Browsing School of Medicine (MU) by Title "Physiological and pharmacological characterization of the N1303K mutant CFTR"
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Physiological and pharmacological characterization of the N1303K mutant CFTR
(University of Missouri--Columbia, 2018)Background: N1303K, one of the common, severe disease-causing mutations in the CFTR gene, causes both defective biogenesis and gating abnormalities of the CFTR protein. The goals of the present study are to quantitatively ...