Browsing 2016 MU dissertations - Freely available online by Thesis Department "Microbiology (Medicine) (MU)"
Now showing items 1-5 of 5
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Cell-to-cell infection, cell-cell fusion and production of ebolavirus : mechanisms of action and cellular modulators
(University of Missouri--Columbia, 2016)Ebolavirus (EBOV), a member of the Filoviridae family, is a deadly non-segment negative-sense RNA virus that causes hemorrhagic fever among human and other species; the fatality rate can be up to 80%. In 2014, a re-emergent ... -
The cellular and humoral immune response against primary infection with Coxiella burnetii
(University of Missouri--Columbia, 2016)Coxiella burnetii infection in mice results in a limited febrile illness that can be measured by examining splenomegaly, bacterial burden, and histopathology. In humans, this disease is known as Q fever. Using the mouse ... -
Delineation of Duchenne muscular dystrophy gene therapy using genetically engineered mice
(University of Missouri--Columbia, 2016)Duchenne muscular dystrophy (DMD) is a genetically inherited debilitating muscle disorder affecting young boys due to the loss of dystrophin protein in muscle and the heart. Affected individuals lose their mobility and ... -
Mechanisms of clostridial neurotoxin binding and entry
(University of Missouri--Columbia, 2016)The botulinum neurotoxins (BoNTs) and tetanus neurotoxin (TeNT) make up the clostridial neurotoxin (CNT) family. The CNTs are produced by Clostridium botulinum and Clostridum tetani respectively, and are the most potent ... -
Structural and functional characterization of Clostridium difficile toxin B binding and entry
(University of Missouri--Columbia, 2016)Clostridium difficile (C. difficile) has recently emerged as a worldwide nosocomial and iatrogenic infection. C. difficile is a gram-positive, motile bacillus whose sporulation ability significantly contributes to its ...