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Targeting the guanylate cyclase c receptor with an agonist peptide from enterotoxegenic Y. Enterocolitica [abstract]
(2010-03)
Heat-stable enterotoxin peptides (ST's) are expressed by enterotoxigenic strains of bacteria in order to co-opt an endogenous ligand-receptor system that regulates fluid homeostasis within the gut. Bacteria such as E. coli, ...
The use of the Nintendo Wii for balance and cognition as a trement modality in occupational therapy in persons with multiple sclerosis for increased independence in activities of daily living [abstract]
(2010-03)
Objective: Examine the effectiveness of the Nintendo Wii on balance and cognition deficits to increase independence in activities of daily living for an individual with MS. Design: ABA single subject experimental design ...
Development of an in vitro model of quail vasculogenesis [abstract]
(2010-02)
Blood supply to virtually all tissues depends on endothelial cells, which form the linings of blood vessels. Growth and formation of endothelial cells occurs in two ways. Vasculogenesis describes the initial proliferation ...
Estrogen receptor and estrogen related receptor may corporatley regulate hypoxic gene expression [abstract]
(2010-03)
Tumor cells can undergo adaptation to the hypoxia environment created by rapid growth of tumor cells to persist growing. A main regulator of hypoxia induced gene expression is hypoxia-inducible factor (HIF), and HIF can ...
Identifying angiotensin II effects on protein kinase B activation in insulin metabolic signaling [abstract]
(2010-03)
Inappropriate activation of the Renin-Angiotensin-Aldosterone System has been linked to oxidative stress and insulin resistance. Whereas insulin binds to its receptor and triggers tyrosine phosphorylation of Insulin Receptor ...
Identification of the signaling networks involved in breast cancer metastasis to the brain using proteomic approaches [abstract]
(2010-03)
Brain is a common site of breast cancer metastasis, associated with significant neurologic morbidity, decreased quality of life, and greatly shortened survival. Development of new preventive and therapeutic strategies for ...
Evaluation of heart attack admissions pre- and post-implementation of a smoke-free indoor air policy [abstract]
(2010-03)
Multiple laboratory and epidemiological studies find secondhand smoke exposure causes adverse health outcomes. Additionally, an increasing number of studies at community, state and national levels identify significant ...
The effects of metformin therapy on BMI and biochemical markers among overweight children and adolescents [abstract]
(2010-03)
Introduction: In the United States, overweight adolescents are likely to continue to gain weight over time and are more likely to become overweight adults. High rates of child and adolescent obesity leave physicians searching ...
Establishment of cohort of consecutive ANCA test requests at MU- Preliminary 3 month data review [abstract]
(2010-03)
Background: Anti Neutrophil Cytoplasmic Antibodies (ANCA) are used to diagnose and monitor certain primary small vessel vasculitides. The results are often nonspecific. ANCA testing guidelines and gating policies have been ...
Effect of resistance training dose on metabloic responses and behavior habits [abstract]
(2010-03)
Purpose: To compare the acute dose responses of total body resistance training (RT, 1 set vs. 3 sets) on resting energy expenditure (REE), respiratory quotient (RQ), fasting blood free fatty acid (FFA), glucose (G), insulin ...
Managing changes of health information system by a conflict viewpoint [abstract]
(2010-03)
This research studies group conflicts within process of health information system (HIS) in terms of its development and implementation, aiming at managing changes through conflicts acquisition and representation with ...
Intermolecular complexes of MT1-MMP, Cdc42 and 2 1 EC lumen formation in 3D collagen matrices [abstract]
(2010-03)
A major focus of our laboratory is to elucidate molecular mechanisms controlling the ability of endothelial cells (ECs) to form luminal structures during vascular morphogenesis in 3D collagen matrices. EC luminal and tube ...
The impact of body mass index on achievement of functional changes during inpatient rehabilitation for lower limb amputees [abstract]
(2010-03)
Objective: This study examined the impact of Body Mass Index (BMI) on functional outcomes during inpatient rehabilitation for patients with amputations. Design: A retrospective chart review was conducted using a computerized ...
Improving patient care and provider efficiency with innovative tools within the electronic medical record [abstract]
(2010-03)
With residents and attending facing more limited work hours, the need for an efficient rounding system has become essential. An analysis of the initial EMR-generated rounding report found that residents and attendings ...
Integrin regulation of beta-catenin signaling in ovarian carcinoma [abstract]
(2010-03)
In 2006, there were 20,180 new cases of epithelial ovarian carcinoma and less than 30% of patients survive 5 years after developing distant metastases. Based on these statistics, the need for elucidation of the mechanisms ...
Improving physician efficiency and patient care : assessing an electronic mood disorder questionnaire [abstract]
(2010-03)
Bipolar disorder is a serious psychiatric illness characterized by periods of both depression and mania. Diagnosis of bipolar disorder is often missed in primary care settings as many patients are incorrectly diagnosed ...
Next generation tyrosine-mutant AAV8 shows high mouse corneal endothelial transduction in vivo [abstract]
(2010-03)
Purpose: Recently, point mutations in surface-exposed tyrosine residues have been shown to increase AAV transduction significantly. We examined the efficacy of conventional AAV8 and next generation tyrosine-mutant AAV8 ...
Novel 3D analysis of the proximal femur and hip joint function in arhropoids : implications for the human hip joint functional analyses [abstract]
(2010-03)
Fossil catarrhines are hypothesized to display a range of locomotor adaptations, creating specialized joint morphology. Many of these primate taxa are known from the proximal femur, which directly reflects hip function. ...
Patients with venous tromboembolism have higher prevalence of obstructive sleep apnea [abstract]
(2010-03)
Background: Obstructive sleep apnea (OSA) has been linked to many cardiovascular diseases. Recent studies have linked OSA, endothelial dysfunction, and elevated CRP. The link between OSA and venous thromboembolic events ...
Novel method for analyzing femur geometry variation [abstract]
(2010-03)
Designing effective orthopaedic implants requires detailed knowledge of variation in human bone form. Incomplete characterization of this variation can result in implants - such as femoral intramedullary nails - that may ...