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dc.contributor.advisorHaidekker, Mark A., 1963-eng
dc.contributor.authorLaCroix, Jeffrey T., 1983-eng
dc.date.issued2009eng
dc.date.submitted2009 Springeng
dc.descriptionTitle from PDF of title page (University of Missouri--Columbia, viewed on Feb 15, 2010).eng
dc.descriptionThe entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file.eng
dc.descriptionDissertation advisor: Dr. Mark A. Haidekker.eng
dc.descriptionVita.eng
dc.descriptionIncludes bibliographical references.eng
dc.descriptionPh. D. University of Missouri--Columbia 2009.eng
dc.descriptionDissertations, Academic -- University of Missouri--Columbia -- Biological engineering.eng
dc.description.abstractConfocal microscopy has become an important diagnostic tool in examining scattering tissues. The high resolution of confocal microscopy and its optical sectioning capabilities lend itself as a desirable modality in examining structures on the micrometer scale. While commercial confocal microscopes are readily available, they may not be suitable for examining tissues in vivo or able to accommodate large samples. The presented work offers a prototype device based on the principle of confocal microscopy that is versatile enough to be used not only as a small scale scanner, but adaptable for a wide range of situations. The automated capabilities of the scanner allow it to be used as a method of thickness measurement for tissue engineered cell sheets, in vivo examination of skin, and determining homogeneity in scattering tissues. The abilities and shortcomings of the device are investigated, and future adaptations of the device are proposed.eng
dc.format.extentxv, 129 pageseng
dc.identifier.oclc518096678eng
dc.identifier.urihttps://hdl.handle.net/10355/6153
dc.identifier.urihttps://doi.org/10.32469/10355/6153eng
dc.languageEnglisheng
dc.publisherUniversity of Missouri--Columbiaeng
dc.relation.ispartofcollectionUniversity of Missouri--Columbia. Graduate School. Theses and Dissertationseng
dc.source.originalSubmitted by University of Missouri--Columbia Graduate School.eng
dc.subject.lcshConfocal microscopyeng
dc.subject.lcshLight -- Scatteringeng
dc.subject.lcshTissueseng
dc.titleA fiber-optic confocal scanner for scattering tissueeng
dc.typeThesiseng
thesis.degree.disciplineBiological engineering (MU)eng
thesis.degree.grantorUniversity of Missouri--Columbiaeng
thesis.degree.levelDoctoraleng
thesis.degree.namePh. D.eng


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