RSS 1.0Priority Updates to Research Literature (PURLs)
Priority Updates from the Research Literature (PURLs) distill the literature to those few articles that are relevant, practice-changing, and able to be implemented immediately. They generate new evidence-based recommendations for practice for family physicians and other primary care clinicians. PURLs are published exclusively in the Journal of Family Practice.
Items in MOspace are protected by copyright, with all rights reserved, unless otherwise indicated.
Recent Submissions
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A new protocol for RhD-negative pregnant women?
(Family Physicians Inquiries Network, 2018-05)Can cell-free DNA testing reduce unnecessary use of anti-D immunoglobulin in RhD-negative women and still prevent harm to their RhD-positive infants? PRACTICE CHANGER: Employ cell-free DNA testing at 27 weeks’ gestation ... -
Treating migraines : it's different for kids
(Family Physicians Inquiries Network, 2018-04)Treating migraines: It’s different for kids Certain medications used for migraine prevention in adults do not perform the same way in children and adolescents and can actually cause harm. PRACTICE CHANGER: Do not prescribe ... -
An easy approach to obtaining clean-catch urine from infants
(Family Physicians Inquiries Network, 2018-03)An easy approach to obtaining clean-catch urine from infants Current collection methods leave much to be desired. But a new method may provide a quick alternative. Apply gauze soaked in cold sterile saline to the suprapubic ... -
Does fish oil during pregnancy help prevent asthma in kids?
(Family Physicians Inquiries Network, 2018-02)Does fish oil during pregnancy help prevent asthma in kids? The evidence on fish oil has been mixed, but this study affirms its benefits—in certain women. PRACTICE CHANGER: Fish oil supplementation taken by women in the ... -
Tamsulosin for patients with ureteral stones?
(Family Physicians Inquiries Network, 2018-01)Tamsulosin for patients with ureteral stones? Yes, but only for some. Find out which of your patients can benefit. PRACTICE CHANGER: Prescribe tamsulosin for stone expulsion in patients with distal ureteral stones 5 to 10 ... -
Does azithromycin have a role in cesarean sections?
(Family Physicians Inquiries Network, 2017-12)Does azithromycin have a role in cesarean sections? Yes, adding azithromycin to the usual antibiotic protocol in nonelective c-sections reduces infections. But not everyone can take advantage of it. PRACTICE CHANGER: ... -
The benefits—and limits— of PPIs with warfarin regimens
(Family Physicians Inquiries Network, 2017-11)Patients on warfarin + antiplatelet/NSAID regimens are likely to benefit from the gastroprotective effect of PPIs. For patients taking warfarin alone, it’s a different story. PRACTICE CHANGER: Prescribe a proton pump ... -
When to "CAP" off treatment for pneumonia
(Family Physicians Inquiries Network, 2017-10)Is 5 days of antibiotic therapy really sufficient for adults hospitalized with community-acquired pneumonia? PRACTICE CHANGER: Prescribe 5 days of antibiotic treatment for inpatients with community-acquired pneumonia ... -
SSRIs for depression/heart failure patients? Not so fast
(Family Physicians Inquiries Network, 2017-09)This study should put to rest the practice of starting SSRIs in depressed patients with heart failure in an attempt to affect CVD outcomes. PRACTICE CHANGER: Do not prescribe selective serotonin reuptake inhibitors to ... -
Direct oral anticoagulants or warfarin for A fib?
(Family Physicians Inquiries Network, 2017-08)A recent study evaluated the effectiveness of 3 direct oral anticoagulants and warfarin in patients with atrial fibrillation. So which agents came out on top? PRACTICE CHANGER: Use direct oral anticoagulants instead of ... -
Which combined OC to prescribe with CV safety in mind?
(Family Physicians Inquiries Network, 2017)When prescribing combined oral contraceptives, choose one containing levonorgestrel and low-dose estrogen (20 mcg) to minimize the risks of pulmonary embolism, ischemic stroke, and myocardial infarction. -
Oral agent offers relief from generalized hyperhidrosis
(Family Physicians Inquiries Network, 2017)Hyperhidrosis is a common, self-limiting problem affecting 2% to 3% of the population in the United States. Patients may complain of localized sweating of the hands, feet, face, or underarms or more systemic, generalized ... -
Consider melatonin for migraine prevention
(Family Physicians Inquiries Network, 2017)An effective migraine prevention alternative with minimal adverse effects Melatonin is an accessible and affordable option for preventing migraine headaches in chronic sufferers. -
When can exercise supplant surgery for degenerative meniscal tears?
(Family Physicians Inquiries Network, 2017-04)When can exercise supplant surgery for degenerative meniscal tears? PRACTICE CHANGER: Recommend supervised exercise therapy to your patients with a medial, degenerative meniscal tear and a minimal history of osteoarthritis ... -
"Cold turkey" works best for smoking cessation
(Family Physicians Inquiries Network, 2017-03)"Cold turkey" works best for smoking cessation. PRACTICE CHANGER: Counsel patients who want to quit smoking that abrupt smoking cessation is more effective for long-term abstinence than taking a gradual approach. STRENGTH ... -
Steroids during late preterm labor: better later than never
(Family Physicians Inquiries Network, 2017-02)Steroids during late preterm labor: Better later than never. Steroids—even when administered in the last leg of the late preterm period—still reduce the likelihood of respiratory complications in newborns. Practice changer: ... -
Need an add-on to metformin? Consider this
(Family Physicians Inquiries Network, 2017-01)Need an add-on to metformin? Consider this. Sulfonylureas have been the preferred add-on therapy to metformin for T2DM, but a study finds that DPP-4s have lower risks of death, CV events, and hypoglycemia. Practice changer: ... -
A more palatable alternative to oral rehydration therapy for kids
(Family Physicians Inquiries Network, 2016-12)A more palatable alternative to oral rehydration therapy for kids. Parents no longer need to struggle to get their kids to drink electrolyte solutions during episodes of mild gastroenteritis; apple juice works just as well. ... -
Monitoring home BP readings just got easier
(Family Physicians Inquiries Network, 2016-10)Monitoring home BP readings just got easier. This novel method of identifying patients with uncontrolled hypertension correlates well with ambulatory BP monitoring. Practice changer: Use this easy "3 out of 10 rule" to ... -
Deliver or wait with late preterm membrane rupture?
(Family Physicians Inquiries Network, 2016-11)Deliver or wait with late preterm membrane rupture? While ACOG recommends delivery for all women with ruptured membranes after 34 weeks' gestation, a new study finds expectant management may be the way to go. Practice ...