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What's the best test for underlying osteomyelitis in patients with diabetic foot ulcers?
(Family Physicians Inquiries Network, 2015)
, evidence-based guidelines)....
A therapist survey of evidence-based practices in publicly funded youth mental health
(University of Missouri--Columbia, 2018)
sizes in controlled clinical trials for evidence-based treatments (EBTs) for youth MH problems (Weisz, Jensen-Doss & Hawley, 2006). One potential reason for this discrepancy may be that therapists within TAU contexts are not implementing EBTs. To date...
What is the best treatment for plantar fasciitis?
(Family Physicians Inquiries Network, 2003)
Mechanical therapies -- such as taping, tension night splinting, and rigid arch support -- are the most effective treatment for plantar fasciitis (strength of recommendation: A, based on randomized controlled trials). If limited or no improvement...
Should the varicella vaccine be given to all children to prevent chickenpox?
(Family Physicians Inquiries Network, 2004)
Healthy, unimmunized children who have not had varicella infection should be vaccinated (strength of recommendation: A, based on randomized controlled trials). Use of the vaccine in immunocompromised children is still being studied and has not been...
What are appropriate screening tests for infants and children?
(Family Physicians Inquiries Network, 2006)
There is adequate evidence for screening neonates for hemoglobinopathies, congenital hypothyroidism, phenylketonuria (strength of recommendation [SOR]: A), and cystic fibrosis (SOR: B). Vision screening should be done for those younger than age 5...
Do A-fib patients continue to benefit from vitamin K antagonists with advancing age?
(Family Physicians Inquiries Network, 2019)
Q Do A-fib patients continue to benefit from vitamin K antagonists with advancing age? Evidence-based answer: yes, patients with atrial fibrillation who are between the ages of 50 and 90 years continue to benefit from vitamin K antagonist therapy...
What is the best way to manage GERD symptoms in the elderly?
(Family Physicians Inquiries Network, 2006)
No evidence supports one method over another in managing uncomplicated gastroesophageal reflux disease (GERD) for patients aged >65 years. For those with endoscopically documented esophagitis, proton pump inhibitors (PPIs) relieve symptoms faster...
Does birth weight predict childhood obesity?
(Family Physicians Inquiries Network, 2008)
A birth weight greater than 4,000 g is associated with an increased risk of obesity in both childhood and adolescence (strength of recommendation [SOR]: B, systematic review and multiple cohort studies).
Q: Is event-driven PrEP dosing for HIV as effective as daily dosing?
(Family Physicians Inquiries Network, 2021-06)
Evidence based answer: PROBABLY, although there are no head-to-head trials comparing the 2 dosing regimens. Event-driven pre-exposure prophylaxis (PrEP) dosing reduces HIV conversion by 86% compared to placebo (strength of recommendation [SOR]: B...
Statin Therapy in Patients with Type 2 Diabetes
(Family Physicians Inquiries Network, 2005)
Based on current evidence, statin therapy should be offered to all patients with type 2 diabetes who are known to have coronary artery disease. [Strength of recommendation: A] For patients older than 40 years with type 2 diabetes who are not known...
How effective is spironolactone for treating resistant hypertension?
(Family Physicians Inquiries Network, 2019)
Q: How effective is spironolactone for treating resistant hypertension? EVIDENCE-BASED ANSWER: VERY EFFECTIVE. Spironolactone reduces systolic blood pressure (SPB) by 11 to 17 mm Hg and diastolic blood pressure (DPB) by up to 6 mm Hg in patients...
Improving car seat safety anticipatory guidance in the pediatric primary care setting
(University of Missouri--Columbia, 2024)
safety guidelines. The purpose and aims of the project relate to the following PICOT question: In a pediatric primary care clinic (P), how does the implementation of an evidence-based car seat safety handout at well-child visits for newborns to age 13...
Are any oral iron formulations better tolerated than ferrous sulfate?
(Family Physicians Inquiries Network, 2002)
Ferrous salt preparations (ferrous sulfate, ferrous gluconate, and ferrous fumarate) are equally tolerable. (Grade of recommendation: A, based on randomized controlled trial.) Controlled-release iron preparations cause less nausea and epigastric...
What is the evaluation and treatment strategy for Raynaud's phenomenon?
(Family Physicians Inquiries Network, 2005)
Raynaud's phenomenon is diagnosed by history,
which also plays a key role in distinguishing
primary from secondary Raynaud's phenomenon
(strength of recommendation [SOR]: C, based
on expert opinion). The initial treatment includes conservative...
Diagnosing Von Willebrand Disease
(Family Physicians Inquiries Network, 2010)
The diagnosis of vWD requires two clinical criteria: (1) a personal history, family history, or physical evidence of mucocutaneous bleeding and (2) a qualitative or quantitative decrease in functional activity of von Willebrand factor (v...
How do hyaluronic acid and corticosteroid injections compare for knee OA relief?
(Family Physicians Inquiries Network, 2017)
for symptomatic knee osteoarthritis (OA), but that insufficient evidence exists to recommend HA injections (SOR: B, evidence-based guidelines)....
What is the best strategy for monitoring the lipid-lowering effects of medical therapy used for the primary prevention of coronary artery disease (CAD)?
(Family Physicians Inquiries Network, 2001)
There is good evidence that treatment for primary prevention of CAD decreases risk of major first coronary events and cardiovascular mortality, though all-cause mortality has not been shown to be reduced. There is no evidence identifying the best...
How effectively do ACE inhibitors and ARBs prevent migraines?
(Family Physicians Inquiries Network, 2018)
Q: How effectively do ACE inhibitors and ARBs prevent migraines? Evidence-based answer: The angiotensin-converting enzyme (ACE) inhibitor lisinopril reduces the number of migraines by about 1.5 per month in patients experiencing 2 to 6 migraines...
Pharmacologic therapy for eustachian tube dysfunction
(Family Physicians Inquiries Network, 2013)
There are no medications that improve patient-oriented outcomes in children or adults with eustachian tube dysfunction. (Strength of Recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs].) Oral corticosteroids...
How often does long-term PPI therapy cause clinically significant hypomagnesemia?
(Family Physicians Inquiries Network, 2018)
Q: How often does long-term PPI therapy cause clinically significant hypomagnesemia? EVIDENCE-BASED ANSWER: Rarely. Proton pump inhibitors (PPIs) may be associated with decreases in serum magnesium laboratory values to below 1.6 to 1.8 mg...