Department of Biological Engineering (MU)
Biological Engineering is a science-based engineering discipline that integrates engineering and biological sciences in one curriculum. Biological engineers develop products and design systems or processes for improved human health, use of bio-resources, and protection of the environment.
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Engineering nanomaterials for cancer theranostics
(University of Missouri--Columbia, 2021)This thesis aims to engineer novel nanomaterial to target receptors on the surface of cancer to diagnose and deliver cytotoxic drugs or siRNA selectively. Receptor-targeting peptides have been relatively unexplored to ... -
Improvement of co-digesting swine manure and waste kitchen oil
(University of Missouri--Columbia, 2021)Anaerobic co-digestion of swine manure (SM) and waste kitchen oil (WKO) was conducted to evaluate the effect of substrate loading rates on biogas production efficiency. Biogas yields of M4O2 (4 g-VSSM L-1 d-1 + 2 g-VSWKO ... -
Discovery, design, and optimization of implantable/wearable, wireless biosensors
(University of Missouri--Columbia, 2022)[EMBARGOED UNTIL 6/1/2023] In the world of wireless technology, communication, power supply, and response time of the sensors are the focal points of device design. Bluetooth and Near-Field-Communication (NFC) are two ... -
Enhanced tissue engineering properties of osteoinductive chitosan hydrogel
(University of Missouri--Columbia, 2022)[EMBARGOED UNTIL 6/1/2023] Lower back pain is a considerable medical problem that will impact 80 percent of the U.S. population at some point in their life. With the most severe cases, surgical repair is necessary and is ... -
Methods for improved kinematic measurements of the lower extremities
(University of Missouri--Columbia, 2022)An understanding of knee dynamics is vital to treat neurological and musculoskeletal conditions that affect the lower extremities and achieve peak performance from athletes. To obtain and analyze kinematics and kinetics ... -
From biomass to wearable devices: laser-induced graphene derived from lignin for ultrasensitive sensing
(University of Missouri--Columbia, 2021)Laser-indued graphene (LIG) is 3D porous structure with many promising properties. Lignin-based precursor has shown its unique properties in generating high quality LIG among various organic carbon-based substrates. In ... -
Risk prediction and an injectable collagen material for intervertebral disc degeneration
(University of Missouri--Columbia, 2021)This research primarily focuses on early prediction and treatment for intervertebral disc degeneration (IVDD). In Phase 1, machine learning algorithms were evaluated to predict the risk of intervertebral disc degeneration ... -
Lignin dissolution in deep eutectic solvents : a molecular dynamics study
(University of Missouri--Columbia, 2020)Deep eutectic solvents (DESs) have shown great potential on lignocellulosic biomass pretreatment. Many DESs are capable of extracting lignin from biomass and dissolving hemicellulose while preserving most of cellulose in ... -
Development of tissue based biomaterials for articular cartilage injuries
(University of Missouri--Columbia, 2020)Multiple biomaterials have been developed in this work. Decellularized porcine diaphragm extracellular matrix was homogenized and supplemented with various biomodulatory agents. It was developed as an injectable material ... -
Using (microchannel) electrochemical impedance spectroscopy to detect bacterial activities
(University of Missouri--Columbia, 2020)Even though rapid detection of molecular methods has been used in bacterial detection, (automated) liquid culture methods are still the "Gold Standard" for the detection of living bacteria, especially in cases where there ... -
Degradation of the veterinary antibiotics in swine manure via anaerobic digestion
(University of Missouri--Columbia, 2021)Antimicrobial resistance is becoming an imminent danger for human health, in part because of excessive consumption of antibiotics in the animal industry. Laboratory-scale anaerobic digesters (ADs) were utilized to investigate ... -
Quantifying the effect of environments on crop emergence, development and yield using sensing and deep learning techniques
(University of Missouri--Columbia, 2021)The world population is estimated to increase by 2 billion in the next 30 years, and global crop production needs to double by 2050 to meet the projected demands from rising population, diet shifts, and increasing biofuels ... -
Development of UAV-based high-throughput phenotyping technologies towards improving soybean breeding efficiency
(University of Missouri--Columbia, 2021)Development of new crop varieties with improved traits through crop breeding programs is one of the promising solutions for the estimated food crisis in 2050 when agricultural production needs to double its current growth ... -
Four-limb IMU sensors for canine gait analysis
(University of Missouri--Columbia, 2019)Canine models of human musculoskeletal diseases, such as Duchenne muscular dystrophy (DMD), are important translational animal models for developing therapies. Musculoskeletal diseases alter gait performance, and gait ... -
The impact of adverse maternal environments on resistance artery function and mechanical characteristics in offspring
(University of Missouri--Columbia, 2020)Cardiovascular disease is one of the leading causes of death worldwide. Maternal obesity, gestational diabetes mellitus (GMD) and assisted reproductive technologies (ART) have been associated with cardiovascular deficiencies ... -
Targeted therapeutics for non small cell lung carcinoma
(University of Missouri--Columbia, 2019)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] "Lung carcinoma, also known as lung cancer, is a malignant tumor of lungs characterized by uncontrolled call growth in lung tissue. Tobacco smoking ... -
Use of geographic information systems and remote sensing as automated tool for variable rate irrigation prescriptions
(University of Missouri--Columbia, 2019)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Economic as well as water shortage pressure on agricultural use of water has placed added emphasis on efficient irrigation management. Center pivot ... -
Multi-scale self-assembly of nanoenergetic materials utilizing functionalized graphene
(University of Missouri--Columbia, 2020)The work described here-in focuses on the synthesis and characterization of novel nanoenergetic materials and is driven by overcoming the disadvantages of traditional nanoenergetic composites, improving the energetic ... -
Imaging structural and mechanical properties of articular cartilage using optical polarization tractography
(University of Missouri--Columbia, 2019)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Osteoarthritis (OA) is an extremely common joint disease, which affects more than one-third of all adults in the USA. Although the entire joint ... -
Engineering target nanomaterials for stable and efficient delivery of siRNA
(University of Missouri--Columbia, 2019)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] Lung cancer has the highest cancer-related mortality rate in the United States. The most common form of lung cancer is non-small cell lung ...