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Now showing items 81-100 of 178
Pupillary light reflex in children with autism spectrum disorders
(University of Missouri--Columbia, 2013)
Pupillary light reflex (PLR) refers to the phenomenon of pupil size changing with respect to retinal illumination. It's a noninvasive, functional test which can reveal a rich set of information about nervous system. Abnormal ...
Nanoparticle mediated ablation of breast cancer cells using a nanosecond pulsed electric field
(University of Missouri--Columbia, 2013)
In the past, both nanomaterials and various heating modalities have been researched as means for treating cancers. However, many of the current methodologies have the flaws of inconsistent tumor ablation and significant ...
Electromagnetic stimulation of a composite scaffold for wound healing
(University of Missouri--Columbia, 2012)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Decellularized tissues have been investigated as natural sources for tissue scaffolds as synthetic mimicry of the natural extracellular matrix is quite ...
Photoacoustic detection of circulating tumor cells
(University of Missouri--Columbia, 2013)
Photoacoustics is one of the new branches in biomedical diagnostics that holds lot of new promises and advancements. It is a unique field that deals with the conversion of photons into ultrasound waves. It is only in the ...
The role of astrocytic calcium signaling in brain damage after photothrombosis
(University of Missouri--Columbia, 2011)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Ischemic stroke is the third leading cause of death in industrialized countries. Our previous study found elevated [Ca[superscript 2+]]i signals in ...
Regulation of L-type calcium channel sparklet activity by PKC and C-src
(University of Missouri--Columbia, 2010)
Ca2+ sparklets are elementary fluorescence events associated with Ca2+ entry through L-type Ca2+ channels (Cav1.2) channels and are classified as persistent and low activity Ca2+ sparklets. Persistent Ca2+ sparklets are ...
A modeling approach to ultrasound evaluation of material properties
(University of Missouri--Columbia, 2010)
A method for estimating the mechanical properties of a viscoelastic sample from ultrasound measurements was developed. The sample was represented as a mechanical network according to the Kelvin-Voigt model and linear ...
True depth resolved polarization sensitive optical coherence tomography
(University of Missouri--Columbia, 2012)
Polarization sensitive optical coherence tomography (PSOCT) can image sample polarization properties including retardance, diattenuance, and optical axis and has potential applications in many biomedical fields. However, ...
H₂O₂-mediated RAGE up-regulation on A[beta]-induced superoxide in cerebral endothelial cells
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The up-regulation of receptor for advanced glycation (RAGE) product has been implicated in the pathophysiology of Alzheimer's disease (AD). Elevated ...
Properties of extruded snacks containing tomato and garlic
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Tomato and garlic may provide health benefits due to their bioactive compounds and fibers. The main objective of this study was to investigate the ...
Development of novel bionanocomposite scaffolds
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The development of three novel bionanocomposite scaffolds is presented in this dissertation. These scaffold materials are comprised of amine-functionalized ...
Development of a biosensor for the detection of Helicobacter hepaticus utilizing multi-functioning immobilization platforms
(University of Missouri--Columbia, 2010)
Optical biosensor development is a process involving the careful selection of the material for the immobilization platform, design of the detection mechanism and integration with optical and electronic equipment. The ability ...
Development and applications of label-free optofluidic ring resonator biosensor
(University of Missouri--Columbia, 2009)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] This dissertation presents the development and applications of label-free optofluidic ring resonator (OFRR) sensor platform. The OFRR sensor naturally ...
Functional study of Kcv potassium channel through manipultion [sic] of individual subunits
(University of Missouri--Columbia, 2010)
Potassium channels make up a ubiquitous, physiologically essential class of integral membrane proteins. Many K+ channels contain four identical symmetrically associated subunits. To explore the role of an individual subunit ...
Molecularly imprinted polymer labeled with quantum dots for detection of nitroaromatic explosives
(University of Missouri--Columbia, 2010)
A sensing device for explosive compounds is a fundamental step towards the capability to detect the presence of landmines, improvised explosive devices (IEDs), and other unexploded ordinance. To detect high explosive ...
Applications of the opto-fluidic ring resonator for DNA methylation analysis and microfluidic laser development
(University of Missouri--Columbia, 2010)
For several decades, optical ring resonators have played an important role in the field of telecommunications. Within only the past decade however, ring resonators have been applied for the purposes of biological and ...
Development of land-use map for Salt River basin using satellite imagery
(University of Missouri--Columbia, 2010)
The Salt River Basin in northeastern Missouri is the major water supply source for people in the region. There is a need to build a long term simulation and to validate the long term trend of pollutant concentrations in ...
Modeling of delayed fluorescence from photosystem II and applications in assessment of drought and chemical stresses
(University of Missouri--Columbia, 2009)
Photosynthesis is not only vital for plant growth and survival but also indicative of plant-environment interactions. This research was designed to analyze photoelectron kinetics and its dependence on environmental factors. ...
Development of a fluorescence-based protease biosensor using nanoscale platforms
(University of Missouri--Columbia, 2010)
The development of a protease biosensor utilizing nanomaterials is presented in this dissertation. Peptide substrates and nanomaterial platforms were investigated to increase the sensitivity and response time for the ...
Switchgrass production in the central claypan region of Missouri
(University of Missouri--Columbia, 2010)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Severe soil erosion across the Central Claypan Region of Missouri has been correlated with low productivity as the depth to the claypan horizon ...