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A novel PCR based DNA microanalyzer system for detection of viral genome
(University of Missouri--Columbia, 2006)
A micro-fluidic assay to quickly analyze microscopic samples of DNA is being developed for field applications. It consists of a micro-PCR chamber, micropumps, and micro-heaters. Additional components of the device include ...
Development of a FRET biosensor to detect the pathogen mycoplasma capricolum
(University of Missouri--Columbia, 2005)
Mycoplasmas are a species of bacteria that invade any type of cell and are adaptable to changing environments. We are developing an optical biosensor based on Fluorescence Resonance Energy Transfer (FRET) for detection of ...
Automatic four-limb IMU gait analysis in the canine DMD model
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Gait analysis is valuable for studying neuromuscular and skeletal diseases. Wearable motion sensors or inertial measurement units (IMUs) possess ...
Use of geographic information systems and remote sensing as automated tool for variable rate irrigation prescriptions
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Economic as well as water shortage pressure on agricultural use of water has placed added emphasis on efficient irrigation management. Center pivot ...
Multi-scale self-assembly of nanoenergetic materials utilizing functionalized graphene
(University of Missouri--Columbia, 2020)
The work described here-in focuses on the synthesis and characterization of novel nanoenergetic materials and is driven by overcoming the disadvantages of traditional nanoenergetic composites, improving the energetic ...
A continuous-wave-based acoustic method to measure viscoelastic properties of materials
(University of Missouri--Columbia, 2017)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Typical viscoelastic materials do not have a flat frequency response to mechanical vibrations. Viscoelastic property evaluations with a multi-frequency ...
Nanofibrillation of lignocellulosic biomass into lignin-containing nanocellulose for 3D printing and antimicrobial applications
(University of Missouri--Columbia, 2022)
Lignin-containing nanocellulose (LNC) has become an emerging subcategory of nanocellulose. Compared toedtraditional pure nanocellulose, LNC contains lignin and hemicellulose that are not fully removed from original ...
Modelling and analysis of energy metabolism in postmortem muscle
(University of Missouri--Columbia, 2022)
Fresh-meat quality is largely determined by a number of biochemical reactions during the conversion of muscle to meat. To produce consistent high-quality meat, it is necessary to have an understanding of energy metabolism ...
I. Infection control: exploration of siliceous zeolite MFI films as coatings for implantable devices II. Alternative approaches for post-operative infection control using pre-and pro-biotics: a meta-analysis
(University of Missouri--Columbia, 2022)
The prevention and control of infections associated with indwelling medical implants has remained a top goal for biomedical researchers and clinicians in associated fields. Multiple routes have been explored for this ...
Design and synthesis of targeted NIR fluorescent nanoparticles for bio-imaging
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] Breast cancer is the second most common cancer, and the chance that a woman will die from breast cancer is 2.6%. One in 8 women develop ...
Imaging structurual and mechanical properties in cardiovascular tissue using optical polarization tractography
(University of Missouri--Columbia, 2022)
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the US. Every 36 seconds, one person dies from CVD [1]. Structural deficiencies and secondary changes induced by either abnormal functioning ...
Tnf[alpha] alters occludin and endothelial cell barrier function : role of p38MAPK
(University of Missouri--Columbia, 2016)
Occludin is one of the key tight junction (TJ) proteins in endothelial cells and it plays an important role in modulating blood brain barrier (BBB) function. This protein (65kDa) has been shown to engage in many signaling ...
Engineering target nanomaterials for stable and efficient delivery of siRNA
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] Lung cancer has the highest cancer-related mortality rate in the United States. The most common form of lung cancer is non-small cell lung ...
Accurate DNA microsatellite and microRNA detection with a biological nanopore
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] Nanopore-based detection has been used in many genetic, epigenetic, proteomic, and bio-mechanism studies. In this report, we introduced two ...
Targeted therapeutics for non small cell lung carcinoma
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] "Lung carcinoma, also known as lung cancer, is a malignant tumor of lungs characterized by uncontrolled call growth in lung tissue. Tobacco smoking ...
Prediction of knee loading in native knee and total knee arthroplasty : a forward dynamics computational study
(University of Missouri--Columbia, 2019)
"The goal of this dissertation is to develop a musculoskeletal model and corroborate model predictions to experimentally measured in vivo knee contact forces, in order to study the biomechanical consequences of two different ...
Evaluation of a solid-liquid manure separation operation
(University of Missouri--Columbia, 2018)
Field monitoring and laboratory tests were conducted to evaluate the efficacy and practicality of a solid-liquid separation barn for finishing pigs. The solid-liquid separation system included a mechanical scraper and ...
Porous silicates for applications in smart water treatment systems and antimicrobial biomedical coatings
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Porous silicates, particularly ordered ones, may find novel and wide-ranging applications in the bioengineering arena in the near future. For instance, ...
Climate change impacts on hydrologic components and occurrence of drought in an agricultural watershed
(University of Missouri--Columbia, 2018)
The study on potential acceleration of future hydrologic cycle due to change in precipitation and increase in temperature are essential for managing natural resources and setting policy. The impact of future climate change ...
Imaging structural and mechanical properties of articular cartilage using optical polarization tractography
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Osteoarthritis (OA) is an extremely common joint disease, which affects more than one-third of all adults in the USA. Although the entire joint ...