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Does moderate exercise prevent MI for patients with coronary heart disease?
(Family Physicians Inquiries Network, 2004)
Moderate exercise reduces mortality for patients with known coronary heart disease but does not significantly decrease the risk of recurrent nonfatal myocardial infarction (MI) (strength of recommendation [SOR]: A, based ...
Does screening for diabetes in at-risk patients improve long-term outcomes?
(Family Physicians Inquiries Network, 2004)
No randomized clinical trials or prospective studies have demonstrated adequate evidence to screen individuals for diabetes mellitus. A recently published meta-analysis for the United States Preventative Services Task Force ...
Does tight control of blood glucose in pregnant women with diabetes improve neonatal outcomes?
(Family Physicians Inquiries Network, 2004)
In pregnant women with preexisting type 1 diabetes mellitus, maintaining near-normal blood glucose levels decreases the rate of major congenital anomalies (defined as those causing death or a serious handicap necessitating ...
Does acyclovir help herpes simplex virus cold sores if treatment is delayed?
(Family Physicians Inquiries Network, 2004)
When herpes simplex virus (HSV) type 1 lesions are in the papule or vesicle stage, there is no benefit to starting oral acyclovir (strength of recommendation [SOR]: C, based on expert opinion). However, topical acyclovir ...
Does yoga speed healing for patients with low back pain?
(Family Physicians Inquiries Network, 2004)
The use of yoga is consistent with recommendations for activity, as tolerated, for patients with low back pain. Literature evaluating the effectiveness of yoga for low back pain is scant, so it is unclear if yoga is ...
Does lowering diastolic BP to less than 90 mm Hg decrease cardiovascular risk?
(Family Physicians Inquiries Network, 2004)
Although lowering diastolic blood pressure (DBP) is associated with reduced cardiovascular events, systolic blood pressure (SBP) is a more robust predictor of cardiovascular risk than DBP and should now be used to diagnose, ...
Does injection of steroids and lidocaine in the shoulder relieve bursitis?
(Family Physicians Inquiries Network, 2004)
Subacromial steroid injection may provide a small, short-term benefit compared with placebo. The short-term effectiveness of steroid injection compared with nonsteroidal anti-inflammatory agents (NSAIDs) remains unclear. ...
Do statins reduce the risk of stroke?
(Family Physicians Inquiries Network, 2004)
HMG Co-A reductase inhibitors (statins) are effective for primary prevention of ischemic stroke in people who have a history of occlusive artery disease, coronary artery disease, or diabetes without history of cerebrovascular ...
How effective is gastric bypass for weight loss?
(Family Physicians Inquiries Network, 2004)
Gastric bypass results in weight loss of approximately 33% at 2 years and 25% at 8 years (strength of recommendation [SOR]: B, based on a cohort study). Gastric bypass is one type of bariatric surgery, which also includes ...
How reliable are self-measured blood pressures taken at home?
(Family Physicians Inquiries Network, 2004)
Self-measured blood pressures (SMBP) can be precise and accurate and, thus, reliably be used as an adjunct to office blood pressure measurements in selected clinical situations (strength of recommendation [SOR]: B, ...
How should thyroid replacement be initiated?
(Family Physicians Inquiries Network, 2004)
Levothyroxine (LT4) should be used alone as initial replacement for patients with hypothyroidism (strength of recommendation [SOR]: A). The optimal initial dose is 1.6 μg/kg/d for healthy people aged 60 years or younger ...
How effective is prophylactic therapy for gout in people with prior attacks?
(Family Physicians Inquiries Network, 2004)
Colchicine (strength of recommendation [SOR]: B, based on 1 double-blind crossover study), allopurinol (SOR: B, based on 2 cohort studies), and weight loss (SOR: B, based on 1 small cohort study) have been shown to reduce ...
How effective are leukotriene inhibitors for asthma in children?
(Family Physicians Inquiries Network, 2004)
Evidence on the use of leukotriene inhibitors in children is insufficient to permit conclusions regarding efficacy. Given the proven efficacy of inhaled corticosteroids in asthma management, leukotriene inhibitors should ...
Does warfarin prevent deep venous thrombosis in high-risk patients?
(Family Physicians Inquiries Network, 2004)
Warfarin (Coumadin) is effective in preventing deep venous thrombosis (DVT) among patients with a history of DVT. Conventional dosing and longer durations are the most effective, but the ideal length of therapy is unknown ...
Does treatment of acne with Retin A and tetracycline cause adverse effects?
(Family Physicians Inquiries Network, 2004)
Self-Adverse reactions to long-term tetracycline therapy are rare, and most will occur within 2 months of initiating therapy (strength of recommendation [SOR]: B, systematic review of ecological studies). Rare but serious ...
Does a short symptom checklist accurately diagnose ADHD?
(Family Physicians Inquiries Network, 2004)
Several abbreviated checklists perform well in distinguishing children with attention deficit/ hyperactivity disorder (ADHD) from those without ADHD under ideal conditions and in research settings. While many guidelines ...
Does combining aspirin and warfarin decrease the risk of stroke for patients with nonvalvular atrial fibrillation?
(Family Physicians Inquiries Network, 2004)
Adjusted-dose warfarin (international normalized ratio [INR]=2.0-3.0) remains the most efficacious antithrombotic regimen for the primary and secondary prevention of cardioembolic stroke in high-risk patients with nonvalvular ...
Do routine eye exams reduce occurrence of blindness from type 2 diabetes?
(Family Physicians Inquiries Network, 2004)
Screening eye exams for patients with type 2 diabetes can detect retinopathy early enough so treatment can prevent vision loss. Patients without diabetic retinopathy who are systematically screened by mydriatic retinal ...
Do steroid injections help with osteoarthritis of the knee?
(Family Physicians Inquiries Network, 2004)
Intra-articular steroid injections appear to provide 2 to 6 weeks of pain relief for patients with knee osteoarthritis (strength of recommendation [SOR]: A). Higher-dose steroids with or without joint lavage can provide ...
For knee pain, how predictive is physical examination for meniscal injury?
(Family Physicians Inquiries Network, 2004)
No single clinical examination element, or combination of such elements, reliably detects meniscal injury. The McMurray test is best for ruling in meniscal pathology. Assuming a 9% prevalence of meniscal tears among all ...