Browsing Theses (MU) by Thesis Department "Veterinary biomedical sciences (MU)"
Now showing items 21-40 of 47
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Gold nanoparticle-biomolecule conjugates : synthesis, properties, cellular interactions and cytotoxicity studies
(University of Missouri--Columbia, 2008)This research focuses on conjugation of two major biomolecules i.e., Bombesin and Annexin V, to AuNps and studying their target specificity. The target specificity of AuNps coated with Bombesin, a GRP receptor specific ... -
Immunomodulators in feline asthma
(University of Missouri--Columbia, 2010)Experimental asthma was induced in 10 cats using Bermuda grass allergen (BGA) and cats were randomly selected to receive either feG (1 mg/kg, PO) or saline for 2 weeks, followed by a 2 week washout period before receiving ... -
Immunomodulatory effects of opioids
(University of Missouri--Columbia, 2010)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Opioids have been shown to modulate the immune system in animal models by affecting both the acquired and innate arms of the immune system. Many of ... -
In vitro evaluation of veterinary and human suture anchors in metaphyseal bone of the canine tibia
(University of Missouri--Columbia, 2006)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Suture anchors, also called bone or tissue anchors, provide orthopedic surgeons a mechanism for secure fixation of soft tissues to bone. A human system ... -
The mechanism of C-type natriuretic peptide production in dogs and its use as a prognostic indicator in critically ill dogs
(University of Missouri--Columbia, 2012)The N-terminal portion of pro C-type natriuretic peptide (NT-pCNP) has shown promise as a diagnostic biomarker for sepsis in humans and dogs. The mechanism of NT-pCNP induction and its use as a prognostic indicator in dogs ... -
Metabolic responses to a westernized diet administered to rats selectively bred for high and low amounts of voluntary exercise
(University of Missouri--Columbia, 2015)Introduction: The purpose of my study was to determine if rats with varying levels of inherent motivation to voluntarily run in wheels, when given no access to voluntary running wheels, would retain any protective affects ... -
A missense mutation in Atf2 in standard poodles with fatal neonatal encephalopathy
(University of Missouri--Columbia, 2007)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Neonatal encephalopathy with seizures (NEWS) is a previously undescribed autosomal recessive disease in Standard Poodles. Affected puppies are small ... -
Molecular epidemiology of tick-borne Anaplasmataceae among client-owned dogs in Missouri
(University of Missouri--Columbia, 2012)Several tick-borne agents of zoonotic ehrlichiosis or anaplasmosis are endemic to Missouri. Dogs are susceptible to the same infections and tick vectors, but their roles as models, sentinels or reservoirs are undefined. ... -
Neurokinin-1 antagonism as a novel treatment for feline asthma : investigation of the role of substance p in airflow limitation and airway inflammation
(University of Missouri--Columbia, 2018)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Feline asthma, a chronic respiratory condition, results cough and/or episodic respiratory distress induced by airway hypperresponsiveness (AHR), airway ... -
New strategies in canine corneal wound healing for the veterinary ophthalmic patient
(University of Missouri--Columbia, 2012)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Canine corneal fibrosis is a significant clinical problem in veterinary ophthalmology. Corneal wound healing following injury or infection often results ... -
Noonan Syndrome with multiple lentigines : insights into hypertrophy and hypercontractility
(University of Missouri--Columbia, 2015)Noonan Syndrome with Multiple Lentigines (NSML) is a rare genetic disease resulting in a phenotype with specific features, most importantly left ventricular cardiac hypertrophy. The majority of NSML cases result from ... -
A novel approach to the clinical diagnosis and treatment of canine histiocytic sarcoma
(University of Missouri--Columbia, 2017)This work provides a review of canine histiocytic sarcoma (HS) including background immunology, diagnosis, treatment, and prognosis. Given the poor prognosis of HS compared to other soft tissue sarcomas in dogs, the research ... -
Osteochondral allograft preservation in a serum-free chemically-defined media
(University of Missouri--Columbia, 2011)Articular cartilage has a very limited capacity as compared to other biological tissues to repair and regenerate because of its avascular nature. Chronic degradation of articular cartilage may result in osteoarthritis, the ... -
Paradoxical dysuria among dogs with degenerative lumbosacral stenosis
(University of Missouri--Columbia, 2011)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Degenerative lumbosacral stenosis (DLSS) is a multifactorial condition affecting predominantly large breed dogs. The combination of stenosis and ... -
Parenteral fish oil effects on plasma non-esterified fatty acids and systemic cytokine concentrations in dogs immediately following ovariohysterectomy
(University of Missouri--Columbia, 2012)An extreme systemic inflammatory response may be observed in dogs that experience severe accidental trauma, such as being struck by a car. The inflammatory response may be so extreme that it complicates treatment and causes ... -
Pathogenicity of Helicobacter ganmani infection in Helicobacter susceptible and resistant mice
(University of Missouri--Columbia, 2014)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Helicobacter species are one of the most prevalent bacterial contaminants of laboratory rodents. It is currently unknown whether Helicobacter ganmani, ... -
Preclinical evaluation of 177Lu-BBR2 antagonist radiothearpy of prostate cancer
(University of Missouri--Columbia, 2013)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Castration resistant prostate cancer (CRPC) is the second most common cause of cancer death in the United States. Current treatment protocols offer ... -
Prevalence of Staphylococcus aureus and MRSA carriage in three populations
(University of Missouri--Columbia, 2008)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] A higher prevalence of methicillin-resistant Staphylococcus aureus (MRSA) colonization has been reported in healthcare workers than in non-healthcare ... -
The role of CFTR in regulating the cell cycle of intestinal stem cells
(University of Missouri--Columbia, 2016)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] [Abstract taken from public pdf.] Cystic fibrosis (CF) patients and CF mouse models have an increased risk for gastrointestinal (GI) cancer. Intestinal ... -
Specific neuronal phenotypes within the rostral ventrolateral medulla following cardiovascular deconditioning in rats
(University of Missouri--Columbia, 2008)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Humans exposed to prolonged periods of bed rest or spaceflight undergo multiple cardiovascular adaptations including a predisposition for orthostatic ...