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Recent Submissions

  • Aspirin Use in Children for Fever or Viral Syndromes 

    Beutler, Anthony I.; Chesnut, Gregory T.; Mattingly, John C.; Jamieson, Barbara (Family Physicians Inquiries Network, 2009-12)
    Aspirin should not be used to treat acute febrile viral illness in children. (Strength of Recommendation [SOR]: C, based on case- control studies). Although no causal link has been proven, data from case-control and historic ...
  • Do intercontraction intervals predict when a woman at term should seek evaluation of labor? 

    Mull, Courtney; McPherson, Vanessa; Zolotor, Adam J.; Kaufmann, Leonora (Family Physicians Inquiries Network, 2009-12)
    A reduction in the intercontraction interval is associated with active labor (strength of recommendation [SOR]: B, cohort study). Most primigravidas who have had regular contractions for 2 hours and multigravidas who have ...
  • What does the evidence tell us about treating very-high-risk patients to an LDL <70 mg/dL? 

    Nelson, Carrie; Hitchcock, Kristin; Bohlen, James A. (Family Physicians Inquiries Network, 2009-12)
    No studies directly compare low-density lipoprotein (LDL) levels <70 mg/dL to levels of 71 to 100 mg/dL in very-high-risk patients. However, no evidence suggests a “floor” for LDL cholesterol levels beyond which further ...
  • What's the best way to monitor low-risk patients with a history of differentiated thyroid cancer? 

    Albrecht, Angela M.; Paulson, Christopher P.; Kovach, Fran E. (Family Physicians Inquiries Network, 2009-12)
    Recombinant human thyrotropin (rhTSH)-stimulated serum thyroglobulin (Tg) level alone is sufficient to monitor for recurrent disease in low-risk patients with a history of differentiated thyroid cancer (DTC) (strength ...
  • Which strategies work best to prevent obesity in adults? 

    Boltri, John M.; House, Alice A.; Nelson, Roxanne M. (Family Physicians Inquiries Network, 2009-12)
    Regular physical activity decreases long-term weight gain (strength of recommendation [SOR]: B, 2 high-quality, randomized controlled trials [RCTs]). Decreasing fat intake (SOR: B, 1 high-quality systematic review) and ...
  • Aspirin in Patients with Acute Ischemic Stroke 

    Park, Michael K.; Smith, Peter C.; Wanserski, Gerri R. (Family Physicians Inquiries Network, 2009-02)
    Aspirin in a daily dose of 160 to 300 mg initiated within 48 hours of symptom onset results in a net decrease in morbidity and mortality caused by acute ischemic stroke (Strength of Recommendation [SOR]: A, based on a ...
  • Treatment for Anogenital Molluscum Contagiosum 

    Brown, Michelle R.; Paulson, Christopher P.; Henry, Susan L. (Family Physicians Inquiries Network, 2009-11)
    There is no evidence from comparative trials to suggest a single best treatment method for anogenital molluscum contagiosum. Randomized controlled trials suggest self-administered topical imiquimod or podophyllotoxin cream ...
  • When should you consider implanted nerve stimulators for lower back pain? 

    Merok, Joshua R.; Guthmann, Richard A.; Blevins, Amy (Family Physicians Inquiries Network, 2009-11)
    Patients can gain more pain relief from spinal cord stimulation (SCS) than from reoperation (strength of recommendation [SOR]: A, 2 randomized controlled trials [RCTs]). SCS can also treat chronic low back pain effectively ...
  • Which asthma patients should get the pneumococcal vaccine? 

    Harris, John Brock; Edgerton, Lisa; Stafford, Karen (Family Physicians Inquiries Network, 2009-11)
    Adults between the ages of 19 and 64 years who have chronic lung disease, including asthma, should get the vaccine, as should all patients 65 years and older (strength of recommendation [SOR]: C, consensus guide-lines). ...
  • Which interventions are best for alleviating nipple pain in nursing mothers? 

