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Now showing items 41-60 of 183
Lignin dissolution in deep eutectic solvents : a molecular dynamics study
(University of Missouri--Columbia, 2020)
Deep eutectic solvents (DESs) have shown great potential on lignocellulosic biomass pretreatment. Many DESs are capable of extracting lignin from biomass and dissolving hemicellulose while preserving most of cellulose in ...
The impact of adverse maternal environments on resistance artery function and mechanical characteristics in offspring
(University of Missouri--Columbia, 2020)
Cardiovascular disease is one of the leading causes of death worldwide. Maternal obesity, gestational diabetes mellitus (GMD) and assisted reproductive technologies (ART) have been associated with cardiovascular deficiencies ...
Development of UAV-based high-throughput phenotyping technologies towards improving soybean breeding efficiency
(University of Missouri--Columbia, 2021)
Development of new crop varieties with improved traits through crop breeding programs is one of the promising solutions for the estimated food crisis in 2050 when agricultural production needs to double its current growth ...
Direct-from-sputum rapid phenotypic drug susceptibility test for mycobacteria
(University of Missouri--Columbia, 2018)
The spread of multi-drug resistant tuberculosis (MDR-TB) is a leading global public-health challenge. Because not all biological-mechanisms of resistance are known, culture-based (phenotypic) drug-susceptibility testing ...
Four-limb IMU sensors for canine gait analysis
(University of Missouri--Columbia, 2019)
Canine models of human musculoskeletal diseases, such as Duchenne muscular dystrophy (DMD), are important translational animal models for developing therapies. Musculoskeletal diseases alter gait performance, and gait ...
From biomass to wearable devices: laser-induced graphene derived from lignin for ultrasensitive sensing
(University of Missouri--Columbia, 2021)
Laser-indued graphene (LIG) is 3D porous structure with many promising properties. Lignin-based precursor has shown its unique properties in generating high quality LIG among various organic carbon-based substrates. In ...
Engineering nanomaterials for cancer theranostics
(University of Missouri--Columbia, 2021)
This thesis aims to engineer novel nanomaterial to target receptors on the surface of cancer to diagnose and deliver cytotoxic drugs or siRNA selectively. Receptor-targeting peptides have been relatively unexplored to ...
Methods for improved kinematic measurements of the lower extremities
(University of Missouri--Columbia, 2022)
An understanding of knee dynamics is vital to treat neurological and musculoskeletal conditions that affect the lower extremities and achieve peak performance from athletes. To obtain and analyze kinematics and kinetics ...
Risk prediction and an injectable collagen material for intervertebral disc degeneration
(University of Missouri--Columbia, 2021)
This research primarily focuses on early prediction and treatment for intervertebral disc degeneration (IVDD). In Phase 1, machine learning algorithms were evaluated to predict the risk of intervertebral disc degeneration ...
Development of tissue based biomaterials for articular cartilage injuries
(University of Missouri--Columbia, 2020)
Multiple biomaterials have been developed in this work. Decellularized porcine diaphragm extracellular matrix was homogenized and supplemented with various biomodulatory agents. It was developed as an injectable material ...
Design and synthesis of targeted NIR fluorescent nanoparticles for bio-imaging
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] Breast cancer is the second most common cancer, and the chance that a woman will die from breast cancer is 2.6%. One in 8 women develop ...
Discovery, design, and optimization of implantable/wearable, wireless biosensors
(University of Missouri--Columbia, 2022)
In the world of wireless technology, communication, power supply, and response time of the sensors are the focal points of device design. Bluetooth and Near-Field-Communication (NFC) are two excellent methods of communication ...
Using (microchannel) electrochemical impedance spectroscopy to detect bacterial activities
(University of Missouri--Columbia, 2020)
Even though rapid detection of molecular methods has been used in bacterial detection, (automated) liquid culture methods are still the "Gold Standard" for the detection of living bacteria, especially in cases where there ...
Accurate DNA microsatellite and microRNA detection with a biological nanopore
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] Nanopore-based detection has been used in many genetic, epigenetic, proteomic, and bio-mechanism studies. In this report, we introduced two ...
Multi-scale self-assembly of nanoenergetic materials utilizing functionalized graphene
(University of Missouri--Columbia, 2020)
The work described here-in focuses on the synthesis and characterization of novel nanoenergetic materials and is driven by overcoming the disadvantages of traditional nanoenergetic composites, improving the energetic ...
A continuous-wave-based acoustic method to measure viscoelastic properties of materials
(University of Missouri--Columbia, 2017)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Typical viscoelastic materials do not have a flat frequency response to mechanical vibrations. Viscoelastic property evaluations with a multi-frequency ...
Use of geographic information systems and remote sensing as automated tool for variable rate irrigation prescriptions
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Economic as well as water shortage pressure on agricultural use of water has placed added emphasis on efficient irrigation management. Center pivot ...
Automatic four-limb IMU gait analysis in the canine DMD model
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Gait analysis is valuable for studying neuromuscular and skeletal diseases. Wearable motion sensors or inertial measurement units (IMUs) possess ...
Evaluation of the antimicrobial properties and biocompatibility of polypropylene mesh conjugated with gold nanoparticles
(University of Missouri--Columbia, 2013)
Polypropylene (PP) mesh is commonly utilized as a patch for hernia repairs and for pelvic slings. However, biocompatibility and infection rates are a concern. Conjugating gold nanoparticles (AuNPs) to PP mesh may enhance ...
Multi-frequency electrical impedance method for detection of viable micro-organisms, their quantification and their characterization
(University of Missouri--Columbia, 2013)
Despite advances in DNA based technologies and molecular methods, there are still several drawbacks to these methods and hence, there is a need for development of a new technology for microbial detection and quantification. ...