bat midbrain inferior colliculus en_US
dc.type Thesis en_US
thesis.degree.discipline Neuroscience en_US
thesis.degree.grantor University of Missouri--Columbia en_US
thesis.degree.name Ph. D. en_US
thesis.degree.level Doctoral en_US
dc.identifier.merlin .b59290316 en_US
dc.identifier.oclc 163585619 en_US
dc.relation.ispartofcommunity University of Missouri-Columbia. Graduate School. Theses and Dissertations. Dissertations. 2006 Dissertations


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