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Gene therapy in spinal muscular atrophy : RNA-based strategies to modulate the pre-mRNA splicing of survival motor neuron
(University of Missouri--Columbia, 2008)
Gene expression is the required process in eukaryotes in which DNA is transcribed into pre-mRNA, spliced to produce "mature" mRNA and translated into proteins. Inaccuracies in splicing events are receiving more attention ...
Metamorphism of the Wales Group and Moira Group on Prince of Wales and Dall Islands, southeastern Alaska
(University of Missouri--Columbia, 2007)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] This study examines the metamorphic history of the Proterozoic to Early Ordovician Wales Group and the newly-named Ordovician to Silurian Moira Group ...
Gene expression profiling of bovine ovarian follicular selection
(University of Missouri--Columbia, 2006)
Lack of, or abnormal, ovarian follicular development is a major factor associated with impaired fertility in mammals. However, development of new treatments is limited by our poor understanding of ovarian follicular ...
Analysis and modeling of direct selective laser sintering of two-component metal powders
(University of Missouri--Columbia, 2005)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Direct Selective Laser Sintering (SLS) is an emerging technology of Solid Freeform Fabrication (SFF) that 3-D parts are built from the metal-based ...
Examination of metabolic and regulatory networks of desulfovibrio species
(University of Missouri--Columbia, 2004)
The sulfate-reducing bacteria are a morphologically diverse group of organisms characterized by the ability to couple the enzymatic reduction of sulfate to energy production and growth. This metabolic activity has profound ...
Who drives defense policy : elites or public interest?
(University of Missouri--Columbia, 2011)
With a massive budget deficit and an ever-increasing national debt, while Congress and the President almost shut down the federal government over funding for Planned Parenthood in 2011, defense spending seems to be nearly ...
Molecular cloning and characterization of regulatory enzymes in threonine biosynthetic pathway from soybean
(University of Missouri--Columbia, 2007)
Soybeans (Glycine max [L.] Merr.) are a good source of protein and oil. Despite being a very good source of protein, soybeans nutritional value is limited by low proportion of sulfur amino acids methionine and cysteine ...
Fluorescence spectroscopy and parallel factor analysis of waters from municipal waste sources
(University of Missouri--Columbia, 2007)
location. Parallel Factor Analysis (PARAFAC) has recently been used to effectively model EEM data sets. This thesis continues the study of the EEM/PARAFAC technique by applying it to waters of municipal waste sources. Bi-weekly samples were collected over a...
The effects of axotomy on the biophysical properties of reticulospinal neurons in larval lamprey
(University of Missouri--Columbia, 2006)
Following severe spinal cord injury (SCI), in adult higher vertebrates there is little or no axonal regeneration, and animals remain paralyzed below the lesion. In contrast, lower vertebrates such as the lamprey, following ...
Statistical analysis of multivariate interval-censored failure time data
(University of Missouri--Columbia, 2007)
A voluminous literature on right-censored failure time data has been developed in the past 30 years. Due to advances in biomedical research, interval censoring has become increasingly common in medical follow-up studies. ...
Effects of instructor-led feedback conferences on the level of reflective thought among senior-level students enrolled in a teaching methods course in agricultural education
(University of Missouri--Columbia, 2010)
The purpose of this experimental study was to describe the reflective thinking level of students both overall and by characteristics as well as to compare the effect of reflective feedback conference on students' reflective ...
Prospective radiolabled bombesin conjugates for prostate cancer imaging and therapeutic agents
(University of Missouri--Columbia, 2009)
-99m ([superscript 99][superscript-m]Tc), Copper-64 ([superscript 64 ]Cu) or Bismuth-213 ([superscript 213]Bi)....
Bayesian spatial data analysis with application to the Missouri Ozark forest ecosystem project
(University of Missouri--Columbia, 2006)
The first part studies the problem of estimating the covariance matrix in a star-shaped model with missing data. By introducing a class of priors based on a type of Cholesky decomposition of the precision matrix, we then ...
Understanding students' technology appropriation and learning perceptions in online learning environments
(University of Missouri--Columbia, 2005)
Distance education has the unique characteristic of using technologies as the primary means of delivery of instruction and interaction. The present study contributes to research dedicated to explaining or predicting phenomena ...
Communicating medical advances in television health news : the influence of a human interest frame on audiences' cognitive and emotional responses
(University of Missouri--Columbia, 2010)
The dissemination of scientific advances in medicine became popular in television health news over the last few decades. The purpose of this study is to investigate the influence of news frames in television health news ...
Effects of high fat loading on substrate utilization and performance during intermittent exercise in trained athletes
(University of Missouri--Columbia, 2008)
High intensity intermittent exercise is the most common form of exercise in competitive sport yet dietary factors that affect an athlete's performance in this capacity are rarely investigated. The purpose of this investigation ...
Modeling and optimization of the Mannheimia haemolytica vaccine production process
(University of Missouri--Columbia, 2017)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Leukotoxin (Lkt) from Mannheimia haemolytica has been discovered as the primary pathogenic factor for bovine respiratory disease (BRD), causing huge ...
Development of tailored preform processing technology for net-shape manufacturing of large monolithic structures
(University of Missouri--Columbia, 2007)
The aim of the present research effort involves exploration of a new processing approach, "Tailored Preform Processing (TPP)" technology for net-shape manufacturing of monolithic structures for the transportation industry. ...
Enhancing methanol electro-oxidation by double oxide incorporation with platinum on carbon nanotubes
(University of Missouri--Columbia, 2016)
Electro-oxidation of methanol was investigated on platinum catalyst supported on a double oxide nanocomposite support of tin oxide and carbon-doped titanium dioxide. The Pt-SnO2-C-/CNTs electro catalyst demonstrated about ...
Spatial distribution and historical dynamics of threatened conifers of the Dalat Plateau, Vietnam
(University of Missouri--Columbia, 2011)
The Dalat Plateau is one of several biodiversity hotspots in Vietnam. It is considered to be one of five centers of plant diversity and one of three endemic bird areas in the country. Almost half of the conifer species ...