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Development of electrospun synthetic bioabsorbable fibers for a novel bionanocomposite hernia repair material
(University of Missouri--Columbia, 2008)
In order to create a more durable and biocompatible hernia repair mesh, a novel bionanocomposite material based on the crosslinking of bioabsorbable polymer fibers to decellularized porcine diaphragm tissue is proposed. ...
Optical reflectance in fibrous tissues and skeletal muscles
(University of Missouri--Columbia, 2008)
We studied diffuse optical reflectance in two anisotropic biological tissues: high moisture soy extrudates and skeletal muscles. High moisture extrusion of soy proteins can produce healthy alternative protein sources that ...
Optical characterization of skeletal muscles
(University of Missouri--Columbia, 2007)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The optical absorption and reduced scattering coefficients of bulk skeleton muscle were measured by fitting the diffusion model to spatially resolved ...
Development of novel bionanocomposite scaffolds
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The development of three novel bionanocomposite scaffolds is presented in this dissertation. These scaffold materials are comprised of amine-functionalized ...
Porous silicates for applications in smart water treatment systems and antimicrobial biomedical coatings
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Porous silicates, particularly ordered ones, may find novel and wide-ranging applications in the bioengineering arena in the near future. For instance, ...
Study of human pupillary light reflex and its potential application in autism
(University of Missouri--Columbia, 2009)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Pupillary light reflex (PLR) can be used as an objective and non-invasive method to evaluate certain brain functions. In this research, we developed ...
I. Infection control: exploration of siliceous zeolite MFI films as coatings for implantable devices II. Alternative approaches for post-operative infection control using pre-and pro-biotics: a meta-analysis
(University of Missouri--Columbia, 2022)
The prevention and control of infections associated with indwelling medical implants has remained a top goal for biomedical researchers and clinicians in associated fields. Multiple routes have been explored for this purpose, including drug...
Natural and synthetic materials for the regeneration of osseous tissue
(University of Missouri--Columbia, 2017)
Bone is a complex tissue with many regulation mechanisms which can be taken advantage of through the release of simple signaling molecules delivered via a biodegradable material like a hydrogel. Hydrogels are water swollen ...
Development of tissue based biomaterials for articular cartilage injuries
(University of Missouri--Columbia, 2020)
Multiple biomaterials have been developed in this work. Decellularized porcine diaphragm extracellular matrix was homogenized and supplemented with various biomodulatory agents. It was developed as an injectable material ...
Photoacoustic discrimination of viable and thermally coagulated blood for burn injury imaging
(University of Missouri--Columbia, 2007)
, [mu]a, of thermally coagulated blood over the wavelength range from 580 to 700 nm. Additionally, we performed a linear regression on the 580 to 700 nm absorption spectrum and extrapolated it out to 500 nm, creating a theoretical 500 to 700 nm...
Quantification of cell attachment on different materials as candidate electrodes for measurement of quantal exocytosis
(University of Missouri--Columbia, 2008)
A high throughput lab-on-a-chip device is being developed for single cell capture for the purpose of high time resolution quantal exocytosis measurement with high probability of cell docking. This device makes use of DLC ...
Risk prediction and an injectable collagen material for intervertebral disc degeneration
(University of Missouri--Columbia, 2021)
This research primarily focuses on early prediction and treatment for intervertebral disc degeneration (IVDD). In Phase 1, machine learning algorithms were evaluated to predict the risk of intervertebral disc degeneration ...
In situ polymerizing collagen for the development of 3D printed tissue engineering scaffolds
(University of Missouri--Columbia, 2018)
Natural materials have been processed and utilized as scaffold materials in the field of tissue engineering for many years. One natural material often utilized is collagen since it is the main structural protein in mammalian ...
Methods of imaging articular cartilage under shear
(University of Missouri--Columbia, 2019)
Characterizing both the structure of articular cartilage, and its biomechanical properties is key to gaining a full understanding of how the tissue functions. Articular cartilage is an inhomogeneous tissue with a depth ...
Multi-scale self-assembly of nanoenergetic materials utilizing functionalized graphene
(University of Missouri--Columbia, 2020)
as discovering the science boundary of nanoenergetic materials. Micro-scale and macro-scale structured energetic composites were synthesized via self-assembly process between Al nanoparticles, metal oxide nanoparticles and functionalized graphene. A novel...
Effects of oxidative stress and Alzheimer's amyloid-beta peptide on astrocytes
(University of Missouri--Columbia, 2006)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Oxidative stress and deposition of amyloid-[beta] peptide (A[beta]) in brains have been hypothesized as causes of Alzheimer's disease (AD), and research ...
A fiber-optic confocal scanner for scattering tissue
(University of Missouri--Columbia, 2009)
Confocal microscopy has become an important diagnostic tool in examining scattering tissues. The high resolution of confocal microscopy and its optical sectioning capabilities lend itself as a desirable modality in examining ...
Optical stimulation of quantal exocytosis on transparent microchips
(University of Missouri--Columbia, 2007)
) film was sputter-deposited onto glass coverslips, which were then patterned into 24 cell-sized working electrodes (2̃0 [mu]m by 20 [mu]m). We loaded bovine chromaffin cells with acetoxymethyl (AM) ester derivatives of the Ca²⁺ cage NP-EGTA and Ca...
Development of a flexible image-based approach for studying signal transduction in isolated arterioles
(University of Missouri--Columbia, 2007)
Myogenic constriction in arterioles occurs when membrane tension leads to smooth muscle depolarization and voltage-gated calcium channel activation. A barrier to understanding the exact signaling events is the limited ...
Development of a capillary based helicobacter hepaticus biosensor
(University of Missouri--Columbia, 2006)
Helicobacter hepaticus causes hepatitis in mice. Infections with H. hepaticus can invalidate animal research studies and early detection helps curtail the spread of infection. The objective of this study was to develop a ...