Browsing Theses and Dissertations (MU) by Thesis Advisor "Middleton, John R."
Now showing items 1-6 of 6
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Advancements in the understanding of staphylococcal mastitis through the use of molecular tools
(University of Missouri--Columbia, 2017)The objectives of this work were: 1) to complete a whole genome sequence of a Staphylococcus chromogenes isolate that is known to persist in the mammary gland of a cow, 2) to define a genetic target that could easily and ... -
Characterization of the humoral immune response to a commercial staphylococcus aureus mastitis vaccine
(University of Missouri--Columbia, 2006)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The objective of this thesis was to test the hypothesis that a commercial vaccine for bovine S. aureus mastitis fails to induce a humoral immune response ... -
Epidemiology of non-aureus staphylococcal mastitis in dairy goats
(University of Missouri--Columbia, 2018)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The hypothesis of this work was that molecular-based speciation and strain-typing methods would help differentiate staphylococcal species with greater ... -
Fetoscopic in utero tracheal occlusion as a method to reduce fetal lung hypoplasia in a sheep model of congenital diaphragmatic hernia
(University of Missouri--Columbia, 2023)[EMBARGOED UNTIL 5/1/2024] Congenital diaphragmatic hernia (DH) is a potentially fatal malformation that occurs in 1/2500 human births. Pulmonary hypoplasia decreases survival rate due to compression of thoracic contents ... -
Intramammary infections in lactating Jersey cows: prevalence of pathogens and association of pathogen type with milk somatic cell count and persistence of infection
(University of Missouri--Columbia, 2022)There is limited data available regarding pathogens causing intramammary infections (IMI) in Jersey cows. The objectives of this study were to characterize the prevalence of IMI caused by different microorganisms in lactating ... -
The use of a lysostaphin fusion protein as a dry-cow treatment for chronic Staphylococcus aureua mastitis in dairy cattle
(University of Missouri--Columbia, 2013)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] This study evaluated the efficacy of a lysostaphin-fusion protein (Lyso-PTD) as a dry-cow therapy for the treatment of experimentally-induced chronic, ...