Browsing 2007 Dissertations (MU) by Thesis Advisor "Gillis, Kevin D."
Now showing items 1-3 of 3
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Identifying the importance of phosphorylation of SNAP-25 at Ser187 in protein kinase C-mediated enhancement of exocytosis
(University of Missouri--Columbia, 2007)Protein Kinase C (PKC) activation has been shown to enhance exocytosis in various studies. However, the molecular mechanism for PKC to promote exocytosis is still elusive. A possible target of PKC is SNAP-25 (25 kDa ... -
Nano- and micro-scale studies of exocytosis
(University of Missouri--Columbia, 2007)Neurons and neuroendocrine cells contain vesicles packed with hormones or neurotransmitters. Upon appropriate stimulation, a rise in intracellular Ca2+ concentration triggers the fusion of vesicles with the outer membrane ... -
Optical stimulation of quantal exocytosis on transparent microchips
(University of Missouri--Columbia, 2007)Photorelease of caged Ca²⁺ is a uniquely powerful tool to study the dynamics of Ca²⁺-triggered exocytosis from individual cells. Using photolithography and other microfabrication techniques, we have developed transparent ...