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Activated protein C resistance in Behcet's disease
(2013-09-02)
Abstract
Behcet’s disease is a chronic multi-system disorder of unknown etiology with protean manifestations. Venous thromboembolism is more common than arterial thrombosis, with deep vein thrombosis being the ...
Prehospital intravenous access and fluid resuscitation in severe sepsis: an observational cohort study
(2014-09-27)
Abstract
Introduction
Prompt treatment of severe sepsis in the Emergency Department reduces deaths, but the role of prehospital ...
Meeting report: 2nd workshop of the United States culture collection network (May 19-21, 2014, State College, PA, USA)
(2014-12-29)
This report summarizes the activities and outcomes of the second workshop of the US Culture Collection Network, formally an activity of the US National Science Foundation sponsored Research Coordination Network for a ...
Recurrent acute pancreatitis and massive hemorrhagic ascites secondary to a duodenal duplication in a child: a case report
(2013-03-14)
Abstract
Introduction
Duodenal duplication is a rare congenital malformation and has been reported as a rare cause of recurrent acute pancreatitis. Hemorrhagic ascites has been reported in only ...
Evaluation of a new fluorescence quantitative PCR test for diagnosing Helicobacter pylori infection in children
(2013-01-14)
Abstract
Background
Numerous diagnostic tests are available to detect Helicobactor pylori (H. pylori). There has been no single test available to detect H. pylori infection reliably. We evaluated ...
Computational analysis and predictive modeling of polymorph descriptors
(2013-02-04)
Abstract
Background
A computation approach based on integrating high throughput binding affinity comparison and binding descriptor classifications was utilized to establish the ...
An embedded multichannel telemetry unit for bone strain monitoring
(2013-10-17)
Abstract
An embedded telemetry unit for bone strain monitoring is presented. The telemetry unit is designed using commercially available components to lower design time and manufacturing ...
Human immunodeficiency virus type 1 viral protein R (Vpr) induces CCL5 expression in astrocytes via PI3K and MAPK signaling pathways
(2013-11-13)
Abstract
Background
Neurocognitive impairments remain prevalent in HIV-1 infected individuals despite current antiretroviral therapies. It is increasingly becoming evident that astrocytes ...
Regional pulse wave velocities and their cardiovascular risk factors among healthy middle-aged men: a cross-sectional population-based study
(2014-01-13)
Abstract
Background
Both carotid-femoral (cf) pulse wave velocity (PWV) and brachial-ankle (ba) PWV employ arterial sites that are not consistent with the path of blood flow. Few previous ...
Suppression of nitric oxide induction and pro-inflammatory cytokines by novel proteasome inhibitors in various experimental models
(2011-10-12)
Abstract
Background
Inflammation has been implicated in a variety of diseases associated with ageing, including cancer, cardiovascular, and neurologic diseases. We have recently established that the proteasome ...
Insights into the pathogenesis of axial spondyloarthropathy from network and pathway analysis
(2012-07-16)
Abstract
Background
Complex chronic diseases are usually not caused by changes in a single causal gene but by an unbalanced regulating ...
Association of 25-hydroxyvitamin D deficiency with NT-pro BNP levels in patients with acute myocardial infarction: a cross-sectional analysis
(2011-12-15)
Abstract
Background
Nutritional vitamin D deficiency is an emerging risk factor for acute myocardial infarction (AMI) and heart failure. The association of 25-hydroxyvitamin D levels with N-terminal pro B-type natriuretic ...
Encapsulation of docetaxel in oily core polyester nanocapsule intended for breast cancer therapy
(2011-12-14)
Abstract
This study is designed to test the hypothesis that docetaxel [Doc] containing oily core nanocapsules [NCs] could be successfully prepared with a high percentage encapsulation efficiency [EE%] and high drug loading. ...
Inhibition of nitric oxide in LPS-stimulated macrophages of young and senescent mice by delta-tocotrienol and quercetin.
(2011-12-20)
Abstract
Background
Changes in immune function believed to contribute to a variety of age-related diseases have been associated with increased production of nitric oxide (NO). We have recently reported that ...
Comparative genome sequence analysis underscores mycoparasitism as the ancestral life style of Trichoderma
(2011-04-18)
Abstract
Background
Mycoparasitism, a lifestyle where one fungus is parasitic on another fungus, has special relevance when the prey is a plant pathogen, providing a strategy for biological control of pests for plant ...
TILLING to detect induced mutations in soybean
(2008-01-24)
Abstract
Background
Soybean (Glycine max L. Merr.) is an important nitrogen-fixing crop that provides much of the world's protein ...
Design, baseline characteristics, and retention of African American light smokers into a randomized trial involving biological data
(2011-01-25)
Abstract
Background
African Americans experience significant tobacco-related health disparities despite the fact that over half of African American smokers are light smokers (use ≤10 cigarettes per day). African ...
A Bayesian Analysis for Identifying DNA Copy Number Variations Using a Compound Poisson Process
(2010-08-17)
To study chromosomal aberrations that may lead to cancer formation or genetic diseases, the array-based Comparative Genomic Hybridization (aCGH) technique is often used for detecting DNA copy number variants (CNVs). Various ...
Gene selection for classification of microarray data based on the Bayes error
(2007-10-03)
Abstract
Background
With DNA microarray data, selecting a compact subset of discriminative genes from thousands of genes is a ...
Effect of stroke location on the laryngeal cough reflex and pneumonia risk
(2005-08-04)
Abstract
Background
The purpose of this study was to evaluate the risk of developing pneumonia in acute stroke patients comparing ...