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Recent Submissions

  • Which treatments for persistent otitis media with effusion are beneficial? 

    Satre, Thomas J.; Nashelsky, Joan (Family Physicians Inquiries Network, 2005-02)
    Treatments such as antibiotics, steroids, antihistamines/decongestants, and mucolytics afford no long-term benefit in the treatment of patients with otitis media with effusion (OME). [Strength of recommendation: A] Surgical ...
  • Treatment of Calf Deep Venous Thrombosis 

    Rotert, Eric M.; Basarich, John R.; Nashelsky, Joan (Family Physicians Inquiries Network, 2005-06)
    Patients with a first episode of calf DVT with a transient risk factor should receive heparin therapy followed by oral anti- coagulation for six to 12 weeks. [Strength of recommendation: A, based on systematic review of ...
  • Treatment of Early Parkinson's Disease 

    Dickerson, Lori M.; Young, Sara E.; Simpson, William M.; Nashelsky, Joan (Family Physicians Inquiries Network, 2005-08)
    Treatment of early Parkinson's disease with either selegiline (Eldepryl), a dopamine agonist (pramipexole [Mirapex], ropinirole [Requip], or bromocriptine [Parlodel]), or the combination of levodopa and carbidopa (Sinemet) ...
  • St. John's Wort for Depression 

    Malaty, Wail (Family Physicians Inquiries Network, 2005-04)
    St. John's wort is safe and effective for short-term (six to eight weeks) relief of mild to moderate depression in adults. [Strength of recommendation: A, based on consistent evidence from high-quality systematic reviews]
  • Raloxifene for Prevention of Osteoporotic Fractures 

    Diehr, Sabina; Mijal, Sara; Nashelsky, Joan (Family Physicians Inquiries Network, 2005-07)
    Raloxifene (60 mg daily for three years) will prevent one vertebral fracture, including asymptomatic fractures, for every 46 postmenopausal women with osteoporosis or presence of previous vertebral fractures. Raloxifene ...
  • Antiviral Agents for Pregnant Women with Genital Herpes 

    Wenner, Christopher; Nashelsky, Joan (Family Physicians Inquiries Network, 2005-11)
    There is no evidence that the use of antiviral agents in women who are pregnant and have a history of genital herpes prevents perinatal transmission of herpes simplex virus (HSV) to neonates. [Strength of recommendation: ...
  • Colorectal Cancer Screening 

    Gaskie, Sean (Family Physicians Inquiries Network, 2005-03)
    Both fecal occult blood testing (FOBT) and flexible sigmoidoscopy are effective in screening for colorectal cancer. FOBT can reduce mortality from colorectal cancer. [Strength of recommendation: A, based on high-quality ...
  • Statin Therapy in Patients with Type 2 Diabetes 

    Lo, Vincent; Noviasky, John; Nashelsky, Joan (Family Physicians Inquiries Network, 2005-09)
    Based on current evidence, statin therapy should be offered to all patients with type 2 diabetes who are known to have coronary artery disease. [Strength of recommendation: A] For patients older than 40 years with type 2 ...
  • Combined Oral Contraceptives for Mothers Who Are Breastfeeding 

    Guthmann, Richard A.; Bang, Jane; Nashelsky, Joan (Family Physicians Inquiries Network, 2005-10)
    There is currently no evidence of harm; however, few patients have been studied and existing studies have many limitations. Therefore, it is not possible to definitively answer this question at this time. The existing ...
  • Intravenous Fluids for Children with Gastroenteritis 

    Banks, J. Burton (Jerry Burton), 1963-; Meadows, Susan E. (Family Physicians Inquiries Network, 2005-01)
    Most children with gastroenteritis do not require intravenous fluids and will respond favorably to ORT. Intravenous fluids do not shorten the duration of gastroenteritis and are more likely to cause adverse effects than ...
  • Counseling or Antidepressants for Treating Depression? 

    Spencer, Donald C.; Nashelsky, Joan (Family Physicians Inquiries Network, 2005-12)
    Both antidepressant medications and psychologic treatment are beneficial for adult patients with mild to moderate depression, with no consistent evidence that one type of treatment is more effective than the other. [Strength ...
  • Management of Subclinical Hypothyroidism 

    Ibay, Annamarie D.; Bascelli, Lynda M.; Nashelsky, Joan (Family Physicians Inquiries Network, 2005-05)
    Treatment of subclinical hypothyroidism with levothyroxine may be of most benefit to patients with symptoms suggestive of hypothyroidism and those patients with thyroid-stimulating hormone (TSH) levels higher than 10 μIU ...
  • Who should get hepatitis A vaccination? 

    Brown, Rhett; Cable, Kathy (Family Physicians Inquiries Network, 2005-07)
    The following groups are at increased risk of contracting or having severe outcomes from hepatitis A and should receive vaccination. • Persons traveling to or working in countries that have high or intermediate rates ...
  • Which late-stage Alzheimer's patients should be referred for hospice care? 

    Modi, Seema; Moore, Cassandra (Family Physicians Inquiries Network, 2005-11)
    Medicare guidelines are used to determine eligibility for hospice care (strength of recommendation [SOR]: C, based on expert opinion), but they correlate with 6-month mortality no better than an experienced clinician's ...
  • When should a chest x-ray be used to evaluate acute-onset productive cough for adults? 

    Pisarik, Paul; Montoya, Cathy C. (Family Physicians Inquiries Network, 2005-12)
    Even though the most common reason to order a chest x-ray in the evaluation of an acute-onset, productive cough is to rule out pneumonia, there is no strong evidence to help a physician decide when to order this chest ...
  • When should you order a Lyme titer? 

    Kulie, Teresa; Vogt, Kevin; Sevetson, Erika (Family Physicians Inquiries Network, 2005-12)
    Lyme titers should be ordered for patients with signs or symptoms of disseminated Lyme disease, but who do not have the pathognomonic erythema migrans rash (strength of recommendation [SOR]: C, based on expert opinion). ...
  • When is neuroimaging warranted for headache? 

    Grayson, Sharon; Neher, Jon O.; Howard, Ellen (Family Physicians Inquiries Network, 2005-11)
    Neuroimaging is warranted to evaluate headaches when patients present to an emergency department with signs or symptoms of an intracranial lesion. These signs or symptoms include abrupt onset of headache, focal neurological ...
  • What is the best way to identify patients with white-coat hypertension? 

    Fisher, Michael; Blackwell, Jean (Family Physicians Inquiries Network, 2005-06)
    Ambulatory blood pressure monitoring is currently the gold standard for detecting patients with white-coat hypertension. Women and all patients with lower office systolic blood pressures, stage I hypertension, and no target ...
  • What vitamins and minerals should be given to breastfed and bottle-fed infants? 

    Eglash, Anne; Kendall, Susan K. (Family Physicians Inquiries Network, 2005-12)
    Breastfed and formula-fed infants should receive intramuscular vitamin K soon after birth to prevent classic hemorrhagic disease of the newborn (strength of recommendation [SOR]: A, systematic review of controlled trials). ...
  • What treatments prevent miscarriage after recurrent pregnancy loss? 

    Price, Matt; Kelsberg, Gary; Safranek, Sarah (Family Physicians Inquiries Network, 2005-10)
    Progesterone produces a small but significant decrease in miscarriage among pregnant women with 3 or more unexplained pregnancy losses (strength of recommendation [SOR]: A, based on a meta-analysis of 3 small randomized ...

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