dc.contributor.author | Sferra, Lisa | eng |
dc.contributor.author | Kelsberg, Gary | eng |
dc.contributor.author | Dodson, Sherry | eng |
dc.date.issued | 2004 | eng |
dc.description.abstract | Angiotensin-converting enzyme (ACE) inhibitors make a significant difference for patients with diabetes as a whole. If patients both with and without microalbuminuria are included together, ACE inhibitors significantly reduce the progression of the albumin excretion rate (strength of recommendation [SOR]: A, based on multiple randomized controlled trials) and the development of overt nephropathy (SOR: A, based on 1 randomized controlled trial). However, studying diabetes without microalbuminuria separately, the effect of ACE inhibitors on progression to nephropathy does not reach statistical significance. This applies to both type 1 and 2 diabetes (SOR: A, based on randomized controlled trials with heterogenous results). Results are contradictory regarding whether ACE inhibition delays new onset of diabetic microalbuminuria. | eng |
dc.identifier.uri | http://hdl.handle.net/10355/3022 | eng |
dc.language | English | eng |
dc.publisher | Family Physicians Inquiries Network | eng |
dc.relation.ispartofcollection | Clinical Inquiries, 2004 (MU) | eng |
dc.relation.ispartofcommunity | University of Missouri--Columbia. School of Medicine. Department of Family and Community Medicine. Family Physicians Inquiries Network | eng |
dc.relation.ispartofseries | Journal of family practice, 53, no. 01 (January 2004): 68-69. | eng |
dc.rights | OpenAccess. | eng |
dc.rights.license | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License. | eng |
dc.subject | cardiovascular risk factor | eng |
dc.subject | albumin excretion rate | eng |
dc.subject | microalbuminuria | eng |
dc.subject.lcsh | Non-insulin-dependent diabetes | eng |
dc.subject.lcsh | Diabetic Nephropathies -- Treatment | eng |
dc.subject.lcsh | Albuminuria | eng |
dc.subject.lcsh | Coronary heart disease -- Risk factors | eng |
dc.subject.lcsh | Angiotensin-Converting Enzyme Inhibitors | eng |
dc.title | Do ACE inhibitors prevent nephropathy in type 2 diabetes without proteinuria? | eng |
dc.type | Article | eng |