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Now showing items 61-80 of 191
Assessing the biocompatibility of different sizes and concentrations of gold nanoparticles conjugated to decellularized tissue scaffolds
(University of Missouri--Columbia, 2016)
Gold nanoparticles conjugated to decellularized scaffolds have been studied previously within the fields of tissue engineering and biomaterials. They hold much potential for applications in soft tissue repair and improved ...
Clinical translation of nanomaterials for early detection of genetic abnormalities in fetus and retinopathy in neonates and adults
(University of Missouri--Columbia, 2017)
Nuclear medicine covers a wide variety of radionuclides to meet demands of disease. In the current study, first we have looked at the application of mono-amine mono-amide ligands for Re(V), 99mTc(V), and 186Re(V) with ...
Rapid detection and characterization of mycobacteria using microchannel electrical impedance spectroscopy
(University of Missouri--Columbia, 2017)
The presence of virulent, pathogenic bacteria in our body, food, water and other consumables is harmful and causes enormous economic and personal losses. Here we will be looking at developing a platform technology that can ...
Modeling and optimization of the Mannheimia haemolytica vaccine production process
(University of Missouri--Columbia, 2017)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Leukotoxin (Lkt) from Mannheimia haemolytica has been discovered as the primary pathogenic factor for bovine respiratory disease (BRD), causing huge ...
Integrating nanostructured artificial receptors with whispering gallery mode optical microresonators via inorganic molecular imprinting techniques
(University of Missouri--Columbia, 2016)
The creation of label-free biosensors capable of accurately detecting trace contaminants, particularly small organic molecules, is of significant interest for applications in environmental monitoring. This is achieved by ...
Natural and synthetic materials for the regeneration of osseous tissue
(University of Missouri--Columbia, 2017)
Bone is a complex tissue with many regulation mechanisms which can be taken advantage of through the release of simple signaling molecules delivered via a biodegradable material like a hydrogel. Hydrogels are water swollen ...
Cubic and spherical nanoparticles for detection and therapy of cancer
(University of Missouri--Columbia, 2016)
Cancer is the leading cause of high mortality rates. Cancer patients require advanced treatment due to lack of early prevention and diagnosis. Moreover, progression of the disease is unpredictable and personalized therapy ...
Electrospinning lecithin-polycaprolactone scaffolds with gold nanoparticles for osteoarthritis prevention
(University of Missouri--Columbia, 2018)
The human body has articular cartilage covering the ends of the bones to act as a shock absorber and aid in movement. In a disease state, this articular cartilage breaks down causing pain, swelling, and stiffness. With ...
Flourescent molecular rotors as mechanosensors in biofluids
(University of Missouri--Columbia, 2005)
Many disease states have associated blood viscosity changes. Molecular rotors, fluorescent molecules with viscosity sensitive quantum yields, have recently been investigated as a new method for biofluid viscosity measurement. ...
Logistic modeling of a biomass utilization system
(University of Missouri--Columbia, 2009)
A logistic model was developed for a biomass utilization system and implemented in ExtendSim. The model allows for system simulation and analysis of biomass supply chain in terms of economic viability and energy balance. ...
Optical stimulation of quantal exocytosis on transparent microchips
(University of Missouri--Columbia, 2007)
Photorelease of caged Ca²⁺ is a uniquely powerful tool to study the dynamics of Ca²⁺-triggered exocytosis from individual cells. Using photolithography and other microfabrication techniques, we have developed transparent ...
Detection of CD4 and CD8 t-lymphocytes and HER2 breast cancer biomarker using the opto-fluidic ring resonator biosensor
(University of Missouri--Columbia, 2009)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] We have demonstrated label-free detection of CD4+ and CD8+ T-Lymphocytes and HER2 breast cancer biomarker using the opto-fluidic ring resonator (OFRR) ...
Ratiometric techniques to determine fluid viscosity using molecular rotors
(University of Missouri--Columbia, 2007)
Molecular rotors exhibit viscosity-dependent quantum yield, potentially allowing measurements of fluid viscosity in non-mechanical manner. Several diseases are accompanied by blood plasma viscosity changes; therefore, a ...
Development of a FRET biosensor to detect the pathogen mycoplasma capricolum
(University of Missouri--Columbia, 2005)
Mycoplasmas are a species of bacteria that invade any type of cell and are adaptable to changing environments. We are developing an optical biosensor based on Fluorescence Resonance Energy Transfer (FRET) for detection of ...
Nano- and micro-scale studies of exocytosis
(University of Missouri--Columbia, 2007)
Neurons and neuroendocrine cells contain vesicles packed with hormones or neurotransmitters. Upon appropriate stimulation, a rise in intracellular Ca2+ concentration triggers the fusion of vesicles with the outer membrane ...
Detection of cold flow properties of diesel and biodiesel fuel using optical sensor
(University of Missouri--Columbia, 2006)
Identification of cloud point for biodiesel fuel can be used to optimize the performance of biodiesel fueled vehicles in cold weather. Cloud point is the temperature at which the smallest cluster of wax crystal is observed ...
Ion-selective electrodes for simultaneous real-time analysis for soil macronutrients
(University of Missouri--Columbia, 2006)
Automated sensing of soil macronutrients (i.e., N, P, and K) would allow more efficient mapping of soil nutrient variability for variable-rate nutrient management. This study reports on the development of a sensor array ...
Modeling the influence of climate and management practices on water quality in Goodwater Creek experimental watershed
(University of Missouri--Columbia, 2006)
The objective of this study was to determine relationships among weather, runoff, water quality, and best management practice (BMP) implementation in reducing atrazine losses in the 7,250-ha Goodwater Creek Experimental ...
Development of electrospun synthetic bioabsorbable fibers for a novel bionanocomposite hernia repair material
(University of Missouri--Columbia, 2008)
In order to create a more durable and biocompatible hernia repair mesh, a novel bionanocomposite material based on the crosslinking of bioabsorbable polymer fibers to decellularized porcine diaphragm tissue is proposed. ...
Polyurethane foams from novel soy-based polyols
(University of Missouri--Columbia, 2008)
Polyurethane foams and molded plastic films were prepared by reacting isocyanates with polyols containing 50% of vegetable oil-based polyols and 50% of petroleum-based polyols. The vegetable oil-based polyols included ...