The Family Physicians Inquiries Network is a community of inclusion that is committed to engaging every organization and individual who wishes to join us in revolutionizing primary care practice. The primary focus of the network is developing valuable benefits for family medicine departments, family practice residency programs and medical librarians/health sciences libraries.

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Recent Submissions

  • Antidepressant Tx for anxiety disorders: How long? 

    McGuire, Patricia; Castelli, Gregory (Family Physicians Inquiries Network, 2019)
    Antidepressant Tx for anxiety disorders: How long? This systematic review/meta-analysis provides some long-awaited evidence regarding the length of time to treat to minimize the risk of relapse. PRACTICE CHANGER: Keep ...
  • Do probiotics reduce C diff risk in hospitalized patients? 

    Simpson, Matthew; Lyon, Corey (Family Physicians Inquiries Network, 2019)
    Do probiotics reduce C diff risk in hospitalized patients? A systematic review and meta-analysis says, “Yes,” but that doesn’t necessarily mean they will start appearing on hospital formularies. Practice changer: Start ...
  • How safe and effective is ondansetron for nausea and vomiting in pregnancy? 

    Collins, Kimberly L.; Wilson, Megan; Vincent, E. Chris; Safranek, Sarah (2019)
    Q: How safe and effective is ondansetron for nausea and vomiting in pregnancy? Evidence-based answer: oral ondansetron is more effective than a combination of pyridoxine and doxylamine for outpatient treatment of nausea ...
  • Which oral nonopioid agents are most effective for OA pain? 

    Gilmer, Benjamin; Hulkower, Stephen; Wilson, Courtenay Gilmore; Macdonald, Brittney; Pozner, Jonathan; Stigleman, Sue (2019)
    Q Which oral nonopioid agents are most effective for OA pain? Evidence-based answer: nonsteroidal anti-inflammatory drugs (nsaids), when used at the maximum clinically effective dose, reduce osteoarthritis (OA) pain in ...
  • Do A-fib patients continue to benefit from vitamin K antagonists with advancing age? 

    Guthmann, Richard; Bahrami, Azita; Martin, Robert; Nashelsky, Joan (2019)
    Q Do A-fib patients continue to benefit from vitamin K antagonists with advancing age? Evidence-based answer: yes, patients with atrial fibrillation who are between the ages of 50 and 90 years continue to benefit from ...
  • Can unintended pregnancies be reduced by dispensing a year’s worth of hormonal contraception? 

    Wirsing, Nellie; Pierce, Carrie; Nashelsky, Joan (2019)
    Q Can unintended pregnancies be reduced by dispensing a year’s worth of hormonal contraception? Evidence-based answer: probably, although studies that looked directly at this outcome are limited. A systematic review showed ...
  • A better approach to the diagnosis of PE 

    Slattengren, Andrew H.; Prasad, Shailendra (Family Physicians Inquiries Network, 2019)
    A better approach to the diagnosis of PE: A simple diagnostic algorithm is all that’s needed to safely and effectively reduce our reliance on CT pulmonary angiography to diagnose PE. PRACTICE CHANGER: Do not order computed ...
  • How effective is spironolactone for treating resistant hypertension? 

    Lyon, Corey; Utter, Brigitte; DeSanto, Kristen (2019)
    Q: How effective is spironolactone for treating resistant hypertension? EVIDENCE-BASED ANSWER: VERY EFFECTIVE. Spironolactone reduces systolic blood pressure (SPB) by 11 to 17 mm Hg and diastolic blood pressure (DPB) by ...
  • Can vitamin D prevent acute respiratory infections? 

    Marshall, Bob; Bennett, Nick; Smith, Ashley; Robert, Oh; Burket, Jeffrey (Family Physicians Inquiries Network, 2019)
    Can vitamin D prevent acute respiratory infections? A systematic review and meta-analysis says Yes, but the dosages used may not be what you'd expect. PRACTICE CHANGER: Reduce acute respiratory tract infections in those ...
  • Does withholding an ACE inhibitor or ARB before surgery improve outcomes? 

    Jackman, Robert; Hamilton, Andrew (2019)
    Q: Does withholding an ACE inhibitor or ARB before surgery improve outcomes? EVIDENCE-BASED ANSWER: A GUARDED YES, because the evidence of benefit is from observational studies and applies to noncardiac surgery. Withholding ...
  • Should you switch the DAPT agent one month after ACS? 

