Clinical Inquiries (MU): Recent submissions
Now showing items 21-40 of 870
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Q Which injections are effective for lateral epicondylitis?
(Family Physicians Inquiries Network, 2021-11)Evidence-based answer: placebo injections actually improve lateral epicondylitis at high rates. No other injections convincingly improve it better than placebo. Corticosteroid injection is not superior to saline or anesthetic ... -
Q Does inadequate sleep increase obesity risk in children?
(Family Physicians Inquiries Network, 2021-12)Evidence-based answer: Yes, a link has been established but not a cause-effect relationship. Shorter reported sleep duration in childhood is associated with an increased risk of overweight or obesity years later (strength ... -
Q Is exercise therapy effective treatment for low back pain?
(Family Physicians Inquiries Network, 2021-11)Evidence-based answer: Yes, it is somewhat effective. Exercise therapy—including general exercise, yoga, Pilates, and motor control exercise—has been shown to modestly decrease pain in chronic low back pain (LBP); levels ... -
Q Do carotid artery calcifications seen on radiographs predict stenosis in asymptomatic adults?
(Family Physicians Inquiries Network, 2021-09)Evidence-based answer: not very well. In asymptomatic patients, carotid artery calcification seen on radiograph has a positive predictive value of 70% and a negative predictive value of 75% for carotid artery stenosis ... -
Q: Can family physicians accurately screen for AAA with point-of-care ultrasound?
(Family Physicians Inquiries Network, 7/8/2021)Evidence-based answer: LIKELY YES. Point-of-care ultrasound (POCUS) screening for abdominal aortic aneurysm (AAA) by nonradiologist physicians is 98% sensitive and 99% specific, compared with imaging performed by radiologists ... -
Q: Is event-driven PrEP dosing for HIV as effective as daily dosing?
(Family Physicians Inquiries Network, 2021-06)Evidence based answer: PROBABLY, although there are no head-to-head trials comparing the 2 dosing regimens. Event-driven pre-exposure prophylaxis (PrEP) dosing reduces HIV conversion by 86% compared to placebo (strength ... -
Q: Is NPH associated with fewer adverse events than analog basal insulin for adults with T2D?
(Family Physicians Inquiries Network, 2021-05)Evidence based answer: NO. Insulin glargine may lead to less patient-reported, symptomatic, and nocturnal hypoglycemia, although overall, there may not be a difference in the risk for severe hypoglycemia or hypoglycemia-related ... -
Q: Is ketamine effective and safe for treatment-resistant depression?
(Family Physicians Inquiries Network, 2021-04)Evidence-based answer: Maybe, but it’s too soon to tell. There is limited evidence that ketamine by itself is effective in the very short term. Single-dose intravenous (IV) ketamine is more likely than placebo (odds ratio ... -
Which detoxification regimens are effective for alcohol withdrawal syndrome?
(Family Physicians Inquiries Network, 2021)Q: Which detoxification regimens are effective for alcohol withdrawal syndrom? Evidence based answer: Benzodiazepines remain the first-line regimen for alcohol withdrawal syndrome (AWS) and are the only class more effective ... -
Is metformin effective for reducing weight in obese or overweight adolescents?
(Family Physicians Inquiries Network, 2021)Q: Is metformin effective for reducing weight in obese or overweight adolescents? Evidence based answer: Yes, to some degree—but it is of uncertain clinical significance. Over a period of 6 months, metformin modestly reduced ... -
Is the incidence of depressive disorders increased following cerebral concussion?
(Family Physicians Inquiries Network, 2021)Q: Is the incidence of depressive disorders increased following cerebral concussion? Evidence-based answer: yes, in some populations. Youth and adolescents with self-reported history of concussion had increased risk of ... -
Introduction to Clinical Inquiries : new series by the Family Physicians Inquiries Network
(Family Physicians Inquiries Network, 2020)Introduction to Clinical Inquiries and FPIN. The Clinical Inquiries were included in Canadian Family Physician beginning March 2020. -
Acupuncture for low back pain
(Family Physicians Inquiries Network, 2020)Clinical Inquiries question: Is acupuncture effective in improving pain relief for low back pain? Evidence-based answer: Acupuncture is an effective treatment for relief from low back pain, even when compared with other ... -
Efficacy of a low-carbohydrate or ketogenic diet in preventing patient morbidity and mortality
(Family Physicians Inquiries Network, 2020)Clinical Inquiries question: What is the efficacy of a low-carbohydrate or ketogenic diet in the prevention of patient morbidity and mortality? Evidence-based answer: Ketogenic diets can reduce seizure incidence in refractory ... -
Hypoglycemia with insulin and sulfonylureas
(Family Physicians Inquiries Network, 2020)Clinical Inquiries question: In patients with type 2 diabetes mellitus (T2DM), does the combination of insulin and sulfonylurea (SU) increase the risk of hypoglycemia? Evidence-based answer: The incidence of severe ... -
Chlamydia test-of-cure in pregnancy
(Family Physicians Inquiries Network, 2020)Clinical Inquiries question: What is the optimal interval between treatment and test-of-cure (TOC) in pregnant women with Chlamydia trachomatis (CT)? Evidence-based answer: The optimal interval between treatment and TOC ... -
Effect of corticosteroids on pain and function in knee osteoarthritis patients
(Family Physicians Inquiries Network, 2020)Clinical Inquiries question: Does the type of corticosteroid have an effect on pain and functional status of the knee in osteoarthritis (OA) patients receiving intra-articular injections? Evidence-based answer: In patients ... -
Effective analgesic options for intrauterine device placement pain
(Family Physicians Inquiries Network, 2020)Clinical Inquiries question: What analgesic options are most effective for pain related to intrauterine device (IUD) placement? Evidence-based answer: Lidocaine-prilocaine cream (LPC; 2.5% lidocaine and 2.5% prilocaine) ... -
Potential harms of long-term acne treatment with oral antibiotics
(Family Physicians Inquiries Network, 2020)Clinical Inquiries question: What are the potential harms of long-term acne treatment with oral antibiotics? Evidence-based answer: Specific evidence attributing adverse effects to long-term acne treatment with oral ... -
Effectiveness of dermoscopy in skin cancer diagnosis
(Family Physicians Inquiries Network, 2020)Clinical Inquiries question: Does dermoscopy improve the effectiveness of skin cancer diagnosis when used for skin cancer screening? Evidence-based answer: Dermoscopy added to visual inspection is more accurate than visual ...