Search
Now showing items 41-58 of 58
Amphetamine Alters Group I mGluR Expression in the Rat Striatum and Medial Prefrontal Cortex
(2010-03)
Introduction: Group I metabotropic glutamate receptors (mGluR1/mGluR5 subtypes) and their key scaffolding protein Homer1b/c are densely expressed in the striatum. These receptors are believed to play important roles in ...
Effects of Isoflurane on Plasma-Membrane Calcium ATPase
(2010-03)
Introduction: Plasma membrane Ca2+-ATPase (PMCA) is a transmembrane enzymatic protein present in human neurons, myocytes, and RBCs which plays a role in controlling cellular Ca2+ levels by regulating intracellular ATP. ...
Toxicty of a Serotonin-derived Neuromelanin
(2010)
Introduction: POCD (Postoperative Cognitive Dysfunction) is associated with increased mortality and disability and may develop as a consequence of lipid peroxidative byproducts (i.e. acrolein), which accumulate with aging. ...
Porcine induced pluripotent stem cells (piPSC) for expanding the use of swine in biomedical research
(2010-03)
Our goal is to create porcine pluripotent stem cells, i.e. ones capable of differentiating into all cell types of the body that can expand the use of swine as a biomedical model for studying human disease. It is well ...
Development of a Telemetry Unit for Wireless Monitoring of Bone Strain
(2010-03)
A telemetry unit designed to monitor strain in bones is presented. This unit allows studying the relationship between bone load and bone mass in scenarios that were not possible with current setup. The current measuring ...
Public-Private Collaborations to Promote Adult Literacy
(2010-03)
Health literacy entered health care discourse when the 2003 National Adult Literacy Survey revealed that nearly half the US adult population has serious deficiencies in reading & computational skills, with one in four ...
Why Humans Do What They Do: Interdisciplinary Research on Realistic Decision Making
(2010)
MU has enormous potential to be the site of path-breaking interdisciplinary research on the topic of realistic decision making. Not only is this research a basic component of human life science, it also has clear application ...
Multi-disciplinary Collaborations in Measurement of Human Motion
(2010-03)
Bioengineering is a broad and rapidly-growing discipline defined as the application of engineering principles to biological systems. Although bioengineering is diverse in nature, the study of human movement is common to ...
Clinical and Computational Collaboration in Orthopaedic Biomechanics
(2010)
The mission of the Comparative Orthopaedic Laboratory at the University of Missouri-Columbia (COL-UMC) is three-fold: 1.To design and conduct the highest quality hypothesis-driven research focused on orthopaedic disorders ...
Motion Tracking for Smart Home Care
(2010-03)
Human body motion capture has a wide range of applications and is being extensively investigated. Areas of application include virtual and augmented reality, biomechanics, sign language translation, gait analysis and ...
An Intelligent Online System for Enhanced Recruitment of Patients for Clinical Research
(2010-03)
The recruitment and retention of subjects for clinical research has been identified as one of the bottlenecks in the development of new drugs and treatments by the healthcare industry. The Kansas City Area Life Sciences ...
Effect of Radius on Load Distribution within Mouse Forearm Structure: Experimental and Numerical Analyses
(2010-03)
It has been hypothesized that osteocytes are stimulated by local strain distribution within the bone subjected to mechanical loadings. This collaborative research project between bone biologists and mechanical engineers ...
Shelter Dog Behavior Improvement: Dog Walking as Enrichment
(2010)
Background: Several million dogs are euthanized in animal shelters annually after multiple relinquishment reasons (Scarlett, 2002; Salman, 1998; New, 2000 & Kass, 2001). Gains in pet adoptions are happening via shelter ...
A genetic linkage map of the fungus Phycomyces blakesleeanus
(2010-03)
Phycomyces blakesleeanus is a filamentous fungus of research interest because of its ability to sense and respond to its environment. The unicellular sporangiophores show growth responses to light, gravity, wind, chemicals ...
Guided-mode resonance biochip system for early detection of ovarian cancer
(2010-03)
A high-accuracy, sensor system has been developed that provides near-instantaneous detection of biomarker proteins as indicators of ovarian serous papillary carcinoma. Based upon photonic guided-mode resonance technology, ...
Tao3 mediates a phenotypic switch between amoeba-adapted and mammalian-adapted forms of Cryptococcus neoformans
(2010-03)
Many microbes are capable of changing phenotypes more frequently than due to basal mutation rates alone, and this ability is coupled to pathogenesis. The human pathogenic yeast Cryptococcus neoformans is found in the ...
Targeting Tick Borne Diseases
(2010)
Ticks transmit the majority of vector-borne diseases of human beings in the USA and of domestic animals worldwide. Among these, tick-borne rickettsial pathogens cause at least four important tick-borne zoonoses in the USA, ...
The Vision Research Center of Kansas City
(2010-03)
The Vision Research Center was founded as and is a well established collaboration of several of UMKC schools and Kansas City Medical Centers and thus offers an unprecedented interdisciplinary synergy with a unified goal: ...