Validation of X-Ray Fluorescence-Measured Swine Femur Lead Against Atomic Absorption Spectrometry

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Validation of X-Ray Fluorescence-Measured Swine Femur Lead Against Atomic Absorption Spectrometry

Please use this identifier to cite or link to this item: http://hdl.handle.net/10355/10091

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dc.contributor.author Todd, Andrew C.
dc.contributor.author Moshier, Erin L.
dc.contributor.author Carroll, Spencer
dc.contributor.author Casteel, Stan W.
dc.date.accessioned 2011-03-02T15:41:28Z
dc.date.available 2011-03-02T15:41:28Z
dc.date.issued 2001-11
dc.identifier.citation Todd AC, Moshier EL, Carroll S, Casteel SW, 2001 Validation of X-Ray Fluorescence-Measured Swine Femur Lead Against Atomic Absorption Spectrometry. Environmental Health Perspectives 109(11) en_US
dc.identifier.uri http://hdl.handle.net/10355/10091
dc.description Reproduced with permission from Environmental Health Perspectives. DOI:10.1289/ehp.011091115 en_US
dc.description.abstract The aim of this study was to apply the technique of 109Cd-based K-shell X-ray fluorescence (XRF) bone lead measurements to swine femurs and to validate the concentrations obtained therefrom against an independent chemical measurement of bone lead: atomic absorption spectrometry (AAS). The femurs ranged in lead concentration from 1.0 to 24.5 µg of lead per gram of ashed bone, as measured by AAS. On average, XRF overestimated AAS-measured femur lead by 2.6 µg/g [95% confidence interval (CI), 1.1-4.0 µg/g], approximately 2 µg/g poorer than that observed in studies of human tibiae. Measurements of swine femur and, by extension, of nonhuman bones may require adjustment of the XRF spectrum peak extraction method. en_US
dc.description.sponsorship This study was supported by grants ES05697, ES06616, and ES07198 from the National Institute of Environmental Health Sciences, National Institutes of Health of the U.S. Public Health Services Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the NIEHS or NIH.
dc.language.iso en_US en_US
dc.publisher National Institute of Environmental Health Sciences en_US
dc.relation.ispartof Veterinary Pathobiology publications (MU) en_US
dc.subject.lcsh Atomic absorption spectroscopy en_US
dc.subject.lcsh X-ray spectroscopy en_US
dc.subject.lcsh Lead poisoning -- Animal models en_US
dc.title Validation of X-Ray Fluorescence-Measured Swine Femur Lead Against Atomic Absorption Spectrometry en_US
dc.type Article en_US
dc.source.harvested Environmental Health Perspectives Web site en_US
dc.relation.ispartofcommunity University of Missouri-Columbia. College of Veterinary Medicine. Department of Veterinary Pathobiology


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