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FAST kinase domain-containing protein 1 in mitochondrial function, cell death and cardiovascular disease /
(University of Missouri--Columbia, 2016)
Cell death occurs during myriad circumstances and varied physiological and pathological conditions. Identifying novel modulators of cell death pathways is crucial to understanding and controlling cell death. Therefore, we ...
Essays in corporate finance /
(University of Missouri--Columbia, 2016)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] [1] NEW CLASSIFICATIONS FOR CHAIRMEN OF THE BOARD -- I DID IT MY WAY. In this paper I determine whether a new classification of chairmen (former CEOs) ...
Studies on contagious abortion
(University of Missouri--Columbia, 1918)
Text from Introduction: "This thesis includes a review of the more important literature relating to contagious abortion or infectious abortion that was available, and particularly that dealing with experimental researches ...
The effect of sodium/hydrogen exchanger inhibition on chemotherapy-induced intestinal epithelial damage
(University of Missouri--Columbia, 2017)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The small intestinal epithelium is one of the most rapidly dividing tissues in the mammalian body, making it an inadvertent target of non-specific ...
A novel approach to the clinical diagnosis and treatment of canine histiocytic sarcoma
(University of Missouri--Columbia, 2017)
This work provides a review of canine histiocytic sarcoma (HS) including background immunology, diagnosis, treatment, and prognosis. Given the poor prognosis of HS compared to other soft tissue sarcomas in dogs, the research ...
Cholesterol synthesis inhibitors prevent growth and metastasis of breast cancer cells
(University of Missouri--Columbia, 2017)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Clinical trials and studies show that post-menopausal women undergoing hormone replacement therapy containing a combination of estrogen and progestin ...
Role of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase in upregulation of intermediate-conductance Ca[superscript 2+] -activated K[superscript +] channels (K[subscript Ca]3.1) associated with atherosclerosis
(University of Missouri--Columbia, 2010)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] A key risk factor for the development of atherosclerosis is familial hypercholesterolemia (FH), a genetic disease characterized by elevated levels of ...
The role of CFTR in regulating the cell cycle of intestinal stem cells
(University of Missouri--Columbia, 2016)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] [Abstract taken from public pdf.] Cystic fibrosis (CF) patients and CF mouse models have an increased risk for gastrointestinal (GI) cancer. Intestinal ...
Examination of nucleus accumbens mechanisms underlying the motivation for physical activity
(University of Missouri--Columbia, 2017)
Physical inactivity, a primary contributor to numerous diseases including obesity, type 2 diabetes, depression, and dementia, has reached pandemic levels worldwide. Alarmingly, the percentage of individuals engaging in ...
The use of magnetic resonance imaging and proton spectroscopy to identify critical tissues in dogs with Duchenne Muscular Dystrophy for future assessment of therapeutic intervention : a pilot study
(University of Missouri--Columbia, 2018)
Duchenne's Muscular Dystrophy is a debilitating disease that affects skeletal and cardiac muscle of 1 in 5000 male births. In the last thirty years, the gene responsible for the encoding of Dystrophin has been identified, ...
Effect of induced hindlimb length difference on bodymounted inertial sensor measures of hindlimb lameness in horses
(University of Missouri--Columbia, 2019)
This study has investigated the effect of induced hindlimb length difference on differences in minimum and maximum pelvic heights in horses trotting in a straight line and lungeing on both hard and soft surfaces. The horses ...
The cystic fibrosis transmembrane conductance regulator and acid-base transporters of the murine duodenum
(University of Missouri--Columbia, 2006)
The alkaline mucus barrier of the duodenum plays an important role in protecting the epithelium from acidic chyme entering from the stomach. Active HCO₃⁻ secretion involves the apical membrane activities of the cystic ...
Sensory integration during blood loss in conscious rabbits
(University of Missouri--Columbia, 2006)
Central nervous system integration of sensory inputs is critical for orchestrating physiological responses to stress. The focus of my doctoral research was investigating the physiological consequences of sensory stimulation ...
In vitro evaluation of veterinary and human suture anchors in metaphyseal bone of the canine tibia
(University of Missouri--Columbia, 2006)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Suture anchors, also called bone or tissue anchors, provide orthopedic surgeons a mechanism for secure fixation of soft tissues to bone. A human system ...
Characterization of the humoral immune response to a commercial staphylococcus aureus mastitis vaccine
(University of Missouri--Columbia, 2006)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The objective of this thesis was to test the hypothesis that a commercial vaccine for bovine S. aureus mastitis fails to induce a humoral immune response ...
Role of the intermediate-conductance Ca²⁺-activated K⁺ channel (K[ca]3.1) in coronary smooth muscle cell phenotypic modulation
(University of Missouri--Columbia, 2007)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Smooth muscle cell phenotypic modulation is characterized by suppression of smooth muscle specific marker gene expression, migration, and proliferation ...
Fgf2-stimulated proliferation is lower in muscle precursor cells from old rats
(University of Missouri--Columbia, 2009)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] In aged skeletal muscle, impairments in the regrowth and regeneration may be explained by a decreased responsiveness of muscle precursor cells (MPCs), ...
Estradiol regulates multiple tetrodotoxin-sensitive sodium currents in gonadotropin releasing hormone neurons: implications for cellular regulation of reproduction
(University of Missouri--Columbia, 2009)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The gonadotropin releasing hormone (GnRH) neuron is the pivotal control center in a tightly regulated reproductive axis. Estradiol typically has a ...
Sympathetic control of the collateral circulation : effects of time post-occlusion and exercise training
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] These studies evaluated the role of alpha-adrenergic receptors ([alpha]AR) and NPYergic receptors in the collateral circulation following acute and ...
Post-angioplasty restenosis : the effects of exercise training
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Percutaneous transluminal coronary angioplasty (PTCA) stimulates vascular cell proliferation and migration resulting in restenosis of the revascularized ...