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Now showing items 61-80 of 414
Sleep apnea in adults: How accurate is clinical prediction?
(Family Physicians Inquiries Network, 2009)
Questionnaires, physical examination, and clinical prediction rules estimate the pretest probability of obstructive sleep apnea hypopnea syndrome (OSAHS), but are not specific enough to make the diagnosis (strength of ...
Management of Cervical Lymphadenitis in Children
(Family Physicians Inquiries Network, 2008)
for spontaneous resolution over four to six weeks. (Strength of Recommendation [SOR]: C, based on expert opinion)....
Do imaging studies aid diagnosis of acute sinusitis?
(Family Physicians Inquiries Network, 2003)
Accurate diagnosis of acute sinusitis in both children and adults depends on the history and clinical examination of the patient. While the clinical signs and symptoms of acute sinusitis are often difficult to distinguish ...
What is the best treatment for oral thrush in healthy infants?
(Family Physicians Inquiries Network, 2008)
Nystatin oral suspension is a safe first-line therapy; fluconazole is more effective (strength of recommendation [SOR ]: B, 1 small randomized controlled trial [RCT]) but has not been approved by the Food and Drug ...
Which drugs are most effective for moderate to severe depression in adolescents?
(Family Physicians Inquiries Network, 2008)
with placebo in trials lasting up to 12 weeks (strength of recommendation [SOR]: A, meta-analysis). Fluoxetine combined with cognitive behavioral therapy (CBT) is superior to fluoxetine alone, CBT alone, or placebo (SOR: B, single well-done randomized...
What's the most effective treatment for giardiasis?
(Family Physicians Inquiries Network, 2008)
A single 2-g dose of tinidazole is the best treatment (strength of recommendation [SOR]: A, based on meta-analysis). Other drugs, such as nitazoxanide, metronidazole, mebendazole, and albendazole, can also be used (SOR: A, based on randomized...
What is the best test for peripheral vascular disease?
(Family Physicians Inquiries Network, 2008)
An ankle-brachial index is best for evaluating patients with symptoms of claudication (strength of recommendation [SOR]: B, multiple cohort studies). That said, duplex ultrasonography or magnetic resonance angiography may ...
What is the best treatment for infants with colic?
(Family Physicians Inquiries Network, 2006)
Infantile colic, defined as excessive crying in an otherwise healthy baby, is a distressing phenomenon, but there is little evidence to support the many treatments offered. Several small studies report some benefit from use of a hypoallergenic...
Should you test or treat pregnant women with a history of pregnancy-related VTE?
(Family Physicians Inquiries Network, 2013)
No high-quality evidence supports testing for thrombophilia in pregnant patients who have experienced venous thromboembolism (VTE) in a previous pregnancy. Antepartum and postpartum anticoagulation with LMWH produces lower rates of VTE in patients...
What Is the Best Antiviral Agent for Influenza Infection?
(Family Physicians Inquiries Network, 2004)
compared the effectiveness of these agents, and no direct evidence exists regarding their relative efficacy. In the absence of specific contraindications, amantadine and rimantadine are preferred for use in most patients because these two agents cost less...
Do glucosamine or chondroitin cause regeneration of cartilage in osteoarthritis?
(Family Physicians Inquiries Network, 2003)
No direct evidence suggests glucosamine or chrondroitin cause regeneration of cartilage in osteoarthritis. Use of glucosamine sulfate in knee osteoarthritis prevents joint space narrowing on radiographs (strength of recommendation [SOR]: B, based...
Which smoking cessation interventions work best?
(Family Physicians Inquiries Network, 2011)
Nicotine replacement therapy (NRT), bupropion, nortriptyline, clonidine, and varenicline are all effective, although insufficient evidence exists to recommend one intervention over another (SOR: A, systematic reviews). Effective nonpharmacologic...
When should you admit a patient with suspected CAP?
(Family Physicians Inquiries Network, 2008)
of recommendation [SOR]: B, based on 3 prospective cohort studies). Alternatively, consider hospitalization for patients presenting with a Pneumonia Severity Index (PSI) class of 4 or 5 (SOR: B; 1 prospective cohort study). There are no studies that test whether...
The shrinking case for saw palmetto
(Family Physicians Inquiries Network, 2012)
Advise men with benign prostatic hyperplasia (BPH) not to take saw palmetto for urinary symptoms. Explain that it has not been found to alleviate symptoms, even at triple the standard dose. Stength of recommendation: A: Based on evidence from a high...
What are the most effective nonpharmacologic therapies for irritable bowel syndrome?
(Family Physicians Inquiries Network, 2008)
Herbal formulations, certain probiotics, elimination diets based on immunoglobulin G (IgG) antibodies, cognitive behavioral therapy, and self-help books have been shown to decrease global symptoms of irritable bowel syndrome (IBS) and improve...
What's the best way to relieve mastitis in breastfeeding mothers?
(Family Physicians Inquiries Network, 2011)
for treating undifferentiated mastitis is unknown (SOR: A, 1 systematic review). Consider prescribing antibiotics for women whose mastitis symptoms don't improve after 12 to 24 hours of frequent breast emptying (SOR: C, consensus guideline)....
Do patients with type 2 diabetes who aren't taking insulin benefit from self-monitoring blood glucose?
(Family Physicians Inquiries Network, 2013)
Patients with type 2 diabetes who aren't on insulin and perform self-monitoring of blood glucose (SMBG) show small but significant reductions in hemoglobin A1c (HbA1c) at 6 months but not at 12 months (strength of recommendation [SOR]: B, systematic...
What predicts a successful smoking cessation attempt?
(Family Physicians Inquiries Network, 2006)
Quit date abstinence (strength of recommendation [SOR]: B, based on low-quality randomized controlled trial [RCT] of healthy subjects) and refraining from tobacco products within the first 2 weeks after an attempt (SOR: A, based on 2 RCTs) predict...
What is the most effective treatment for acute low back pain?
(Family Physicians Inquiries Network, 2002)
Nonsteroidal anti-inflammatory drugs (NSAIDs) are more effective than placebo for pain relief in patients with acute low back pain (grade of recommendation: A). There is no consistent evidence that NSAIDs are more effective than acetaminophen (grade...
Medications for Insomnia Treatment in Children
(Family Physicians Inquiries Network, 2008)
Melatonin may be effective for treating insomnia in healthy children and in those with physical or learning disabilities (Strength of Recommendation [SOR]: B). Short-term use of melatonin is safe in children, but there is insufficient evidence...