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Applications of gel electrophoresis in quantum dot conjugates' separation and purification
(University of Missouri--Columbia, 2009)
The objectives of this study were to build Quantum dot (QD) crosslinker complexes for antibody conjugation usage, to purify QD crosslinker complexes by gel electrophoresis and to check the biological functionalities of ...
Development of a post-traumatic osteoarthritis model to evaluate the effects of impact velocity and maximum strain on articular cartilage cell viability, matrix biomarkers, and material properties
(University of Missouri--Columbia, 2009)
Post-traumatic osteoarthritis (PTOA) is a very painful and debilitating disease that is associated with mechanical injury to articular cartilage, yet the severity of trauma required to induce it is unknown. The objective ...
Modeling of delayed fluorescence from photosystem II and applications in assessment of drought and chemical stresses
(University of Missouri--Columbia, 2009)
Photosynthesis is not only vital for plant growth and survival but also indicative of plant-environment interactions. This research was designed to analyze photoelectron kinetics and its dependence on environmental factors. ...
Detection of cold flow properties of diesel and biodiesel fuel using optical sensor
(University of Missouri--Columbia, 2006)
Identification of cloud point for biodiesel fuel can be used to optimize the performance of biodiesel fueled vehicles in cold weather. Cloud point is the temperature at which the smallest cluster of wax crystal is observed ...
Nano- and micro-scale studies of exocytosis
(University of Missouri--Columbia, 2007)
Neurons and neuroendocrine cells contain vesicles packed with hormones or neurotransmitters. Upon appropriate stimulation, a rise in intracellular Ca2+ concentration triggers the fusion of vesicles with the outer membrane ...
Study of human pupillary light reflex and its potential application in autism
(University of Missouri--Columbia, 2009)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Pupillary light reflex (PLR) can be used as an objective and non-invasive method to evaluate certain brain functions. In this research, we developed ...
Development and applications of label-free optofluidic ring resonator biosensor
(University of Missouri--Columbia, 2009)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] This dissertation presents the development and applications of label-free optofluidic ring resonator (OFRR) sensor platform. The OFRR sensor naturally ...
Development of novel bionanocomposite scaffolds
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The development of three novel bionanocomposite scaffolds is presented in this dissertation. These scaffold materials are comprised of amine-functionalized ...
Regulation of calcium signaling by p130PH in astrocytes
(University of Missouri--Columbia, 2009)
Ca2+ signaling is a characteristic form of astrocyte excitability, but its role in ischemia is not clearly understood. Our previous study (Ding et al., 2009) demonstrated that astrocytes exhibit enhanced Ca2+ signaling ...
Propagation of polarized light in skeletal muscle
(University of Missouri--Columbia, 2009)
Skeletal muscle is a very important tissue in animals and humans. Optical polarization imaging is a non-invasive method to study biological tissues and provides unique polarization contrast. An imaging system was developed ...
Visible reflectance spectroscopy to observe the effect of copper embedded socks on erythema in feet
(University of Missouri--Columbia, 2008)
Objective assessment of skin characteristics is necessary to aid in the clinical detection of erythema and debilitating skin conditions. The ability to treat different skin pathologies based on individual patient skin ...
Development of electrospun synthetic bioabsorbable fibers for a novel bionanocomposite hernia repair material
(University of Missouri--Columbia, 2008)
In order to create a more durable and biocompatible hernia repair mesh, a novel bionanocomposite material based on the crosslinking of bioabsorbable polymer fibers to decellularized porcine diaphragm tissue is proposed. ...
A ratiometric fluorometer for reduced sensitivity against solvent artifacts
(University of Missouri--Columbia, 2005)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] When measuring fluorescence emission intensity, both the dye concentration and the optical absorption properties of the solvent influence the measured ...
Development of a human immunodeficiency virus (HIV-1) biosensor utilizing liquid core waveguides
(University of Missouri--Columbia, 2007)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Millions of individuals are diagnosed each year with Human Immunodeficiency Virus Type 1. Each day more individuals are receiving antiretroviral ...
Optical reflectance in fibrous tissues and skeletal muscles
(University of Missouri--Columbia, 2008)
We studied diffuse optical reflectance in two anisotropic biological tissues: high moisture soy extrudates and skeletal muscles. High moisture extrusion of soy proteins can produce healthy alternative protein sources that ...
Quantification of cell attachment on different materials as candidate electrodes for measurement of quantal exocytosis
(University of Missouri--Columbia, 2008)
A high throughput lab-on-a-chip device is being developed for single cell capture for the purpose of high time resolution quantal exocytosis measurement with high probability of cell docking. This device makes use of DLC ...
Properties of extruded white corn flour - high amylose corn starch puffs
(University of Missouri--Columbia, 2008)
This study was conducted to determine the effect of high-amylose corn starch in corn puffs on the extrusion parameters, product and textural properties and the glass transition temperature. The data was analyzed in a ...
Aptamer encoded nanopores as single molecule sensors
(University of Missouri--Columbia, 2008)
We have created a low noise, calibrated, molecular-scaled pore. The nanopore is formed either by micro-forge polishing or external penetration of the nanocavity sealed in the pipette terminal. The nanopore fabrication is ...
CPLA2: key enzyme for astroctytic cell membrane phase property change induced by abeta
(University of Missouri--Columbia, 2007)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The interaction of amyloid beta peptide (A[beta]) and cell membrane is believed to be the basis of its biological function including its toxicity to ...
Synthesis and application of semiconductor quantum dots in novel sensing applications
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] This thesis details the synthesis of CdSe/ZnS semiconductor nanocrystals (quantum dots). These quantum dots (QDs) show very interesting optical properties ...