Search
Now showing items 1-20 of 78
Generation, collection and characterization of nanoparticles and their diffusion in arbitrary tumor and normal tissue geometry
(University of Missouri--Columbia, 2010)
distribution of these nanoparticles using a Scanning Mobility Particle Spectrometer. We designed a nanoparticle collection cell to collect the nanoparticles efficiently, analyzed the nanoparticles for shape and size using Tunneling Electron Microscopy (TEM...
Identification and characterization of M cells in the mammalian conjunctiva
(University of Missouri--Columbia, 2007)
the hypothesis that the Guinea pig conjunctival FAE contains an antigen-sampling M cell. A cell with typical M-cell characteristics was identified in the conjunctival FAE using a variety of microscopy techniques. These putative M cells selectively bound...
Development of a flexible image-based approach for studying signal transduction in isolated arterioles
(University of Missouri--Columbia, 2007)
Myogenic constriction in arterioles occurs when membrane tension leads to smooth muscle depolarization and voltage-gated calcium channel activation. A barrier to understanding the exact signaling events is the limited ...
Large-scale fabrication of SiC nanofibers and plasma interface engineering of polymer nanocomposites and dental composite restoration
(University of Missouri--Columbia, 2010)
was attributed to enhanced dispersion and interfacial adhesion observed visually and by electron microscopy. A non-thermal argon plasma brush treatment increased the micro-tensile strength of dental composite restorations. FTIR observed an increase in carbonyl...
Gas sorption in engineered carbon nanospaces
(University of Missouri--Columbia, 2009)
. Characterizations include surface areas and pore-size distributions from nitrogen adsorption at 77 K; pore-size distribution from methane adsorption at 293 K; scanning and transmission electron microscopy; and chemical composition analysis. In two case studies...
Examination of specific amino acid residues of desulfovibrio desulfuricans cytochrome C₃ in electron transfer
(University of Missouri--Columbia, 2005)
Sulfate-reducing bacteria (SRB) are strictly anaerobic microorganisms present throughout the environment. These microorganisms are able to utilize a variety of electron donors and couple the oxidation of those compounds to the reduction of sulfate...
The effects of temperature and admixture handling on lipid emulsion stability in centrally administered veterinary parenteral nutrition (PN) admixtures
(University of Missouri--Columbia, 2008)
focused on the duration that the lipid component of these admixtures can be administered safely to a patient. To that end, this project involved examining and measuring the diameter of lipid particles using transmission electron microscopy to determine...
Fabrication and characterization of polymer based metal-oxide-semiconductor and non-volatile memory devices
(University of Missouri--Columbia, 2009)
Organic field-effect transistors (FETs) have been widely investigated due to their potential applications in low cost, large area, and flexible electronics. Despite the rapid progress in organic FETs there are still obstacles such as high density...
Viral envelope proteins and the HIV-1 accessory gene Vpu mediate selectivity of viral and host proteins in retroviral assembly
(University of Missouri--Columbia, 2012)
enigmatic and there are no anti-retroviral drugs that target the assembly stage of HIV replication. Much of the knowledge we have garnered on retrovirus assembly has been through a process known as pseudotyping, where the core structural proteins will accept...
Effect of silver nanoparticles on planktonic and biofilm cell growth
(University of Missouri--Columbia, 2009)
Silver nanoparticles (Ag NPs) are one of the most widely used nanoparticles, most notably serving as an antimicrobial agent for sanitization and medical purposes. Despite of their widespread use, little was known about the ...
An exploration of chemical agents detection using the quantum fingerprint [superscript TM] technology
(University of Missouri--Columbia, 2009)
The detection of chemical agents using a novel, gas-phase, sensor technology has been examined experimentally in this work. The goal of the work was to determine the feasibility of using solid-state materials as gas-phase ...
Activation of astrocytes: involvement of NADPH oxidase and cytosolic phospholipase A2
(University of Missouri--Columbia, 2007)
pathways and cPLA2 in astrocytes. We further demonstrated that excess production of ROS, such as that mediated by menadione, can alter cell membrane properties, morphology, and cytoskeletal arrangement and in turn cell death mechanism.--From public.pdf...
Effects of oxidative stress and Alzheimer's amyloid-beta peptide on astrocytes
(University of Missouri--Columbia, 2006)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Oxidative stress and deposition of amyloid-[beta] peptide (A[beta]) in brains have been hypothesized as causes of Alzheimer's disease (AD), and research ...
Biogeochemistry and inorganic geochemistry as indicators of the paleoenvironment and paleohydrology of the Al-Azraq Basin, Jordan
(2013)
This study investigates the biogeochemical and inorganic geochemical
indicators for past environments and paleohydrology of a high resolution sediment record
from the Al-Azraq Basin, Jordan. The second largest basin in ...
Development of a biosensor for the detection of Helicobacter hepaticus utilizing multi-functioning immobilization platforms
(University of Missouri--Columbia, 2010)
Optical biosensor development is a process involving the careful selection of the material for the immobilization platform, design of the detection mechanism and integration with optical and electronic equipment. The ability of biosensor...
Synthesis and application of semiconductor quantum dots in novel sensing applications
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] This thesis details the synthesis of CdSe/ZnS semiconductor nanocrystals (quantum dots). These quantum dots (QDs) show very interesting optical properties ...
Frequency domain fluorescent molecular tomography and molecular probes for small animal imaging
(University of Missouri--Columbia, 2009)
In this thesis, we have developed a frequency domain fluorescent molecular tomographic system based on the heterodyne technique using a single source and detector pair for small animal imaging. In our system, the intensity ...
Caveolin-1 A scaffold for microcompartmental organization of membrane-associated glycolysis
(University of Missouri--Columbia, 2007)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The role of membrane caveolae in the compartmentation of membrane glycolytic metabolism indicates a pivotal role of caveolin in the localization of ...
Physical mechanisms of cell rearrangements: from tissue liquidity to artificial organ structures
(University of Missouri--Columbia, 2006)
This research presents a study of biological self-assembly in which we create 3D living functional tissue structures by exploiting the self organizing capacity of cells and tissues. Tissues composed of adhesive and motile ...
Chloroplast GFP expression in tobacco plants agroinfiltrated with tobacco mosaic virus based vectors
(University of Missouri--Columbia, 2009)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Viruses are submicroscopic infectious particles comprising of nucleic acid and protein which can replicate only within living host cells. TMV is a ...