Search
Now showing items 21-40 of 841
What are effective therapies for Clostridium difficile- associated diarrhea?
(Family Physicians Inquiries Network, 2005)
select for colonization with vancomycin-resistant enterococci, leading the American College of Gastroenterology to recommend oral metronidazole as preferred therapy (SOR: C, expert opinion). They recommend therapy with vancomycin for those who...
Do TZDs increase the risk of heart failure for patients with diabetes?
(Family Physicians Inquiries Network, 2005)
retrospective cohort study). Still, patients starting any TZD should be warned of the possibility of CHF and should be monitored for its development. TZDs are contraindicated for patients with class III and IV CHF (SOR: C, based on expert opinion)....
Angiotensin blockade for diabetes: Monitor microalbuminuria?
(Family Physicians Inquiries Network, 2007)
No studies address whether continued screening for microalbuminuria once a patient is taking an angiotensin-converting enzyme (ACE) inhibitor or angiotensin-2 receptor blocker (ARB) improves outcomes. Indirect evidence and expert opinion suggest...
What are the causes of hypomagnesemia?
(Family Physicians Inquiries Network, 2005)
, and malnutrition (strength of recommendation: C, based on expert opinion, physiology, and case series). Evidence suggests that magnesium deficiency is both more common and more clinically significant than generally appreciated....
What's the best way to screen for anxiety and panic disorders?
(Family Physicians Inquiries Network, 2007)
The GAD-7 has the best evidence and utility in the primary care setting for generalized anxiety disorder (strength of recommendation [SOR]: A), while the proprietary Quick PsychoDiagnostics Panel (QPD) has the best operating ...
How should we follow up a positive screen for anemia in a 1-year old?
(Family Physicians Inquiries Network, 2005)
complete blood count, mean corpuscular volume, red cell distribution width (RDW), serum ferritin concentration, as well as hemoglobinopathy screening when appropriate, may be effective in determining the cause of anemia (SOR: C, expert opinion)....
Does early detection of suspected atherosclerotic renovascular hypertension change outcomes
(Family Physicians Inquiries Network, 2005)
We found no evidence for changed outcomes from early detection of renal artery stenosis (RAS). Treatment of RAS in refractory hypertension modestly improves blood pressure control. There was a trend toward improved clinical outcomes but studies were...
Statin Therapy in Patients with Type 2 Diabetes
(Family Physicians Inquiries Network, 2005)
Based on current evidence, statin therapy should be offered to all patients with type 2 diabetes who are known to have coronary artery disease. [Strength of recommendation: A] For patients older than 40 years with type 2 diabetes who are not known...
What are the indications for evaluating a patient with cough for pertussis?
(Family Physicians Inquiries Network, 2005)
Pertussis should be considered in infants with apnea or severe coughing illnesses of any duration, and in older children or adults with prolonged cough (eg, longer than 2 weeks), especially if accompanied by inspiratory whoop or household exposure...
What is the best medical therapy for new-onset type 2 diabetes?
(Family Physicians Inquiries Network, 2006)
Sulfonylureas, metformin, thiazolidinediones, and non-sulfonylurea secretagogues differ little in their ability to decrease glycosylated hemoglobin (HbA1c) levels when used as initial monotherapy for diabetes mellitus type 2 (strength...
What are effective treatments for oppositional and defiant behaviors in preadolescents?
(Family Physicians Inquiries Network, 2005)
strategies--including positive attending, ignoring, the effective use of rewards and punishments, token economies, and time out --to address clinically significant behavior problems. In addition to parent training, other psychosocial interventions...
What is the role of combination therapy (insulin plus oral medication) in type 2 diabetes?
(Family Physicians Inquiries Network, 2006)
on systematic review of randomized controlled trials [RCTs] with some heterogeneity). Combination therapy using insulin and pioglitazone (Actos) reduces glycosylated hemoglobin (HbA1c) more than either insulin alone or adding pioglitazone to a sulfonylurea...
What risk factors contribute to C difficile diarrhea?
(Family Physicians Inquiries Network, 2011)
). Hospital risk factors include proximity to other patients with C difficile and longer length of stay (SOR: B, several good-quality cohort studies). Patient risk factors include advanced age and comorbid conditions (SOR: B, several good-quality cohort...
Does quinine reduce leg cramps for young athletes?
(Family Physicians Inquiries Network, 2005)
Very little evidence exists regarding the use of quinine for cramps in young adult athletes. Quinine may be an effective treatment for heat cramps in athletes (strength of recommendation [SOR]: C, 1 case series involving 2 patients). Quinine...
What is the best way to diagnose a suspected rotator cuff tear?
(Family Physicians Inquiries Network, 2006)
The evaluation of a suspected rotator cuff tear should start with a history and a clinical exam of the shoulder (strength of recommendation [SOR]: B, based on a systematic review of cohort studies). Three clinical test results in particular...
What is the best treatment for pertussis?
(Family Physicians Inquiries Network, 2005)
A short-term course of erythromycin, azithromycin, or clarithromycin is as effective as a long-term (2-week) erythromycin therapy in eradicating Bordetella pertussis from the nasopharynx (strength of recommendation [SOR]: A; based on one meta...
Can you differentiate bacterial from viral pediatric infections based on the CBC?
(Family Physicians Inquiries Network, 2007)
No--the complete blood count (CBC) alone does not have adequate sensitivity or specificity to tell bacterial from viral infections (strength of recommendation [SOR]: B, cohort studies). When used in conjunction with other clinical parameters...
What is the best way to manage GERD symptoms in the elderly?
(Family Physicians Inquiries Network, 2006)
than histamine H2 receptor antagonists (H2RAs) (strength of recommendation [SOR]: B, extrapolation from randomized controlled trials [RCTs]). Treating elderly patients with pantoprazole (Protonix) after resolution of acute esophagitis results in fewer...
Preventing Acute Mountain Sickness
(Family Physicians Inquiries Network, 2011)
Gradual ascent is the most effective method for preventing acute mountain sickness. (Strength of Recommendation [SOR]: B, based on good-quality prospective and retrospective cohort studies.) Acetazolamide should be used ...
What's the best way to predict the success of a trial of labor after a previous C-section?
(Family Physicians Inquiries Network, 2015)
Q: What's the best way to predict the success of a trial of labor after a previous C-section? Evidence-based answer: while 8 scoring tools predict success rates for a trial of labor after previous cesarean section (TOLAC), it's unclear which...