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dc.contributor.advisorFeng, Zaichuneng
dc.contributor.authorSeo, Duckbong, 1971-eng
dc.date.issued2007eng
dc.date.submitted2007 Summereng
dc.descriptionThe entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file.eng
dc.descriptionTitle from title screen of research.pdf file (viewed on December 13, 2007)eng
dc.descriptionVita.eng
dc.descriptionIncludes bibliographical references.eng
dc.descriptionThesis (Ph. D.) University of Missouri-Columbia 2007.eng
dc.descriptionDissertations, Academic -- University of Missouri--Columbia -- Mechanical and aerospace engineering.eng
dc.description.abstractThe objectives of this research are developing and improving an inexpensive and convenient microfluidic device to apply to sperm cell sorting. Based on well known soft-lithography fabrication method which contains rapid prototyping and wet-etching, the polymeric microfluidic devices, mainly microchannels, are fabricated. The fabrication processes of microfluidic devices are completed without an expensive cleanroom facility. To successfully design the microfluidic devices, we built mathematical flow models for single and multiple microchannels using fluid flow equations that govern the motion of the Newtonian liquid. These mathematical models are used to optimize the design of the microfluidic devices. The flows in the completed microfluidic system are observed using an inverted microscope and recorded by a digital camera. Experiments on fluid flow and on the movement of small particles including cells are conducted. These experiments lead to the development of a Motile sperm Sorting Microfludic System (MSMS).eng
dc.identifier.merlinb6152055xeng
dc.identifier.oclc183669954eng
dc.identifier.urihttps://hdl.handle.net/10355/4798
dc.identifier.urihttps://doi.org/10.32469/10355/4798eng
dc.languageEnglisheng
dc.publisherUniversity of Missouri--Columbiaeng
dc.relation.ispartofcollectionUniversity of Missouri--Columbia. Graduate School. Theses and Dissertationseng
dc.subject.lcshSpermatozoaeng
dc.subject.lcshFlow cytometryeng
dc.subject.lcshCell separationeng
dc.subject.lcshMicrofluidics -- Mathematical modelseng
dc.titleA development of the motile sperm sorting microfluidic deviceseng
dc.typeThesiseng
thesis.degree.disciplineMechanical and aerospace engineering (MU)eng
thesis.degree.grantorUniversity of Missouri--Columbiaeng
thesis.degree.levelDoctoraleng
thesis.degree.namePh. D.eng


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