    Lochner, Jennifer E.; Livingston, Catherine J.; Judkins, Dolores Zegar (Family Physicians Inquiries Network, 2009-11)
    The best intervention is education on proper positioning and attachment of the infant (strength of recommendation [SOR]: A, a systematic review of randomized controlled trials [RCTs]). No single topical preparation has ...
  • When should you suspect community-acquired MRSA? How should you treat it? 

    May, Todd J.; Safranek, Sarah (Family Physicians Inquiries Network, 2009-05)
    There are no clinical or epidemiologic features that will help you to clearly distinguish community-acquired methicillin-resistant Staphylococcus aureus infections (CA-MRSA) from methicillin-sensitive (CA-MSSA) infections ...
  • When is it OK for children to start drinking fruit juice? 

    Stephens, Mark B.; Keville, Meaghan P.; Hathaway, Nathanael E.; Kendall, Susan K. (Family Physicians Inquiries Network, 2009-09)
    Children should be at least 6 months of age (strength of recommendation [SOR]: C, expert opinion) and parents should provide only 100% fruit juice in a cup (not a bottle). Intake should be limited to 4 to 6 oz a day until ...
  • What's the most practical way to rule out adrenal insufficiency? 

    Satre, Thomas J.; Kovach, Fran E. (Family Physicians Inquiries Network, 2009-05)
    A morning serum cortisol level >13 mcg/dL reliably rules out adrenal insufficiency, and the test is easy and safe to perform. Because of low specificity, patients with a level of ≤13 mcg/dL need further evaluation with ...
  • What is the best way to manage phantom limb pain? 

    Black, Lance M.; Persons, Robert K.; Jamieson, Barbara (Family Physicians Inquiries Network, 2009-03)
    No single best therapy for phantom limb pain (PLP) exists. Treatment requires a co- ordinated application of conservative, pharmacologic, and adjuvant therapies. Evaluative management (including prosthesis adjustment, ...
  • What treatment works best for tennis elbow? 

    Beard, J. Mark; Safranek, Sarah (Family Physicians Inquiries Network, 2009-03)
    Topical or oral nonsteroidal anti- inflammatory medications (NSAIDs), corticosteroid injection, and acupuncture are more helpful than placebo in treating lateral epicondylitis, or tennis elbow (strength of recommendation ...
  • What treatments work best for constipation in children? 

    Rahman, Zia; Gerayli, Fereshteh; Carter, Nakia Joyce (Family Physicians Inquiries Network, 2009-06)
    Osmotic laxatives produce the best results. Fiber and behavior modification may have a role. Increased fiber and behavior modification are the most often recommended first steps in managing chronic functional constipation ...
  • What's the best test for renal artery stenosis in patients with refractory hypertension? 

    Stevenson, Michael; Crownover, Brian K.; Mackler, Leslie (Family Physicians Inquiries Network, 2009-04)
    Magnetic resonance angiography (MRA) and computed tomography angiography (CTA) are the most consistently accurate, noninvasive screening methods. MRA is likely the preferred option because of its lack of radiation and ...
  • What is the role of prokinetic agents for constipation? 

    Boyle, Ginger; Mounsey, Anne L.; Crowell, Karen (Family Physicians Inquiries Network, 2009-04)
    Erythromycin has a limited role in treating pediatric patients (strength of recommendation [SOR]: B, limited-quality, patient-oriented evidence). Tegaserod and cisapride are the only prokinetic agents available for ...
  • What are the best prophylactic drugs for migraine? 

    Firnhaber, Jonathon M.; Rickett, Katherine (Family Physicians Inquiries Network, 2009-11)
    Beta-blockers without intrinsic sympathomimetic activity, amitriptyline, divalproex sodium/sodium valproate, and topiramate are the most effective drugs for preventing episodic migraine (strength of recommendation: A, ...
  • What are the most practical primary care screens for post-traumatic stress disorder? 

    Davis, Stephanie M.; Whitworth, James D.; Rickett, Katherine (Family Physicians Inquiries Network, 2009-02)
    The 4-item Primary Care Post-Traumatic Stress Disorder screen (PC-PTSD) is a simple and effective tool to identify symptoms of post-traumatic stress disorder (PTSD) in primary care patients (strength of recommendation [SOR ...

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