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Best Alternatives to Statins for Treating Hyperlipidemia
(Family Physicians Inquiries Network, 2007)
but not total mortality. (SOR: A, based on review of RCTs). The effects of ezetimibe (Zetia) on cardiovascular outcomes and mortality are unknown. (SOR: C, based on a single RCT with disease-oriented evidence). Omega-3 fatty acid supplementation does not clearly...
Whom should you test for secondary causes of hypertension?
(Family Physicians Inquiries Network, 2014)
Evidence-based answer: It's recommended that all children and adolescents with a new diagnosis of hypertension undergo renal ultrasound and laboratory evaluation for renal pathology (strength of recommendation [SOR]: C, consensus-based guidelines...
Time to conception after miscarriage : how long to wait?
(Family Physicians Inquiries Network, 2019)
Q: Time to conception after miscarriage: how long to wait? Evidence-based answer: an interpregnancy interval (IPI) of < 6 months following miscarriage is associated with an increased live birth rate in subsequent pregnancy, lower risks of preterm...
Does injection of steroids and lidocaine in the shoulder relieve bursitis?
(Family Physicians Inquiries Network, 2004)
Subacromial steroid injection may provide a small, short-term benefit compared with placebo. The short-term effectiveness of steroid injection compared with nonsteroidal anti-inflammatory agents (NSAIDs) remains unclear. ...
Antidepressant Use During Pregnancy
(Family Physicians Inquiries Network, 2011)
the risk of congenital malformations or miscarriage. (Strength of Recommendation [SOR]: B, based on limited-quality, patient-oriented evidence.) The use of SSRIs or TCAs during pregnancy may increase the risk of preterm birth, low birth weight, respiratory...
Do patients with type 2 diabetes who aren't taking insulin benefit from self-monitoring blood glucose?
(Family Physicians Inquiries Network, 2013)
Patients with type 2 diabetes who aren't on insulin and perform self-monitoring of blood glucose (SMBG) show small but significant reductions in hemoglobin A1c (HbA1c) at 6 months but not at 12 months (strength of recommendation [SOR]: B, systematic...
How effectively do ACE inhibitors and ARBs prevent migraines?
(Family Physicians Inquiries Network, 2018)
Q: How effectively do ACE inhibitors and ARBs prevent migraines? Evidence-based answer: The angiotensin-converting enzyme (ACE) inhibitor lisinopril reduces the number of migraines by about 1.5 per month in patients experiencing 2 to 6 migraines...
What predicts a successful smoking cessation attempt?
(Family Physicians Inquiries Network, 2006)
Quit date abstinence (strength of recommendation [SOR]: B, based on low-quality randomized controlled trial [RCT] of healthy subjects) and refraining from tobacco products within the first 2 weeks after an attempt (SOR: A, based on 2 RCTs) predict...
Do cinnamon supplements improve glycemic control in adults with T2DM?
(Family Physicians Inquiries Network, 2020)
Q: Do cinnamon supplements improve glycemic control in adults with T2DM? Evidence-based answer: the answer isn't clear. Cinnamon supplements for adults with type 2 diabetes haven't been shown to decrease hemoglobin A1C (strength of recommendation...
Can mobile technology improve weight loss in overweight and obese patients?
(Family Physicians Inquiries Network, 2017)
Q: Can mobile technology improve weight loss in overweight and obese patients? Evidence-based answer: Yes, this technology can help in the short term. Mobile technology compared with minimal or no intervention increases short-term (<6 months) weight...
What is the best way to diagnose menopause?
(Family Physicians Inquiries Network, 2005)
No single test for menopause is highly sensitive and specific. The best predictors that a woman will enter menopause within 4 years include age at least 50 years, amenorrhea for 3 to 11 months, and menstrual cycle irregularity within 12 months...
What is a reasonable initial approach to the patient with fatigue?
(Family Physicians Inquiries Network, 2001)
with sedimentation rate, blood count, and glycohemoglobin and thyroid stimulating hormone (TSH) levels, particularly in older patients. Grade of Recommendation: C, based on case series and expert opinion...
Toxic Stress Education for Pediatric Practitioners to Improve Health Outcomes
(University of Missouri--Kansas City, 2018)
Toxic stress associated with adverse childhood experiences during childhood can have
catastrophic lifelong neurobiological, social, and emotional effects and has been shown to
decrease life expectancy up to 20 years. ...
Which detoxification regimens are effective for alcohol withdrawal syndrome?
(Family Physicians Inquiries Network, 2021)
Q: Which detoxification regimens are effective for alcohol withdrawal syndrom? Evidence based answer: Benzodiazepines remain the first-line regimen for alcohol withdrawal syndrome (AWS) and are the only class more effective than placebo for reducing...
Which complementary therapies can help patients with PMS?
(Family Physicians Inquiries Network, 2009)
doses of pyridoxine can cause neuropathy (SOR: B, RCT and meta-analysis of lower-quality studies). Insufficient evidence exists to recommend magnesium. St. John's wort and evening primrose oil aren't effective for managing PMS (SOR: B, inconsistent...
Implementation of a low-cost, web-based, multi-component training for trauma-focused cognitive-behavioral therapy
(University of Missouri--Columbia, 2018)
knowledge, use, and fidelity in TF-CBT. A multiple regression showed that previous TF-BT training, clinician attitudes towards evidence-based practices, and clinician age predicted training completion. Implications for web-based trainings and implementation...
How does pentoxifylline affect survival of patients with alcoholic hepatitis?
(Family Physicians Inquiries Network, 2008)
Pentoxifylline improves short-term survival in patients admitted to the hospital with severe alcoholic hepatitis (strength of recommendation [SOR]: B, a single published randomized controlled trial [RCT]). Pentoxifylline ...
Does acyclovir help herpes simplex virus cold sores if treatment is delayed?
(Family Physicians Inquiries Network, 2004)
When herpes simplex virus (HSV) type 1 lesions are in the papule or vesicle stage, there is no benefit to starting oral acyclovir (strength of recommendation [SOR]: C, based on expert opinion). However, topical acyclovir 5% cream applied 5 times a...
Does moderate exercise prevent MI for patients with coronary heart disease?
(Family Physicians Inquiries Network, 2004)
Moderate exercise reduces mortality for patients with known coronary heart disease but does not significantly decrease the risk of recurrent nonfatal myocardial infarction (MI) (strength of recommendation [SOR]: A, based on systematic review...
Evidence-based practice self-efficacy of speech-language pathologists across settings
(University of Missouri--Columbia, 2020)
if differences existed in each of four experience groups. Self-efficacy ratings were also compared based on degree held, area of practice, and years of experience. Participants (n = 342) completed a survey containing 10 demographic questions, 11 items from...