    Ashby, Drew; Lyon, Corey (Family Physicians Inquiries Network, 2019)
    Should you switch the DAPT agent one month after ACS? A randomized controlled trial says “Yes,” but current guidelines say “No.” PRACTICE CHANGER: Switch to clopidogrel from one of the newer P2Y12 blockers 1 ...
  • What are the risks of long-term PPI use for GERD symptoms in patients > 65 years? 

    Devitt, Jessica; Lyon, Corey; Swanson, Sarah Beth; DeSanto, Kristen (2019)
    Q: What are the risks of long-term PPI for GERD symptoms in patients > 65 years? EVIDENCE-BASED ANSWER: THE USE OF PROTON PUMP INHIBITORS (PPIs) to control gastrointestinal esophageal reflux disease (GRED) is significantly ...
  • Bariatric surgery plus medical therapy : effective Tx for T2DM? 

    Roberson, Kortnee Y.; Van Gompel, Emily White; Jarret, Jennie B. (Family Physicians Inquiries Network, 2019-03)
    Bariatric surgery + medical therapy: Effective Tx for T2DM? Short-term studies have indicated “Yes,” but does a longterm randomized controlled trial give it a thumbs up? PRACTICE CHANGER: Consider bariatric surgery with ...
  • How do these 3 diabetes agents compare in reducing mortality? 

    Martini, Jennifer; Coe, Catherine L.; Mounsey, Anne (Family Physicians Inquiries Network, 2019-03)
    How do these 3 diabetes agents compare in reducing mortality? A meta-analysis reveals that there may be advantages associated with SGLT-2 inhibitors and GLP-1 agonists that are not associated with DPP-4 inhibitors. PRACTICE ...
  • Is intra-articular platelet-rich plasma injection an effective treatment for knee OA? 

    Wilcox, Carrie Lynn; Safranek, Sarah (2019-03)
    Q: Is intra-articular platelet-rich plasma injection an effective treatment for knee OA? EVIDENCE-BASED ANSWER: PROBABLY NOT, based on the balance of evidence. While low-quality evidence may suggest potential benefit, the ...
  • Does left atrial appendage closure reduce stroke rates as well as oral anticoagulants and antiplatelet meds in A-fib patients? 

    Careyva, Beth; Keister, Drew; Mathieu, Susan; Wilson, Lynn; Nashelsky, Joan (2019-01)
    Q: Does left atrial appendage closure reduce stroke rates as well as oral anticoagulants and antiplatelet meds in A-fib patients? EVIDENCE-BASED ANSWER: Yes. Left atrial appendage closure (LAAC) with the Watchman device ...
  • Less is more when it comes to ketorolac for pain 

    Lyon, Corey; Claus, Liza W. (Family Physicians Inquiries Network, 2019-02)
    Less is more when it comes to ketorolac for pain. It’s time to review our dosing with ketorolac for acute pain management. PRACTICE CHANGER: Using a low dose (10 mg) of intravenous ketorolac for moderate to severe acute ...
  • What’s the best treatment setting for stable PE patients? 

    Schaffer, Monica; Castelli, Gregory (Family Physicians Inquiries Network, 2018-12)
    What’s the best treatment setting for stable PE patients? The answer seems to be the outpatient setting. Here’s why. PRACTICE CHANGER: Manage patients with acute pulmonary embolism (PE) who are hemodynamically stable in ...
  • Does amniotomy shorten spontaneous labor or improve outcomes? 

    Worthley, Megan; Kelsberg, Gary; Safranek, Sarah (2018-12)
    Q: Does amniotomy shorten spontaneous labor or improve outcomes? Evidence-based answer: No. Amniotomy neither shortens spontaneous labor nor improves any of the following outcomes: length of first stage of labor, cesarean ...
  • Should you reassess your patient’s asthma diagnosis? 

    Stevermer, James J.; Hayes, Alisa (Family Physicians Inquiries Network, 2018-11)
    Should you reassess your patient's asthma diagnosis? Asthma may not be a permanent diagnosis in adults. A study finds that up to one-third of adults with physician-diagnosed asthma no longer had it after 5 years. ...

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