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Selection of non-regular fractional factorial designs when some two-factor interactions are important
(2008)
Introduction: Non-regular two-level fractional factorial designs, such as Placket-Burman designs, are becoming popular choices in many areas of scientific investigation due to their run size economy and flexibility. The ...
Isolation and characterization of a baculovirus associated with the insect parasitoid wasp, Cotesia marginiventris, or its host, Trichoplusia ni
(University of Wisconsin, 2008)
A multiple nucleopolyhedrovirus (MNPV) was isolated from Trichoplusia ni (Hübner) (Lepidoptera: Noctuidae) larvae that had been stung by the parasitoid Cotesia marginiventris (Cresson) (Hymenoptera: Braconidae). The wild ...
Mineralocorticoid receptor antagonism attenuates vascular apoptosis and injury via rescuing protein kinase B activation
(American Heart Association, 2008)
Emerging evidence indicates that mineralocorticoid receptor (MR) blockade reduces the risk of cardiovascular events beyond those predicted by its blood pressure-lowering actions; however, the underlying mechanisms remain ...
Does case management improve diabetes outcomes?
(Family Physicians Inquiries Network, 2008)
Patients with type 2 diabetes benefit from case management, as evidenced by decreased glycated hemoglobin (HbA1c). The improvement in HbA1c appeared larger when case managers could make changes in medications independently ...
Leukotriene Receptor Antagonists for the Treatment of Allergic Skin Disorders
(Family Physicians Inquiries Network, 2008)
Evidence from small trials suggests that leukotriene receptor antagonists may have short-term effectiveness in reducing sleep disturbance and the observed intensity of atopic dermatitis in adults and children. (Strength ...
Differential Diagnosis of Tremor
(Family Physicians Inquiries Network, 2008)
The most common tremor in primary care is an exaggerated physiologic tremor, followed by essential tremor and tremors caused by Parkinson's disease. (Strength of Recommendation [SOR]: C, based on extrapolation from a ...
Does screening reduce lung cancer mortality?
(Family Physicians Inquiries Network, 2008)
Neither routine chest x-ray (with or without sputum cytology) nor low-dose computed tomography (CT) have been proven to reduce mortality when used for lung cancer screening, although low-dose CT screening does identify ...
Does birth weight predict childhood obesity?
(Family Physicians Inquiries Network, 2008)
A birth weight greater than 4,000 g is associated with an increased risk of obesity in both childhood and adolescence (strength of recommendation [SOR]: B, systematic review and multiple cohort studies).
Does antepartum perineal massage reduce intrapartum lacerations?
(Family Physicians Inquiries Network, 2008)
Yes--to a point. Antepartum perineal massage reduces both the incidence of perineal trauma requiring suturing and the likelihood of episiotomy in women who have never given birth vaginally. It reduces the incidence of ...
Effect of Antiepileptic Drugs on Oral Contraceptives
(Family Physicians Inquiries Network, 2008)
We found no studies that measure, or even estimate, any increase in pregnancy rates in women taking antiepileptic drugs. Antiepileptic drugs known to induce the hepatic cytochrome P450 (CYP450) isoenzyme cause decreased ...
Do any folk remedies or herbals help induce labor?
(Family Physicians Inquiries Network, 2008)
Breast stimulation and electroacupuncture help, while other common remedies that have been studied are ineffective, possibly unsafe, or both. Unilateral breast stimulation shortens the time until the onset of labor in women ...
Quality of Life in Older Persons with Dementia Living in Nursing Homes
(Family Physicians Inquiries Network, 2008)
There is no "gold standard" to measure the QOL in older persons with dementia. For those requiring increased care, nursing homes may offer some benefit, including more frequent physician assessment and treatment of pain ...
Should you treat carriers of pharyngeal group A strep?
(Family Physicians Inquiries Network, 2008)
The jury is out as to whether you should treat asymptomatic carriers of group A streptococci (GAS), because no studies specifically address the issue. In addition, many patients are unlikely to care about their carrier ...