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What are the indications for tonsillectomy in children?
(Family Physicians Inquiries Network, 2002)
. (Grade of recommendation: B, based on low-quality randomized controlled trials [RCTs]). The evidence supporting tonsillectomy for recurrence of sore throat is controversial. There is insufficient evidence to recommend other potential indications. (Grade...
Does evidence support the use of supplements to aid in BP control?
(Family Physicians Inquiries Network, 2020)
Q: Does evidence support the use of supplements to aid in BP control? Evidence-based answer: Yes. A number of well-tolerated natural therapies have been shown to reduce systolic and diastolic blood pressure (BP). (See TABLE1-8 for summary.) However...
What is the best beta-blocker for systolic heart failure?
(Family Physicians Inquiries Network, 2015)
Q: What is the best beta-blocker for systolic heart failure? Evidence-based answer: Three beta-blockers--carvedilol, metoprolol succinate, and bisoprolol--reduce mortality equally (by about 30% over one year) in patients with Class III or IV...
Is the ThinPrep better than conventional Pap smear at detecting cervical cancer?
(Family Physicians Inquiries Network, 2004)
the conventional Papanicolaou (Pap) smear at detecting cervical cancer (strength of recommendation [SOR]: A-, based on 1 large validating cohort study with a good reference standard and 1 systematic review). There is insufficient evidence to recommend 1 preparation...
Does caffeine intake during pregnancy affect birth weight?
(Family Physicians Inquiries Network, 2016)
Q: Does caffeine intake during pregnancy affect birth weight? Evidence-based answer: No. Reducing caffeinated coffee consumption by 180 mg of caffeine (the equivalent of 2 cups) per day after 16 weeks-gestation doesn't affect birth weight. Consuming...
Does using e-cigarettes cigarette smoking in adolescents?
(Family Physicians Inquiries Network, 2019)
Q: Does using e-cigarettes cigarette smoking in adolescents? Evidence-based answer: Probably. Electronic cigarette (e-cigarette) use by adolescents is associated with a 2- to 4-fold increase in cigarette smoking over the next year (strength...
Does withholding an ACE inhibitor or ARB before surgery improve outcomes?
(Family Physicians Inquiries Network, 2019)
Q: Does withholding an ACE inhibitor or ARB before surgery improve outcomes? EVIDENCE-BASED ANSWER: A GUARDED YES, because the evidence of benefit is from observational studies and applies to noncardiac surgery. Withholding angiotensin...
Do cinnamon supplements improve glycemic control in adults with T2DM?
(Family Physicians Inquiries Network, 2020)
Q: Do cinnamon supplements improve glycemic control in adults with T2DM? Evidence-based answer: the answer isn't clear. Cinnamon supplements for adults with type 2 diabetes haven't been shown to decrease hemoglobin A1C (strength of recommendation...
What are the risks of long-term PPI use for GERD symptoms in patients > 65 years?
(Family Physicians Inquiries Network, 2019)
Q: What are the risks of long-term PPI for GERD symptoms in patients > 65 years? EVIDENCE-BASED ANSWER: THE USE OF PROTON PUMP INHIBITORS (PPIs) to control gastrointestinal esophageal reflux disease (GRED) is significantly associated with increased...
Are antibiotics effective for otitis media with effusion?
(Family Physicians Inquiries Network, 2003)
rates. However, the most rigorous meta-analysis shows no benefit (strength of recommendation [SOR]: D, based on conflicting meta- analyses). No significant effect was noted on longer-term (>1 month) outcomes after treatment (SOR: A, based on a meta...
Treatment of Impetigo
(Family Physicians Inquiries Network, 2007)
of recommendation [SOR]: A) Based on the available evidence on effectiveness, no clear preference can be given for any one oral antibiotic over another. (SOR: A)...
What's best for IBS?
(Family Physicians Inquiries Network, 2012)
Recommend antispasmodics or antidepressants for patients with irritable bowel syndrome (IBS) and explain that, while fiber may have other benefits, it is unlikely to relieve IBS symptoms. Stength of recommendation: A: Based on a meta-analysis....
Does frenotomy help infants with tongue-tie overcome breastfeeding difficulties?
(Family Physicians Inquiries Network, 2015)
Q: Does frenotomy help infants with tongue-tie overcome breastfeeding difficulties? Evidence-based answer: Probably not. No evidence exists for improved latching after frenotomy, and evidence concerning improvements in maternal comfort...
Interventions for lower-extremity lymphedema
(Family Physicians Inquiries Network, 2013)
.) There is insufficient evidence about the safety and effectiveness of oral benzopyrones to determine whether they are useful for the treatment of lymphedema. (SOR: A, based on a systematic review.)...
What is the best way to diagnose polycystic ovarian syndrome?
(Family Physicians Inquiries Network, 2006)
Polycystic ovarian syndrome (PCOS) is diagnosed for women of childbearing age presenting with 2 of the following: 1)oligo- or anovulatory menstrual irregularities, 2) evidence of hyperandrogenism in the absence of secondary cause; 3) enlarged...
Chronic urticaria: What diagnostic evaluation is best?
(Family Physicians Inquiries Network, 2011)
(strength of recommendation: B, inconsistent or limited-quality evidence)....
Are oral agents effective for the treatment of verruca vulgaris?
(Family Physicians Inquiries Network, 2006)
Of the available oral therapies for common warts, none has sufficient evidence to recommend it as an effective therapy (strength of recommendation [SOR]: B). To date, no oral agent has been shown to be effective in a randomized, placebo...
Which detoxification regimens are effective for alcohol withdrawal syndrome?
(Family Physicians Inquiries Network, 2021)
Q: Which detoxification regimens are effective for alcohol withdrawal syndrom? Evidence based answer: Benzodiazepines remain the first-line regimen for alcohol withdrawal syndrome (AWS) and are the only class more effective than placebo for reducing...
Does birth weight predict childhood obesity?
(Family Physicians Inquiries Network, 2008)
A birth weight greater than 4,000 g is associated with an increased risk of obesity in both childhood and adolescence (strength of recommendation [SOR]: B, systematic review and multiple cohort studies).
What nonhormonal therapies are effective for postmenopausal vasomotor symptoms?
(Family Physicians Inquiries Network, 2003)
, and phenobarbital), methyldopa, evening primrose oil, maiquan, flaxseed, ginseng, and topical wild yam extract--have not been effective. Black cohosh may be effective, but the evidence for this is of poor quality (SOR: C)....